User:Tong Zhou

Tong Zhou

Tong Zhou, Research Assistant Professor
Institute for Personalized Respiratory Medicine
Section of Pulmonary, Critical Care, and Sleep Medicine
Department of Medicine
The University of Illinois at Chicago, Chicago, Illinois 60612
Email: tongzhou@uic.edu, Tel: 312-355-5933

Former Position

• 2006 - 2010, Postdoc, Center for Computational Biology and Bioinformatics and Section of Integrative Biology, The University of Texas at Austin

Education

• 2006, PhD, Southeast University, China
• 2002, MS, Southeast University, China
• 2000, BS, Southeast University, China

Research interests

1. Computational Biology
2. Bioinformatics
3. Translational Genomics and Genetics

Publications

• 2013

1. Mathew B., Jacobson J.R., Siegler J.H., Moitra J., Blasco M., Xie L.S., Unzueta C., Zhou T., Evenoski C., Al-Sakka M., Sharma R., Huey B., Bulent A., Smith B., Sundararajan J., Reddy N.M., Reddy S.P., Dudek S.M., Natarajan V., Weichselbaum R.R., and Garcia J.G.N., Role of MIF in age-related susceptibility to radiation lung injury via Nrf2 and antioxidant regulation. Am. J. Respir. Cell Mol Biol., 49, 269-278, 2013.
2. Gu W., Wang X., Zhai C., Zhou T.*, Xie X., Biological basis of miRNA action when their targets are located in human protein coding region. PLoS ONE, 8, e63403, 2013. (*co-corresponding author)
3. Huang L.S., Berdyshev E., Mathew B., Fu P., Gorshkova I.A., He D., Ma W., Noth I., Ma S.F., Pendyala S., Reddy S.P., Zhou T., Zhang W., Garzon S.A., Garcia J.G.N., and Natarajan V. Targeting Sphingosine Kinase 1 attenuates bleomycin-induced pulmonary fibrosis. FASEB J., 27, 1749-1760, 2013.

• 2012

1. Sun X., Singleton P.A., Letsiou E., Zhao J., Belvitch P., Sammani S., Chiang E.T., Moreno-Vinasco L., Wade M.S., Zhou T., Liu B., Parastatidis I., Thomson L., Ischiropoulos H., Natarajan V., Jacobson J.R., Machado R.F., Dudek S.M., and Garcia J.G., Sphingosine-1-phosphate receptor 3 is a novel biomarker in acute lung injury. Am. J. Respir. Cell Mol. Biol., 47, 628-636, 2012.
2. Pitroda S.P., Zhou T.*, Sweis R.F., Filippo M., Labay E., Beckett M.A., Mauceri H.J., Liang H., Darga T.E., Perakis S., Khan S.A., Sutton H.G., Zhang W., Khodarev N.N., Garcia J.G.N., and Weichselbaum R.R., Tumor endothelial inflammation predicts clinical outcome in diverse human cancers. PLoS ONE, 7, e46104, 2012. (*co-first author)
3. Zhou T., Ko E.A.*, Gu W., Lim I., Bang H., and Ko J.H., Non-silent story on synonymous sites in voltage-gated ion channel genes. PLoS ONE, 7, e48541, 2012.
4. Gu W., Wang X., Zhai C., Xie X., and Zhou T.*, Selection on synonymous sites for increased accessibility around miRNA binding sites in plants. Mol. Biol. Evol., 29, 3037-3044, 2012. (*corresponding author)
5. Gu W., Wang X., Zhai C., Xie X., Parinandi G., and Zhou T.*, Translation efficiency in upstream region of microRNA targets in Arabidopsis thaliana. Evol. Bioinform., 8, 565-574, 2012. (*corresponding author)
6. Zhou T., Zhang W., Sweiss N.J., Chen E.S., Moller D.R., Knox K.S., Ma S.F., Wade M.S., Noth I., Machado R.F., and Garcia J.G.N., Peripheral blood gene expression as a novel genomic biomarker in complicated sarcoidosis. PLoS ONE, 7, e44818, 2012.
7. Frank K.M., Zhou T., Moreno-Vinasco L., Hollett B., Garcia J.G.N., and Wardenburg J.B., Host response signature to Staphylococcus aureus α-hemolysin implicates pulmonary TH17 response. Infection and Immunity, 80, 3161-3169, 2012.
8. Desai A.A., Zhou T., Ahmad H., Zhang W., Mu W., Trevino S., Wade M.S., Raghavachari N., Kato G.J., Peters-Lawrence M., Thiruvoipati T., Turner K., Artz N., Huang Y., Patel A.R., Yuan J.X., Gordeuk V.R., Lang R.M., Garcia J.G.N., and Machado R.F., A novel molecular signature for elevated tricuspid regurgitation velocity in sickle cell disease. Am. J. Respir. Crit. Care. Med., 186, 359-368, 2012.
9. Gorshkova I., Zhou T., Mathew B., Jacobson J.R., Takekoshi D., Bhattacharya P., Smith B., Aydogan B., Weichselbaum R.R., Natarajan V., Garcia J.G., and Berdyshev E.V., Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression. J. Lipid Res., 53, 1553-1568, 2012.
10. Mekontso Dessap A., Voiriot G., Zhou T., Marcos E., Dudek S.M., Jacobson J.R., Machado R., Adnot S., Brochard L., Maitre B., and Garcia J.G., Conflicting Physiological and Genomic Cardiopulmonary Effects of Recruitment Maneuvers in Murine Acute Lung Injury. Am. J. Respir. Cell Mol. Biol., 46, 541-550, 2012.

• 2011

1. Mathew B., Jacobson J.R., Berdyshev E., Huang Y., Sun X., Zhao Y., Gerhold L.M., Siegler J., Evenoski C., Wang T., Zhou T., Zaidi R., Moreno-Vinasco L., Bittman R., Chen C.T., Lariviere P.J., Sammani S., Lussier Y.A., Dudek S.M., Natarajan V., Weichselbaum R.R., and Garcia J.G., Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs. FASEB J., 25, 3388-3400, 2011.
2. Ma S.F., Xie L., Pino-Yanes M., Sammani S., Wade M.S., Letsiou E., Siegler J., Wang T., Infusino G., Kittles R.A., Flores C., Zhou T., Prabhakar B.S., Moreno-Vinasco L., Villar J., Jacobson J.R., Dudek S.M., and Garcia J.G., Type 2 Deiodinase and host responses of sepsis and acute lung injury. Am. J. Respir. Cell Mol. Biol., 45, 1203-1211, 2011.
3. Sammani S., Park K.S., Zaidi S.R., Mathew B., Wang T., Huang Y., Zhou T., Lussier Y.A., Husain A.N., Moreno-Vinasco L., Vigneswaran W.T., and Garcia J.G., A sphingosine 1-phosphate 1 receptor agonist modulates brain death-induced neurogenic pulmonary injury. Am. J. Respir. Cell Mol. Biol., 45, 1022-1027, 2011.
4. Ramsey D.C., Scherrer M.P., Zhou T., and Wilke C.O., The relationship between relative solvent accessibility and evolutionary rate in protein evolution. Genetics, 188, 479-488, 2011.
5. Zhou T. and Wilke C.O., Reduced stability of mRNA secondary-structure near the translation-initiation site in dsDNA viruses. BMC Evol. Biol., 11, 59, 2011.
6. Zhou T., Garcia J.G.N., and Zhang W., Integrating microRNAs into a system biology approach to acute lung injury. Transl. Res., 157, 180-190, 2011.

1. Lee_et_al_2010 pmid=21046618
2. Zhou_et_al_2010 pmid=20231333
3. Novella_et_al_2010 pmid=20181701
4. Gu_et_al_2010 pmid=20140241

//The first two authors contributed equally to this work Featured in GenomeWeb Daily Scan

1. Zhou_et_al_2009 pmid=19349643
2. Zhou_et_al_2008a pmid=19018282
3. Zhou_et_al_2008b pmid=18379715
4. Zhou_et_al_2006a pmid=16640774
5. Zhou_et_al_2006b pmid=16380221
6. Zhou_et_al_2005a pmid=17281312
7. Zhou_et_al_2005b pmid=15917130
8. Gu_et_al_2004a pmid=15041183
9. Gu_et_al_2004b pmid=15013221
10. Gu_et_al_2003 pmid=15376949
11. Ma_et_al_2002 pmid=12069729

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