User:Thomas Dziubla

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[[Image:dziubla1.jpg|150px|left|]]
[[Image:dziubla1.jpg|150px|left|]]
==Thomas Dziubla==
==Thomas Dziubla==
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Assistant Professor, Department of Chemical and Materials Engineering, University of Kentucky<p>
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'''Assistant Professor'''<br>Department of Chemical and Materials Engineering <br>University of Kentucky<br>
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Postdoctoral Fellow, Institute for Environmental Medicine, University of Pennsylvania<br>
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==Education==
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PhD. Chemical Engineering,  Drexel University<br>
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'''Postdoctoral Fellow''', Institute for Environmental Medicine, University of Pennsylvania, Philadelphia PA<br>
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Honors B.S. Chemical Engineering, Purdue University<br>
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'''PhD. Chemical Engineering''',  Drexel University, Philadelphia, PA<br>
 +
'''Honors B.S. Chemical Engineering'''', Purdue University, West Lafayette, IN<br><BR><br>
 +
 
 +
==Awards and Honors==
 +
NIH NRSA Postdoctoral Fellow, Institute of Environmental Medicine<br>
 +
3rd Place Research Award: Molecular Design In Drug Discovery & Development Symposium Series(2004)<br>
 +
Biomaterials Annual Conference Travel Award:Honorable Mention(2003)<br>
 +
Drexel University Graduate Student Research Award(2001)<br>
 +
Mollye and Mitchell Glick Scholarship Award(2001)<br>
 +
American Institute of Chemists Award, Drexel University(2000)<br>
 +
Sigma Xi Research Day-Graduate Student Research Award(2000)<br>
 +
Drexel University Dean’s Fellowship Award(1998,1999)<br>
 +
 
 +
==Publications==
 +
C. Garnacho, R. Dhami, E. Simone, T. Dziubla, J. Leferovich, E. H. Schuchman, V. Muzykantov, and S. Muro*. “Delivery of acid sphingomyelinase in normal and Niemann-Pick disease mice using ICAM-1-targeted polymer nanoparticles” JPET (In Revision)
 +
 
 +
E. Simone, T. Dziubla, V Shuvaev and V.R. Muzykantov, “Synthesis and Characterization of Polymer Nanocarriers for Therapeutic Enzyme Delivery.” In:, 2nd Edition for Methods in Molecular Biology: Free Radicals and Antioxidant Protocols (In Press)
 +
 
 +
D. Besser, G. Swan, T. Dziubla and R. Eitel, “Building Continuous Loop Learning Communities: An Engineering Outreach Case Study” ASEE Southeast Spring Conference Proceedings (2008)
 +
 
 +
T.D. Dziubla*, V.V. Shuvaev, N.K. Hong, B. Hawkins, M. Muniswamy, H. Takano, E. Simone, M.T. Nakada, A. Fisher, S.M. Albelda, and V.R. Muzykantov, “Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies.” Biomaterials 2:215-27 (2008)
 +
 
 +
E. Simone*, T. Dziubla, F. Colon, D. Discher and V.R. Muzykantov. “Amphiphilicity of PEG-PLA diblock copolymer controls the formulation and morphology of nanocarriers protecting loaded therapeutic enzyme from proteolysis” Biomacromolecules 8:3914-21 (2007)
 +
 
 +
S. Muro*, T.D. Dziubla, W. Qui, J. Leferovich, X. Cui, E. Berk and V.R. Muzykantov  “Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to ICAM-1.” JPET 317(3):1161-9 (2006)
 +
 
 +
Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR. “Advanced drug delivery systems that target the vascular endothelium.” Mol Interv. 2:98-112 (2006)
 +
 +
T.D. Dziubla and V. Muzykantov, “Nanocarriers for drug delivery to the pulmonary vasculature.” In: Nanoparticulates as Drug Carriers, V Torchilin, Ed. Imperial College Press, London. (2006)
 +
 
 +
T.D. Dziubla and V. Muzykantov, “Synthetic carriers for the delivery of protein therapeutics.” In: Biotechnology and Genetic Engineering Reviews Vol. 22., S.E. Harding Ed., Lavoisier Publishing, Paris, France 267-298 (2006)
 +
 
 +
T. Dziubla, S. Muro, V. R. Muzykantov and M. Koval, “Nanoscale antioxidant therapeutics.” In: Oxidative Stress, Disease and Cancer, Keshav K. Singh, Ed. Imperial College Press, London. (2006)
 +
 
 +
T.D. Dziubla*, A. Karim and V. Muzykantov, “Polymer nanocarriers (PNC) protect loaded catalase cargo from proteolysis.” Journal of Controlled Release 102(2), 427-439, (2005)
 +
 
 +
T.D. Dziubla and A.M. Lowman*, “Vascularization of PEG-grafted macroporous hydrogel sponges: a 3-dimensional in vitro angiogenesis model utilizing human microvascular endothelial cells.” Journal of Biomedical Materials Research. 68A (4): 603-614, (2004)
 +
 
 +
A.M. Lowman, T.D. Dziubla, P. Bures and N.A. Peppas, “Structural and dynamic response of neutral and intelligent networks in biomedical environments.” in N.A. Peppas and M.V. Sefton, eds., “Advances in Chemical Engineering Vol 29: Molecular and Cellular Foundations of Biomaterials.” Academic Press, New York, (2004)
 +
 
 +
V. Shuvaev, T. Dziubla, R. Wiewrodt and V. Muzykantov, “Streptavidin-biotin cross-linking of therapeutic enzymes with carrier antibodies: nanoconjugates for protection against endothelial oxidative stress.” In: Methods in Molecular Biology V 283: Bioconjugation Protocols: Strategies and Methods, C.Niemeyer, Ed., Humana Press, (2004)
 +
 
 +
T.D. Dziubla, M.C. Torjman, J.I. Joseph and A.M. Lowman, “Implantable drug delivery devices: design of a biomimetic interfacial drug delivery system.” In: Biomimetic Materials and Design: Interactive Biointerfacial Strategies, Tissue Engineering, and Targeted Drug Delivery, A K Dillow and A M Lowman, Eds., Marcel Dekker, (2003)
 +
 
 +
T.D. Dziubla and A.M. Lowman, “Smart gels.” In: Encyclopedia of Smart Materials, M. Schwartz  Ed. Wiley and Sons, (2001)
 +
 
 +
T.D. Dziubla, M.C. Torjman, J.I. Joseph, M. Murphy-Tatum and A.M. Lowman*, "Evaluation of porous networks of poly(2-hydroxyethyl methacrylate) as interfacial drug delivery devices." Biomaterials 22, 2893-2899, (2001)
 +
 
 +
A.M. Lowman, T.D. Dziubla and N.A. Peppas, “Novel networks and gels containing increased amounts of grafted and crosslinked poly(ethylene glycol).” ACS Polymer Prepr., 38(1), (1997)
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</div>
 
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[[dziubla Lab|Home]]
[[dziubla Lab|Home]]

Revision as of 00:13, 5 March 2008

Resources

Protocols
Equipment

  • DLS
  • Glovebox
  • Fluorimeter
  • Freeze Dryer
  • Uv-Vis
  • GPC/HPLC

Materials
Internal

Contact

Thomas Dziubla
Assistant Professor
Mat and Chem Engineering
University of Kentucky
177 F Paul Anderson Tower
Lexington, KY 40506-0046
dziubla-at-engr.uky.edu

Thomas Dziubla

Assistant Professor
Department of Chemical and Materials Engineering
University of Kentucky

Education

Postdoctoral Fellow, Institute for Environmental Medicine, University of Pennsylvania, Philadelphia PA
PhD. Chemical Engineering, Drexel University, Philadelphia, PA
Honors B.S. Chemical Engineering', Purdue University, West Lafayette, IN


Awards and Honors

NIH NRSA Postdoctoral Fellow, Institute of Environmental Medicine
3rd Place Research Award: Molecular Design In Drug Discovery & Development Symposium Series(2004)
Biomaterials Annual Conference Travel Award:Honorable Mention(2003)
Drexel University Graduate Student Research Award(2001)
Mollye and Mitchell Glick Scholarship Award(2001)
American Institute of Chemists Award, Drexel University(2000)
Sigma Xi Research Day-Graduate Student Research Award(2000)
Drexel University Dean’s Fellowship Award(1998,1999)

Publications

C. Garnacho, R. Dhami, E. Simone, T. Dziubla, J. Leferovich, E. H. Schuchman, V. Muzykantov, and S. Muro*. “Delivery of acid sphingomyelinase in normal and Niemann-Pick disease mice using ICAM-1-targeted polymer nanoparticles” JPET (In Revision)

E. Simone, T. Dziubla, V Shuvaev and V.R. Muzykantov, “Synthesis and Characterization of Polymer Nanocarriers for Therapeutic Enzyme Delivery.” In:, 2nd Edition for Methods in Molecular Biology: Free Radicals and Antioxidant Protocols (In Press)

D. Besser, G. Swan, T. Dziubla and R. Eitel, “Building Continuous Loop Learning Communities: An Engineering Outreach Case Study” ASEE Southeast Spring Conference Proceedings (2008)

T.D. Dziubla*, V.V. Shuvaev, N.K. Hong, B. Hawkins, M. Muniswamy, H. Takano, E. Simone, M.T. Nakada, A. Fisher, S.M. Albelda, and V.R. Muzykantov, “Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies.” Biomaterials 2:215-27 (2008)

E. Simone*, T. Dziubla, F. Colon, D. Discher and V.R. Muzykantov. “Amphiphilicity of PEG-PLA diblock copolymer controls the formulation and morphology of nanocarriers protecting loaded therapeutic enzyme from proteolysis” Biomacromolecules 8:3914-21 (2007)

S. Muro*, T.D. Dziubla, W. Qui, J. Leferovich, X. Cui, E. Berk and V.R. Muzykantov “Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to ICAM-1.” JPET 317(3):1161-9 (2006)

Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR. “Advanced drug delivery systems that target the vascular endothelium.” Mol Interv. 2:98-112 (2006)

T.D. Dziubla and V. Muzykantov, “Nanocarriers for drug delivery to the pulmonary vasculature.” In: Nanoparticulates as Drug Carriers, V Torchilin, Ed. Imperial College Press, London. (2006)

T.D. Dziubla and V. Muzykantov, “Synthetic carriers for the delivery of protein therapeutics.” In: Biotechnology and Genetic Engineering Reviews Vol. 22., S.E. Harding Ed., Lavoisier Publishing, Paris, France 267-298 (2006)

T. Dziubla, S. Muro, V. R. Muzykantov and M. Koval, “Nanoscale antioxidant therapeutics.” In: Oxidative Stress, Disease and Cancer, Keshav K. Singh, Ed. Imperial College Press, London. (2006)

T.D. Dziubla*, A. Karim and V. Muzykantov, “Polymer nanocarriers (PNC) protect loaded catalase cargo from proteolysis.” Journal of Controlled Release 102(2), 427-439, (2005)

T.D. Dziubla and A.M. Lowman*, “Vascularization of PEG-grafted macroporous hydrogel sponges: a 3-dimensional in vitro angiogenesis model utilizing human microvascular endothelial cells.” Journal of Biomedical Materials Research. 68A (4): 603-614, (2004)

A.M. Lowman, T.D. Dziubla, P. Bures and N.A. Peppas, “Structural and dynamic response of neutral and intelligent networks in biomedical environments.” in N.A. Peppas and M.V. Sefton, eds., “Advances in Chemical Engineering Vol 29: Molecular and Cellular Foundations of Biomaterials.” Academic Press, New York, (2004)

V. Shuvaev, T. Dziubla, R. Wiewrodt and V. Muzykantov, “Streptavidin-biotin cross-linking of therapeutic enzymes with carrier antibodies: nanoconjugates for protection against endothelial oxidative stress.” In: Methods in Molecular Biology V 283: Bioconjugation Protocols: Strategies and Methods, C.Niemeyer, Ed., Humana Press, (2004)

T.D. Dziubla, M.C. Torjman, J.I. Joseph and A.M. Lowman, “Implantable drug delivery devices: design of a biomimetic interfacial drug delivery system.” In: Biomimetic Materials and Design: Interactive Biointerfacial Strategies, Tissue Engineering, and Targeted Drug Delivery, A K Dillow and A M Lowman, Eds., Marcel Dekker, (2003)

T.D. Dziubla and A.M. Lowman, “Smart gels.” In: Encyclopedia of Smart Materials, M. Schwartz Ed. Wiley and Sons, (2001)

T.D. Dziubla, M.C. Torjman, J.I. Joseph, M. Murphy-Tatum and A.M. Lowman*, "Evaluation of porous networks of poly(2-hydroxyethyl methacrylate) as interfacial drug delivery devices." Biomaterials 22, 2893-2899, (2001)

A.M. Lowman, T.D. Dziubla and N.A. Peppas, “Novel networks and gels containing increased amounts of grafted and crosslinked poly(ethylene glycol).” ACS Polymer Prepr., 38(1), (1997)

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