User:Sunny Sharma: Difference between revisions
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== Awards == | == Awards == | ||
EMBO (European Molecular Biology Organisation) Long Term Fellowship. (2014-2016)[http://www.embo.org/] | |||
DAAD (Deutsche Akademische Austauschdienst) PhD scholarship (2010 - 2013) [https://www.daad.de/de/index.html] | DAAD (Deutsche Akademische Austauschdienst) PhD scholarship (2010 - 2013) [https://www.daad.de/de/index.html] | ||
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# Ribosome Biogenesis | # Ribosome Biogenesis | ||
# RNA modifications | # RNA modifications | ||
# Developmental Biology | |||
#Immunology | #Immunology | ||
# Gerontology | # Gerontology | ||
==Publications== | ==Publications== | ||
1) | |||
1) Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans. [http://nar.oxfordjournals.org/content/early/2016/04/15/nar.gkw244.abstract] | |||
2)‘View From A Bridge’: A New Perspective on Eukaryotic rRNA Base Modification.[http://www.cell.com/trends/biochemical-sciences/abstract/S0968-0004%2815%2900139-5] | |||
3) The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent.[http://nar.oxfordjournals.org/content/early/2015/09/13/nar.gkv895.full] | |||
4) Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1.[http://nar.oxfordjournals.org/content/early/2015/02/03/nar.gkv075.full] | |||
5) Identification of a new ribose methylation in the 18S rRNA of S. cerevisiae.[http://nar.oxfordjournals.org/content/early/2015/02/03/nar.gkv058.abstract] | |||
6) Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.[http://www.ncbi.nlm.nih.gov/pubmed/25635753] | |||
7) Absolute and relative quantification of RNA modifications via biosynthetic isotopomers.[http://www.ncbi.nlm.nih.gov/pubmed/25129236] | |||
8) Partial methylation at Am100 in 18S rRNA of baker´s yeast shows ribosome heterogeneity on the level of eukaryotic rRNA modification. Plos One [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0089640] | |||
9) Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.[http://nar.oxfordjournals.org/content/early/2013/12/11/nar.gkt1281.full] | |||
10) Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively.[http://www.ncbi.nlm.nih.gov/pubmed/23913415] | |||
11) Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae.[http://www.ncbi.nlm.nih.gov/pubmed/23558746] | |||
12) Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.[http://www.ncbi.nlm.nih.gov/pubmed/23180764] | |||
13) Association of P2X7 receptor +1513 (A-->C) polymorphism with tuberculosis in a Punjabi population.[http://www.ncbi.nlm.nih.gov/pubmed/20819262] | |||
==Conferences/ Workshops== | ==Conferences/ Workshops== | ||
# Plenary talk at 10th Ribosome Synthesis meeting 19th-25th August, Brussels.[http://events.embo.org/15-ribosomes/] | |||
# Seminar at RNA club, 16th October 2013 [http://www.rnaclub.de/img/RNACLUB_20131016.pdf ] | # Seminar at RNA club, 16th October 2013 [http://www.rnaclub.de/img/RNACLUB_20131016.pdf ] | ||
# Plenary talk at Yeast Meeting, Frankfurt 2013 [http://www.yeast-2013.org/faces/index] | # Plenary talk at Yeast Meeting, Frankfurt 2013 [http://www.yeast-2013.org/faces/index] | ||
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==Useful links== | ==Useful links== | ||
*http://www.muk.uni-frankfurt.de/53895688/033? | |||
*http://www.yeastgenome.org/ | *http://www.yeastgenome.org/ | ||
*http://www.rnaclub.de | *http://www.rnaclub.de |
Revision as of 00:23, 17 April 2016
Contact Info
- Sunny Sharma
- Institute of Molecular Biosciences, Max-von-Laue Strasse-9, Campus Riedberg, Goethe University
- Frankfurt am Main, Hesse, Germany.
- Email me through OpenWetWare
Research Associate at Goethe University, Frankfurt am Main.
Education
- Research Associate at Institute of Molecular Biosciences, Goethe University, Frankfurt am Main, Germany [1]
- 2014, PhD (Biology), Goethe University, Frankfurt am Main, Germany [2]
- 2007, MS (Molecular Biology & Biochemistry), Guru Nanak Dev University, Amritsar, India [3]
- 2005, BS, Bangalore University, Bangalore, India [4]
Awards
EMBO (European Molecular Biology Organisation) Long Term Fellowship. (2014-2016)[5]
DAAD (Deutsche Akademische Austauschdienst) PhD scholarship (2010 - 2013) [6]
CEF (Excellence Cluster-Frankfurt am Main) PhD fellowship (2009 - 2010) [7]
ICMR (Indian Council of Medical Research) Junior Research Fellowship (2009 - 2010) [8]
Research interests
- Ribosome Biogenesis
- RNA modifications
- Developmental Biology
- Immunology
- Gerontology
Publications
1) Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans. [9]
2)‘View From A Bridge’: A New Perspective on Eukaryotic rRNA Base Modification.[10]
3) The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent.[11]
4) Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1.[12]
5) Identification of a new ribose methylation in the 18S rRNA of S. cerevisiae.[13]
6) Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.[14]
7) Absolute and relative quantification of RNA modifications via biosynthetic isotopomers.[15]
8) Partial methylation at Am100 in 18S rRNA of baker´s yeast shows ribosome heterogeneity on the level of eukaryotic rRNA modification. Plos One [16]
9) Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.[17]
10) Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively.[18]
11) Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae.[19]
12) Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA.[20]
13) Association of P2X7 receptor +1513 (A-->C) polymorphism with tuberculosis in a Punjabi population.[21]
Conferences/ Workshops
- Plenary talk at 10th Ribosome Synthesis meeting 19th-25th August, Brussels.[22]
- Seminar at RNA club, 16th October 2013 [23]
- Plenary talk at Yeast Meeting, Frankfurt 2013 [24]
- Poster presentation at 18th Annual RNA meeting of the RNA society, Davos, Switzerland [25]
- Seminar at RNA club, 26th September 2012 [26]
- Poster presentation at 9th International Conference on Ribosome Synthesis, Banff, Canada [27]
Useful links
- http://www.muk.uni-frankfurt.de/53895688/033?
- http://www.yeastgenome.org/
- http://www.rnaclub.de
- http://people.biochem.umass.edu/fournierlab/3dmodmap/main.php
- http://modomics.genesilico.pl/
- http://www.rna.icmb.utexas.edu/
- http://espript.ibcp.fr/ESPript/cgi-bin/ESPript.cgi
- http://www.sbg.bio.ic.ac.uk/phyre2/html/page.cgi?id=index