User:Thomas Dziubla

People Principal Investigator Graduate Students [show][hide] David Cochran Prachi Gupta Sundar Prasanth Andrew Vasilakes Paritosh Wattamwar Undergraduates [show][hide] James Mikael Johnson Taylor Kuhn Adam Lyvers --- Past Graduate Students [show][hide] John M. Medley Past Undergraduates [show][hide] Matt-Sean Alexander Katie Arambasick Kevin Baldridge Mark Bailey Sarah Bartsch Kala Bean Eric Beane Max Bezold Justin Byarski Karen Chan Jennifer Chen Kelly Cummings Kimberly Doan Bradlee Heckman John Heisterberg Tuan Ho Vance Jones Danielle LaValley Alex Lopez Tim Pittaluga Rachel Van Stelle Past High school Students [show][hide] David Parell

Research Research Overview Projects [show][hide] Antioxidant Polymers Adhesion Barriers Publications Links

Resources Protocols Equipment [show][hide] DLS Glovebox Fluorimeter Freeze Dryer Uv-Vis GPC/HPLC Materials Internal

Contact Thomas Dziubla Assistant Professor Mat and Chem Engineering University of Kentucky 177 F Paul Anderson Tower Lexington, KY 40506-0046 dziubla-at-engr.uky.edu

Thomas Dziubla

Thomas Dean Dziubla
177 F Paul Anderson Tower, Lexington KY 40506-0046
Work: (859) 257-4063•Cell: (859) 940-6113
Email: dziubla@engr.uky.edu

Academic Experience and Education:
July, 2006-Present University of Kentucky, Lexington, KY Assistant Professor, Department of Chemical and Materials Engineering
November, 2004-June 2006 University of Pennsylvania School of Medicine, Philadelphia, PA Research Associate, Institute for Environmental Medicine
November, 2002-November, 2004 University of Pennsylvania School of Medicine, Philadelphia, PA NIH NRSA Postdoctoral Fellowship Award

November, 2002 Drexel University, Philadelphia, PA PhD. Chemical Engineering
Purdue University, West Lafayette, IN Honors B.S. Chemical Engineering

Awards: 2004 3rd Prize, Poster Competition: Molecular Design In Drug Discovery & Development Symposium Series 2003 Annual Biomaterials Meeting Travel Award: Honorable Mention 2001 Drexel University Graduate Student Research Award 2001 Mollye and Mitchell Glick Scholarship Award 2000 American Institute of Chemists Award, Drexel University 2000 Sigma Xi Research Day-Graduate Student Research Award 1998, 1999 Drexel University Dean’s Fellowship Award
Publications: (* denotes corresponding author)

C. Garnacho, R. Dhami, E. Simone, T. Dziubla, J. Leferovich, E. H. Schuchman, V. Muzykantov, and S. Muro*. “Delivery of acid sphingomyelinase in normal and Niemann-Pick disease mice using ICAM-1-targeted polymer nanoparticles” JPET (In Revision)

T.D. Dziubla*, V.V. Shuvaev, N.K. Hong, B. Hawkins, M. Muniswamy, H. Takano, E. Simone, M.T. Nakada, A. Fisher, S.M. Albelda, and V.R. Muzykantov, “Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies.” Biomaterials 2:215-27 (2008)

E. Simone*, T. Dziubla, F. Colon, D. Discher and V.R. Muzykantov. “Amphiphilicity of PEG-PLA diblock copolymer controls the formulation and morphology of nanocarriers protecting loaded therapeutic enzyme from proteolysis” Biomacromolecules 8:3914-21 (2007)

S. Muro*, T.D. Dziubla, W. Qui, J. Leferovich, X. Cui, E. Berk and V.R. Muzykantov “Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to ICAM-1.” JPET 317(3):1161-9 (2006)

T.D. Dziubla*, A. Karim and V. Muzykantov, “Polymer nanocarriers (PNC) protect loaded catalase cargo from proteolysis.” Journal of Controlled Release 102(2), 427-439, (2005)

T.D. Dziubla and A.M. Lowman*, “Vascularization of PEG-grafted macroporous hydrogel sponges: a 3-dimensional in vitro angiogenesis model utilizing human microvascular endothelial cells.” Journal of Biomedical Materials Research. 68A (4): 603-614, (2004)

T.D. Dziubla, M.C. Torjman, J.I. Joseph, M. Murphy-Tatum and A.M. Lowman*, "Evaluation of porous networks of poly(2-hydroxyethyl methacrylate) as interfacial drug delivery devices." Biomaterials 22, 2893-2899, (2001)

Conference Proceedings
D. Besser, G. Swan, T. Dziubla and R. Eitel, “Building Continuous Loop Learning Communities: An Engineering Outreach Case Study” ASEE Southeast Spring Conference Proceedings (2008)
A.M. Lowman, T.D. Dziubla and N.A. Peppas, “Novel networks and gels containing increased amounts of grafted and crosslinked poly(ethylene glycol).” ACS Polymer Prepr., 38(1), (1997)
Book Chapters and Review Articles E. Simone, T. Dziubla, V Shuvaev and V.R. Muzykantov, “Synthesis and Characterization of Polymer Nanocarriers for Therapeutic Enzyme Delivery.” In:, 2nd Edition for Methods in Molecular Biology: Free Radicals and Antioxidant Protocols (In Press) Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR. “Advanced drug delivery systems that target the vascular endothelium.” Mol Interv. 2:98-112 (2006) T.D. Dziubla and V. Muzykantov, “Nanocarriers for drug delivery to the pulmonary vasculature.” In: Nanoparticulates as Drug Carriers, V Torchilin, Ed. Imperial College Press, London. (2006) T.D. Dziubla and V. Muzykantov, “Synthetic carriers for the delivery of protein therapeutics.” In: Biotechnology and Genetic Engineering Reviews Vol. 22., S.E. Harding Ed., Lavoisier Publishing, Paris, France 267-298 (2006) T. Dziubla, S. Muro, V. R. Muzykantov and M. Koval, “Nanoscale antioxidant therapeutics.” In: Oxidative Stress, Disease and Cancer, Keshav K. Singh, Ed. Imperial College Press, London. (2006) A.M. Lowman, T.D. Dziubla, P. Bures and N.A. Peppas, “Structural and dynamic response of neutral and intelligent networks in biomedical environments.” in N.A. Peppas and M.V. Sefton, eds., “Advances in Chemical Engineering Vol 29: Molecular and Cellular Foundations of Biomaterials.” Academic Press, New York, (2004) V. Shuvaev, T. Dziubla, R. Wiewrodt and V. Muzykantov, “Streptavidin-biotin cross-linking of therapeutic enzymes with carrier antibodies: nanoconjugates for protection against endothelial oxidative stress.” In: Methods in Molecular Biology V 283: Bioconjugation Protocols: Strategies and Methods, C.Niemeyer, Ed., Humana Press, (2004) T.D. Dziubla, M.C. Torjman, J.I. Joseph and A.M. Lowman, “Implantable drug delivery devices: design of a biomimetic interfacial drug delivery system.” In: Biomimetic Materials and Design: Interactive Biointerfacial Strategies, Tissue Engineering, and Targeted Drug Delivery, A K Dillow and A M Lowman, Eds., Marcel Dekker, (2003) T.D. Dziubla and A.M. Lowman, “Smart gels.” In: Encyclopedia of Smart Materials, M. Schwartz Ed. Wiley and Sons, (2001)