User:Thomas Dziubla

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== Thomas Dziubla ==
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[[Image:dziubla1.jpg|150px|left|]]
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==Thomas Dziubla==
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'''Assistant Professor'''<br>Department of Chemical and Materials Engineering <br>University of Kentucky<br>
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[[Image:OWWEmblem.png|thumb|left|Thomas Dziubla (an artistic interpretation)]]
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==Education==
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'''Postdoctoral Fellow''', Institute for Environmental Medicine, University of Pennsylvania, Philadelphia PA<br>
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'''PhD. Chemical Engineering''',  Drexel University, Philadelphia, PA<br>
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'''Honors B.S. Chemical Engineering'''', Purdue University, West Lafayette, IN<br><BR><br>
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Hi, my name is Thomas Dziubla, and I'm currently at University of Kentucky. I learned about [[OpenWetWare]] from Pam Kreeger recommended the system, and I've joined because I would like to have an easy access/easy to update website for publicizing my reasearch group.  You can [[Special:Emailuser/Thomas Dziubla|email me through OpenWetWare]].
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==Awards and Honors==
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NIH NRSA Postdoctoral Fellow, Institute of Environmental Medicine<br>
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3rd Place Research Award: Molecular Design In Drug Discovery & Development Symposium Series(2004)<br>
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Biomaterials Annual Conference Travel Award:Honorable Mention(2003)<br>
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Drexel University Graduate Student Research Award(2001)<br>
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Mollye and Mitchell Glick Scholarship Award(2001)<br>
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American Institute of Chemists Award, Drexel University(2000)<br>
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Sigma Xi Research Day-Graduate Student Research Award(2000)<br>
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Drexel University Dean’s Fellowship Award(1998,1999)<br>
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== Welcome Thomas Dziubla! ==
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==Publications==
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M. Howard, X. Lu, J. Rinehart, M. Jay and T. Dziubla* “Physicochemical Characterization of Nanotemplate Engineered Solid Lipid Nanoparticles” Langmuir (Accepted)
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We've automatically generated this User page to help you start contributing to OWW. You can add information to this page about who you are and what you do so others can find out what you are doing, and maybe even collaborate with you!
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J. Kim, M. Howard, T. Dziubla, J. Rinehart, M. Jay and X. Lu * “Uniformity of Drug Payload and its Effect on Stability of Solid Lipid Nanoparticles Containing an Ester Prodrug” ACS Nano (accepted)
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The first step is to familiarize yourself with a wiki. See below for some tips to customize this User page.  Don't be afraid to edit!  As with all pages on the wiki, all versions are saved so its easy to undo.
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J. Medley, Heisterberg J, and T Dziubla* “Synthesis and Characterization of CREKA-Targeted Polymers for the Disruption of Fibrin Gel Matrix Propagation.” J Biomater Sci:Poly Ed (E Pub 2010)
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When you feel comfortable, we encourage you to remove this introduction and add content about yourself.
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P. Wattamwar, Y. Mo, R. Wan, R. Palli, Q. Zhang and T. Dziubla*, “Antioxidant Activity of Degradable Polymer Poly(trolox ester) to Suppress Oxidative Stress Injury in the Cells.” Advanced Functional Materials 20:147-154 (2010)
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== Basic Wiki Instructions ==
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Y Ma, Y Xiong*, J Zhai, H Zhu, and T Dziubla, “Fractionation and Evaluation of Radical Scavenging Peptides from in vitro Digests of Buckwheat Protein.” Food Chemistry 118:582-588 (2010)
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# Start off by clicking the 'edit' button to the right of this section, or at the top of the page.
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J. Medley, E. Beane, E. Kaplan and T Dziubla* “Block copolymers for the rational design of self-forming postsurgical adhesion barriers.” Acta Biomaterialia 6:72-82 (2010)
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# Now you should see the text of this section as text within an editor box.  There are several buttons in the editor box, but don't worry about those for now. Just type something in the box, scroll down to the bottom, and hit the 'Preview' button.
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# You should see the web-page and text box views, but now with your edits!  Don't forget to save your changes by clicking 'Save Page'!
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# Editing pages is as easy as that.  There are of course many ways to format your text.  The easiest way to learn is to find an OWW page with the formatting you like, click on the edit button again, and see for yourself how it was created in the text box.  Here's an extensive list of [http://en.wikipedia.org/wiki/Wikipedia:Tutorial_%28Formatting%29 formating examples]. Or look at this OpenWetWare [[OpenWetWare:Welcome|introductory tutorial]]. 
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# When you are done, remove these instructions by clicking the edit button for this section again, erase everything you see in the text box and click 'Save Page'. (And remember you can always retrieve these by clicking on the 'history' tab at the top of this page.)
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Note that these instructions apply to ''any'' page on OWW.  Feel free to contribute to OWW by editing pages to add content, update them, or even correct mistakes.  OWW relies on an active community to manage our growing resource of open access information, and we need your help!
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E Simone*, T Dziubla, D Discher, and V Muzykantov. “Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase.” Biomacromolecules 10:1324-30 (2009)
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== Personal/Lab Info ==
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E Simone*, T. Dziubla, E Arguiri, V Vardon, V Shuvaev, M Christofidou-Solomidou and V Muzykantov. “Loading PEG-catalase into filamentous and spherical polymer nanocarriers” Pharmaceutical Research 26:250-60 (2009)
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We have gone ahead and filled in some information you provided us in your membership application at the top of this page.  Please take a moment to embellish this and tell the community a little more about you.  Put links to your lab pages, your projects and your interests. If you run out of ideas, take a look at some of the other User pages.  For example, check out [[User:Julius_B._Lucks]], [[User:Jason_R._Kelly]] and [[User:Reshma_P._Shetty]]. 
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You'll also notice that we have put an 'image' placeholder at the top of the page. We encourage you to upload an image of yourself to give OWW a more personal feel.  To upload an image, click on the [[Special:Upload|Upload file]] link on the left-hand side (toolbar). Choose a file from your computer, and remember the file name. After you have uploaded the image, you should see it loaded on its own page. User your browser's back button to come back to this page, click on edit, and replace 'OWWEmblem.png' with the name of your file that you have uploaded in the second line of this page.
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E. Simone, T.D. Dziubla, and V. R Muzykantov., “Polymeric Carriers: Role of Geometry in Drug Delivery.” Expert Opinion on Drug Delivery 5:1283-1300 (2008)
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Don't forget to remove these instructions from this page when you are done!
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M. Howard, M Jay, T. Dziubla, X. Lu*, “PEGylation of Nanocarrier Drug Delivery Systems: State of the Art.” J Biomed Nanotech 4:133-148 (2008)
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C. Garnacho, R. Dhami, E. Simone, T. Dziubla, J. Leferovich, E. H. Schuchman, V. Muzykantov, and S. Muro*. “Delivery of acid sphingomyelinase in normal and Niemann-Pick disease mice using ICAM-1-targeted polymer nanoparticles” JPET 325:400-408 (2008)
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T.D. Dziubla*, V.V. Shuvaev, N.K. Hong, B. Hawkins, M. Muniswamy, H. Takano, E. Simone, M.T. Nakada, A. Fisher, S.M. Albelda, and V.R. Muzykantov, “Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies.” Biomaterials 2:215-27 (2008)
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E. Simone*, T. Dziubla, F. Colon, D. Discher and V.R. Muzykantov. “Amphiphilicity of PEG-PLA diblock copolymer controls the formulation and morphology of nanocarriers protecting loaded therapeutic enzyme from proteolysis” Biomacromolecules 8:3914-21 (2007)
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S. Muro*, T.D. Dziubla, W. Qui, J. Leferovich, X. Cui, E. Berk and V.R. Muzykantov  “Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to ICAM-1.” JPET 317(3):1161-9 (2006)
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Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR. “Advanced drug delivery systems that target the vascular endothelium.” Mol Interv. 2:98-112 (2006)
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T.D. Dziubla*, A. Karim and V. Muzykantov, “Polymer nanocarriers (PNC) protect loaded catalase cargo from proteolysis.” Journal of Controlled Release 102(2), 427-439, (2005)
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T.D. Dziubla and A.M. Lowman*, “Vascularization of PEG-grafted macroporous hydrogel sponges: a 3-dimensional in vitro angiogenesis model utilizing human microvascular endothelial cells.” Journal of Biomedical Materials Research. 68A (4): 603-614, (2004)
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T.D. Dziubla, M.C. Torjman, J.I. Joseph, M. Murphy-Tatum and A.M. Lowman*, "Evaluation of porous networks of poly(2-hydroxyethyl methacrylate) as interfacial drug delivery devices." Biomaterials 22, 2893-2899, (2001)
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[[dziubla Lab|Home]]

Current revision

Resources

Protocols
Equipment

  • DLS
  • Glovebox
  • Fluorimeter
  • Freeze Dryer
  • Uv-Vis
  • GPC/HPLC

Materials
Internal

Contact

Thomas Dziubla
Assistant Professor
Mat and Chem Engineering
University of Kentucky
177 F Paul Anderson Tower
Lexington, KY 40506-0046
dziubla-at-engr.uky.edu

Thomas Dziubla

Assistant Professor
Department of Chemical and Materials Engineering
University of Kentucky

Education

Postdoctoral Fellow, Institute for Environmental Medicine, University of Pennsylvania, Philadelphia PA
PhD. Chemical Engineering, Drexel University, Philadelphia, PA
Honors B.S. Chemical Engineering', Purdue University, West Lafayette, IN


Awards and Honors

NIH NRSA Postdoctoral Fellow, Institute of Environmental Medicine
3rd Place Research Award: Molecular Design In Drug Discovery & Development Symposium Series(2004)
Biomaterials Annual Conference Travel Award:Honorable Mention(2003)
Drexel University Graduate Student Research Award(2001)
Mollye and Mitchell Glick Scholarship Award(2001)
American Institute of Chemists Award, Drexel University(2000)
Sigma Xi Research Day-Graduate Student Research Award(2000)
Drexel University Dean’s Fellowship Award(1998,1999)

Publications

M. Howard, X. Lu, J. Rinehart, M. Jay and T. Dziubla* “Physicochemical Characterization of Nanotemplate Engineered Solid Lipid Nanoparticles” Langmuir (Accepted)

J. Kim, M. Howard, T. Dziubla, J. Rinehart, M. Jay and X. Lu * “Uniformity of Drug Payload and its Effect on Stability of Solid Lipid Nanoparticles Containing an Ester Prodrug” ACS Nano (accepted)

J. Medley, Heisterberg J, and T Dziubla* “Synthesis and Characterization of CREKA-Targeted Polymers for the Disruption of Fibrin Gel Matrix Propagation.” J Biomater Sci:Poly Ed (E Pub 2010)

P. Wattamwar, Y. Mo, R. Wan, R. Palli, Q. Zhang and T. Dziubla*, “Antioxidant Activity of Degradable Polymer Poly(trolox ester) to Suppress Oxidative Stress Injury in the Cells.” Advanced Functional Materials 20:147-154 (2010)

Y Ma, Y Xiong*, J Zhai, H Zhu, and T Dziubla, “Fractionation and Evaluation of Radical Scavenging Peptides from in vitro Digests of Buckwheat Protein.” Food Chemistry 118:582-588 (2010)

J. Medley, E. Beane, E. Kaplan and T Dziubla* “Block copolymers for the rational design of self-forming postsurgical adhesion barriers.” Acta Biomaterialia 6:72-82 (2010)

E Simone*, T Dziubla, D Discher, and V Muzykantov. “Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase.” Biomacromolecules 10:1324-30 (2009)

E Simone*, T. Dziubla, E Arguiri, V Vardon, V Shuvaev, M Christofidou-Solomidou and V Muzykantov. “Loading PEG-catalase into filamentous and spherical polymer nanocarriers” Pharmaceutical Research 26:250-60 (2009)

E. Simone, T.D. Dziubla, and V. R Muzykantov., “Polymeric Carriers: Role of Geometry in Drug Delivery.” Expert Opinion on Drug Delivery 5:1283-1300 (2008)

M. Howard, M Jay, T. Dziubla, X. Lu*, “PEGylation of Nanocarrier Drug Delivery Systems: State of the Art.” J Biomed Nanotech 4:133-148 (2008)

C. Garnacho, R. Dhami, E. Simone, T. Dziubla, J. Leferovich, E. H. Schuchman, V. Muzykantov, and S. Muro*. “Delivery of acid sphingomyelinase in normal and Niemann-Pick disease mice using ICAM-1-targeted polymer nanoparticles” JPET 325:400-408 (2008)

T.D. Dziubla*, V.V. Shuvaev, N.K. Hong, B. Hawkins, M. Muniswamy, H. Takano, E. Simone, M.T. Nakada, A. Fisher, S.M. Albelda, and V.R. Muzykantov, “Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies.” Biomaterials 2:215-27 (2008)

E. Simone*, T. Dziubla, F. Colon, D. Discher and V.R. Muzykantov. “Amphiphilicity of PEG-PLA diblock copolymer controls the formulation and morphology of nanocarriers protecting loaded therapeutic enzyme from proteolysis” Biomacromolecules 8:3914-21 (2007)

S. Muro*, T.D. Dziubla, W. Qui, J. Leferovich, X. Cui, E. Berk and V.R. Muzykantov “Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to ICAM-1.” JPET 317(3):1161-9 (2006)

Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR. “Advanced drug delivery systems that target the vascular endothelium.” Mol Interv. 2:98-112 (2006)

T.D. Dziubla*, A. Karim and V. Muzykantov, “Polymer nanocarriers (PNC) protect loaded catalase cargo from proteolysis.” Journal of Controlled Release 102(2), 427-439, (2005)

T.D. Dziubla and A.M. Lowman*, “Vascularization of PEG-grafted macroporous hydrogel sponges: a 3-dimensional in vitro angiogenesis model utilizing human microvascular endothelial cells.” Journal of Biomedical Materials Research. 68A (4): 603-614, (2004)

T.D. Dziubla, M.C. Torjman, J.I. Joseph, M. Murphy-Tatum and A.M. Lowman*, "Evaluation of porous networks of poly(2-hydroxyethyl methacrylate) as interfacial drug delivery devices." Biomaterials 22, 2893-2899, (2001)


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