User:SukYeon Hwang

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Nathan SukYeon Hwang

PhD Candidate (Dr. Jennifer Elisseeff lab)
Department of Biomedical Engineering
Johns Hopkins School of Medicine
E-Mail : hwang@jhu.edu
Nathan's website

Research

Cartilage/bone tissue engineering
Microenvironment-mediated embryonic stem cell self-renewal and differentiation
Biomaterials-directed commitment and tissue formation of stem cells

Education and Professional Training

• Fall 2002- Present:
  Johns Hopkins University School of Medicine, Baltimore, MD
  PhD candidate, Department of Biomedical Engineering
  Advisor: Jennifer Elisseeff, PhD
• Fall 1998-May 2002:
  Johns Hopkins University School of Engineering, Baltimore, MD (Class of 2002)
  Biomedical Engineering (BME) with minor in Computer Science

Honors and Awards

• Student Award (January, 2006)
  Award based on merit of paper presentation and content: The Society for Physical Regulation in Biology and Medicine (Jan, 2006)
  
• Student Travel Award (January, 2006)
  Travel award presented by the Society for Physical Regulation in Biology and Medicine 24th Scientific Conference.
  
• Graduate Student Travel Award (June 2005)
  Travel award presented by Graduate Student Association
  
• Tau Beta Pi – Inducted as Junior class (2001)
  Honor society invitation given to the top 8% of the engineering junior class based on academic merit.
  
• Golden Key National Honor Society (2000)
  Honor society invitation given to the top 15% of the class (120 out of 937) based on academic merit and involvement in community service.
• Biomedical Engineering Honor Society (2001)
  Honor society invitation given to top 20% BME majors based on academic merit.
  
• Korean Scholar (2000)
  Selected by Korean Embassy in Washington, D.C. based on academic merit.
  
• Summer Undergraduate Research Fellowship at Southwestern Medical Center at Dallas (Summer 2000)
  
• PCUSA (Presbyterian Church of U.S.A) Scholarship (2000)
  
• Honorable Mention in Proposal to the 2002 Undergraduate Materials Research Initiative
  
• Honorable Mention in Proposal to the 2000 Undergraduate Materials Research Initiative

Publications

1. Hwang, NS., Varghese, S., Zhang, Z., and Elisseeff, J. “Tissue Engineering Using Embryonic Stem Cells: Modulation of chondrogenesis by the extracellular microenvironment" (Advanced Drug Delivery Review, in preparation)
   
2. Hwang, NS., Varghese, S., Zhang, Z., and Elisseeff, J. “Cartilage Tissue Engineering using Human ES-Derived Chondrocytes” (In Preparation)
   
3. Hwang, NS., Varghese, S., Li, H., and Elisseeff, J. “Extracellular Microenvironment Regulation of Osteogenic and Chondrogenic Differentiation of Mesenchymal Stem Cells” Journal of Biomedical Materials Research (submitted)
   
4. Varghese, S., Ferran, A., Hwang, NS.,Hilllel, A., Theprungsirkul, P., Zhang, Z., Shamblott, M., Gearhart, J., and Elisseeff, J. “Characterization and functional mesenchymal differentiation of human embryonic stem cells” Nature Biotechnology (In Revision)
   
5. Hwang, NS., Shyni Varghese, Lee, J., Zhang, Z., and Elisseeff, J. “Biomaterials-Directed In Vivo Commitment of Mesenchymal Cells Derived From Human Embryonic Stem Cells” FASEB Journal (Under Review)
   
6. Shyni Varghese, Canver, CA., Hwang, NS., Lin, D., Theprungsirikul, P., Elisseeff, J. ”Chondroitin sulfate based hydrogel niche for chondrogenic differentiation of mesenchmymal stem cells”, Matrix Biology (In press)
   
7. Lee, H.J., Yu, C., Chansakul, T., Hwang, N.S., Varghese, S., and Elisseeff, J. “Enhanced chondrogenesis of mesenchymal stem cells in collagen mimetic peptide-modified microenvironment”, Matrix Biology (Under Review)
   
8. Hwang, NS., Varghese, S., Sampattavanich, S., Sharma, B., Canver, A., and Elisseeff, J.“Reponse of Zonal Chondrocytes in Extracellular Matrix-Hydrogels” FEBS Letters (In Revision)
   
9. Hwang, NS., Varghese, S., Puleo C., Zhang, Z., and Elisseeff, J. “Morphogenetic Signals from Chondrocytes Promote Chondrogenic and Osteogenic Differentiation of Mesenchymal Stem Cells” Journal of Cellular Physiology (In Press)
   
10. Varghese, S., Paranduangji, T., Sabani, S., Hwang, NS., Yarema, K., Elisseeff, J.“Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression”Osteoarthritis and Cartilage (In Press)
    
11. Zhang, Z., Messana, J., Hwang, NS., Elisseeff J. “Reorganization of Actin Filaments Enhances Chondrogenic Differentiation of Cells Derived from Murine Embryonic Stem Cells” Biochemical and Biophysical Research Communication 2006 Sep 22;348(2):421-7
    
12. Varghese S, Theprungsirikul P, Ferran A, Hwang NS, Elisseeff J H “Chondrogenic differentiation of human embryonic germ cell derived cells in hydrogels” EMB IEEE (In Press)
13. Elisseeff J H, Ferran A, Hwang NS, Varghese S, Zhang Z. “The role of biomaterials in stem cell differentiation: Application in the musculoskeletal system” Stem Cells and Development 2006; 15(3): 295-303.
    
14. Hwang, NS*., Varghese* S., Theprungsirikul, T., Canver, A., and Elisseeff, J. “Enhanced Chondrogenic Differentiation of Murine Embryonic Stem Cells in Hydrogels by Glucosamine Treatment” Biomaterials 2006; 27(36): 6015-23 (* Contributed equally to this work)
    
15. Hwang, NS., Varghese, S., Zhang, Z., and Elisseeff, J. “Chondrogenic Differentiation of Human Embryonic Stem Cell-derived Cells in RGD-Modified Hydrogels” Tissue Engineering 2006; 12(9):2695-2706.
    
16. Hwang, NS., Kim, M., Sampattavanich, S., Baek, J.H.,Zhang, Z., Elisseeff, J. “Effects of Three Dimensional Culture and Growth Factors on the Chondrogenic Differentiation of Murine Embryonic Stem Cells” Stem Cells 2006; 24(2):284-291.
    
17. Kim, M.S., Hwang, NS., Lee, J., Kim, T.K., Shamblott, M., Gearhart, J., Elisseeff, J. (2005).“Musculoskeletal differentiation of Cells Derived from Human Embryonic Germ Cells”. Stem Cells 2005; 23(1):113-23.
    

Book Chapters

• Hwang, N., Varghese, S., and Elisseeff, J. “Cartilage Tissue Engineering: Directing Differentiation of Embryonic Stem Cells in Three-Dimensional Culture”, Humana Press: Methods in Molecular Biology-Stem Cell Assays (In Press)
  
• Lee, J., Varghese, S., Hwang, N., and Elisseeff, J. “Hydrogels for Cartilage Tissue Engineering: Modulation of Chondrogenesis by Extracellular Microenvironment”, Artech House Publishing Inc. Micro- and Nanoengineering of the Cell Microenvironment: Technologies and Applications (Submitted)