User:Timothy L. Foley: Difference between revisions
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==Contact Info== | ==Contact Info== | ||
Timothy L. Foley<BR> | |||
NIH Chemical Genomics Center/ NIH Center for Translational Therapeutics <BR> | |||
9800 Medical Center Drive<BR> | |||
Bldg B, rm 1022<BR> | |||
Bethesda, MD 20850 <BR> | |||
*[[Special:Emailuser/Timothy L. Foley|Email me through OpenWetWare]] | *[[Special:Emailuser/Timothy L. Foley|Email me through OpenWetWare]] | ||
I work in the [[Burkart]] Lab at University of California, San Diego | I just finished my graduate work in the [[Burkart]] Lab at University of California, San Diego; and am currently relocating to Washington, D.C. to start a postdoctoral position at the [http://www.ncgc.nih.gov/ '''NIH Chemical Genomics Center'''] | ||
<!--Include info about your educational background--> | <!--Include info about your educational background--> | ||
* 2010, PhD, Chemistry, University of California, San Diego | |||
* 2006, MS, Chemistry, University of California, San Diego | * 2006, MS, Chemistry, University of California, San Diego | ||
* 2004, BS, Cell Biology & Biochemistry, University of California, San Diego | * 2004, BS, Cell Biology & Biochemistry, University of California, San Diego | ||
| Line 19: | Line 18: | ||
==Research interests== | ==Research interests== | ||
<!-- Feel free to add brief descriptions to your research interests as well --> | <!-- Feel free to add brief descriptions to your research interests as well --> | ||
* Therapeutically active small molecules from Nature | |||
* Enzyme structure and function | |||
* Metabolic pathway engineering | |||
* New antibiotics | |||
* Neglected diseases | |||
* Chemical genetics | |||
* Chemical probe development | |||
* Bacterial cell wall assembly | |||
==Publications== | ==Publications== | ||
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed --> | <!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed --> | ||
<biblio> | <biblio> | ||
#mAb35 pmid=20836515 | |||
#DyeChem pmid=20725690 | |||
#LOPAC pmid=20094656 | |||
#anthanilate pmid=19895578 | |||
#laetirubin pmid=19842686 | |||
#OASIS pmid=19785476 | #OASIS pmid=19785476 | ||
#Assay_01 pmid=19573516 | #Assay_01 pmid=19573516 | ||
| Line 36: | Line 44: | ||
==Useful links== | ==Useful links== | ||
*[http://chem-faculty.ucsd.edu/burkart '''Burkart Lab Main Page'''] | *[http://chem-faculty.ucsd.edu/burkart '''Burkart Lab Main Page'''] | ||
*[http://www.ncgc.nih.gov/ '''NIH Chemical Genomics Center'''] | |||
*[http://mli.nih.gov/mli/ '''Molecular Libraries Program'''] | |||
*[[OpenWetWare:Welcome|Introductory tutorial]] | *[[OpenWetWare:Welcome|Introductory tutorial]] | ||
*[[Help|OpenWetWare help pages]] | *[[Help|OpenWetWare help pages]] | ||
*[[User:Timothy_L._Foley/Notebook| my open wetware notebooks]] | *[[User:Timothy_L._Foley/Notebook| my open wetware notebooks]] | ||
Latest revision as of 10:17, 21 November 2012
Contact Info
Timothy L. Foley
NIH Chemical Genomics Center/ NIH Center for Translational Therapeutics
9800 Medical Center Drive
Bldg B, rm 1022
Bethesda, MD 20850
I just finished my graduate work in the Burkart Lab at University of California, San Diego; and am currently relocating to Washington, D.C. to start a postdoctoral position at the NIH Chemical Genomics Center
- 2010, PhD, Chemistry, University of California, San Diego
- 2006, MS, Chemistry, University of California, San Diego
- 2004, BS, Cell Biology & Biochemistry, University of California, San Diego
Research interests
- Therapeutically active small molecules from Nature
- Enzyme structure and function
- Metabolic pathway engineering
- New antibiotics
- Neglected diseases
- Chemical genetics
- Chemical probe development
- Bacterial cell wall assembly
Publications
- Yu WL, Guizzunti G, Foley TL, Burkart MD, and La Clair JJ. An optimized immunoaffinity fluorescent method for natural product target elucidation. J Nat Prod. 2010 Oct 22;73(10):1659-66. DOI:10.1021/np100371k |
- Foley TL, Yasgar A, Garcia CJ, Jadhav A, Simeonov A, and Burkart MD. Preparation of FRET reporters to support chemical probe development. Org Biomol Chem. 2010 Oct 21;8(20):4601-6. DOI:10.1039/c0ob00322k |
- Yasgar A, Foley TL, Jadhav A, Inglese J, Burkart MD, and Simeonov A. A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase. Mol Biosyst. 2010 Feb;6(2):365-75. DOI:10.1039/b913291k |
- Foley TL, Young BS, and Burkart MD. Phosphopantetheinyl transferase inhibition and secondary metabolism. FEBS J. 2009 Dec;276(23):7134-45. DOI:10.1111/j.1742-4658.2009.07425.x |
- Lear MJ, Simon O, Foley TL, Burkart MD, Baiga TJ, Noel JP, DiPasquale AG, Rheingold AL, and La Clair JJ. Laetirobin from the parasitic growth of Laetiporus sulphureus on Robinia pseudoacacia. J Nat Prod. 2009 Nov;72(11):1980-7. DOI:10.1021/np9002838 |
- Meier JL, Niessen S, Hoover HS, Foley TL, Cravatt BF, and Burkart MD. An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis. ACS Chem Biol. 2009 Nov 20;4(11):948-57. DOI:10.1021/cb9002128 |
- Foley TL and Burkart MD. A homogeneous resonance energy transfer assay for phosphopantetheinyl transferase. Anal Biochem. 2009 Nov 1;394(1):39-47. DOI:10.1016/j.ab.2009.06.037 |
- Meier JL, Barrows-Yano T, Foley TL, Wike CL, and Burkart MD. The unusual macrocycle forming thioesterase of mycolactone. Mol Biosyst. 2008 Jun;4(6):663-71. DOI:10.1039/b801397g |
- Foley TL and Burkart MD. Site-specific protein modification: advances and applications. Curr Opin Chem Biol. 2007 Feb;11(1):12-9. DOI:10.1016/j.cbpa.2006.11.036 |
- La Clair JJ, Foley TL, Schegg TR, Regan CM, and Burkart MD. Manipulation of carrier proteins in antibiotic biosynthesis. Chem Biol. 2004 Feb;11(2):195-201. DOI:10.1016/j.chembiol.2004.02.010 |
