User:TheLarry/Notebook/Larrys Notebook/2009/08/02
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KMC of KPI think my states from yesterday might be a bit too simple. After talking to Koch, he reminded me there has to be a step where the ADP Foot combo unbinds from the MT. As well as the ability to step forward or remind at the same spot. Also there maybe some kind of wait state or something.
Also there is a cooperation between each foot.
NextOk I made the above diagram. Now shoul i try to implement into a stepping mechanism. I don't think it'll be too tough. I have to add in the constraints. So basically i gotta make it impossible for certain steps before the other head has done some stuff. But then do I want to make it that complicated or should I use a simpler model and not worry about closed/open/trapped states. I don't want to do this any more today. Tomorrow i'll talk to Koch about it and see what he says. For the record here is my simpler model. of course i don't have the drawing skills ant has. I can make a quick program in like half an hour so if i get the chemistry/biology down i can have this done before the end of the week. I don't like working on the weekend without a sweet looking program to show for the work. QuestionsI still don't know how the whole ATPase will detach from the MT. There seems to be an ATP or ADP induced detachment but i don't know what states this occurs in. I'll ask Koch about it tomorrow. |