User:Tyler Reddy

Tyler Reddy - Curriculum Vitae

Department of Biochemistry & Molecular Biology
Dalhousie University
Sir Charles Tupper Medical Building
5850 College St.
Halifax, Nova Scotia B3H 1X5
Canada

Email: treddy@dal.ca

Education

Dalhousie University, Halifax, Nova Scotia (2001 – 2005).

B.Sc. – Honours Biochemistry and Molecular Biology
(Conferred May 2005 with First Class Honours)
Thesis : Mandelate racemase inhibitors: testing pentafluoromandelate
and conformationally restricted hydroxamates.
Supervisor : Dr. Stephen Bearne.

Fellowships & Awards

Graduate

• Renewal: Izaak Walton Killam Memorial Scholarship Level 2 (2010-2011)
• NSERC Canada Graduate Scholarships – Michael Smith Foreign Study Supplement - University of Oxford (2010)
• Faculty of Medicine Poster Presentation Award, Graduate Student Research Day, Dalhousie University (2009).
  
• The President's Award, Dalhousie University (2009).
  
• Natural Sciences and Engineering Research Council of Canada: Canada Graduate Scholarship D (CGS D) (2009).
  
• One of only three students nominated by Dalhousie University for an NSERC Vanier CGS D (2009).
  
• Honourary Killam Scholar, Izaak Walton Killam Predoctoral Scholarship, Dalhousie University (2009).
  
• Faculty of Graduate Studies Conference Travel Grant, Dalhousie University (2008).
  
• Travel Award, Chemical Biophysics Symposium Committee, University of Toronto (2008).
  
• Natural Sciences and Engineering Research Council of Canada: Canada Graduate Scholarship M (CGS M) (2008).
  
• Nova Scotia Health Research Foundation: Student Research Capacity Award (2007).
  
• Killam pre-doctoral fellowship, Dalhousie University (2005).
  
• Natural Sciences and Engineering Research Council of Canada: Canada Graduate Scholarship M (CGS M) (2005).
  

Undergraduate

• University Medal in Biochemistry, Dalhousie University (2005).
  
• Peter Dolphin Memorial Prize in Biochemistry, Dalhousie University (2005).
  
• Society of Chemical Industry Science Award, Dalhousie University (2005).
  
• Dalhousie In Course Scholarship, Dalhousie University (2004).
  
• Natural Sciences and Engineering Research Council of Canada: Undergraduate Student Research Award (USRA) (2004)
  
• Ross Stewart Smith Scholarship, Dalhousie University (2003).
  
• Natural Sciences and Engineering Research Council of Canada: Undergraduate Student Research Award (USRA) (2003)
  
• Natural Sciences and Engineering Research Council of Canada: Undergraduate Student Research Award (USRA) (2002)
  

Secondary

• Renewable Entrance Scholarship, Dalhousie University (2001).
  
• Governor General’s Academic Medal, Dartmouth High School (2001).
  
• DHS mathematics award, Dartmouth High School (2001).
  
• University of Toronto National Book Award, Dartmouth High School (2001).
  
• Lieutenant Governor’s Academic Medal, Dartmouth High School (2000).
  

Publications

*Equal contributions

• Reddy, T., Li, X., Fliegel, L., Sykes, B.D., and Rainey, J.K. (2010) Correlating structure, dynamics, and function in transmembrane segment VII of the Na+/H+ exchanger isoform 1. Biochim Biophys Acta: Biomembranes. 1798: 94-104.  Pubmed

• Reddy, T. and Rainey, J.K. (2010) Interpretation of biomolecular NMR spin relaxation parameters. Biochemistry and Cell Biology. 88: 131-142.  Pubmed

• Langelaan, D.N., Bebbington, E.M., Reddy, T., and Rainey, J.K. (2009) Structural insight into G-protein coupled receptor binding by apelin. Biochemistry. 48: 537-548.  Pubmed

• Reddy, T.*, Ding, J.*, Li, X., Sykes, B.D., Rainey, J.K., and Fliegel, L. (2008) Structural and Functional Characterization of Transmembrane Segment IX of the NHE1 Isoform of the Na+/H+ Exchanger. Journal of Biological Chemistry. 283: 22018-22030.  Pubmed  PDB entry (2K3C)  BMRB entry (15747)

• Baguma-Nibasheka, M., Reddy, T., Abbas-Butt, A., and Kablar, B. (2006) Fetal ocular movements and retinal cell differentiation: analysis employing DNA microarrays. Histology and histopathology. 21: 1331-1337.  Pubmed

• Reddy, T.*, Rot-Nikcevic, I.*, Downing, K.J., Belliveau, A.C., Hallgrímsson, B., Hall, B.K., and Kablar, B. (2006) Myf5-/-: MyoD-/- amyogenic fetuses reveal the importance of early contraction and static loading by striated muscle in mouse skeletogenesis. Development genes and evolution. 216: 1-9.  Pubmed

• Reddy, T. and Kablar, B. (2004) Evidence for the involvement of neurotrophins in muscle transdifferentiation and acetylcholine receptor transformation in the esophagus of Myf5-/-:MyoD-/- and NT-3-/- embryos. Developmental Dynamics. 231: 683-692.  Pubmed

Conference Presentations and Invited Talks

Primary presenter underlined

• Reddy, T., Sykes, B.D., and Rainey, J.K. (2009) 15N backbone NMR relaxation studies of transmembrane segment VII of the Na+/H+ exchanger isoform 1. Nuclear Magnetic Resonance Research Resource (NMR3) 4th Annual Fall Workshop, Dalhousie University, Halifax, NS. (Poster)
  

• Reddy, T., Sykes, B.D., and Rainey, J.K. (2009) Correlating Structure, Dynamics, and Function in Transmembrane Segment VII of the Na+/H+ Exchanger Isoform 1. 52nd Annual Meeting of the CSBMCB, Niagara-on-the-Lake, Ontario. (Poster)
  

• Reddy, T., Sykes, B.D., and Rainey, J.K. (2009) 15N relaxation analysis of the Na+/H+ exchanger isoform 1 transmembrane segment VII. Graduate Student Research Day, Dalhousie University, Halifax, NS. (Poster)
  

• Reddy, T., Sykes, B.D., and Rainey, J.K. (2009) Model-free analysis and reduced spectral density mapping of a micelle-solubilized peptide using 15N relaxation data. Chemical Biophysics Symposium, Toronto, ON. (Poster)
  

• Reddy, T. (2009) Kinky Peptides: 15N Backbone NMR Relaxation Studies of a Na+/H+ Exchanger Isoform 1 Transmembrane Segment. Chemical Biology and Chemical Biophysics Networking Retreat, Halifax, NS. (Oral presentation)
  

• Reddy, T. (2008) Structure and Dynamics of Na+/H+ Exchanger Isoform 1 (NHE1) Transmembrane Segments. 3rd Annual Atlantic Region Magnetic Resonance Centre NMR Spectroscopy Workshop, Halifax, NS. (Oral presentation)
  

• Reddy, T. (2008) Structural study of the Na+/H+ exchanger isoform 1 (NHE1) transmembrane segment IX in micelles. Biochemistry 640--Biomembranes Discussion Group, University of Alberta, Edmonton, AB. (Invited talk)

• Reddy, T., Ding, J., Li, X., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Correlating structure and function for transmembrane segment IX of the human Na+/H+ exchanger isoform 1. XXIIIrd International Conference on Magnetic Resonance in Biological Systems (ICMRBS), San Diego, CA. (Poster)

• Rainey, J.K., Langelaan, D.N., and Reddy, T. (2008) Detecting and Dealing With Conformational Sampling in Peptides. XXIIIrd International Conference on Magnetic Resonance in Biological Systems (ICMRBS), San Diego, CA. (Poster)

• Lemieux, M.J., Lamoureux, J., Mak, M., Fischer, S., Rainey, J.K., Reddy, T., and James, M. (2008) Structural and Functional Studies of the Rhomboid Intramembrane Peptidase from H. influenzae. The 22nd Annual Symposium of the Protein Society, San Diego, CA. (Poster)
  

• Reddy, T., Ding, J., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Structural and Functional Characterization of Transmembrane Segment IX of the Na+/H+ Exchanger Isoform 1. Graduate Student Research Day, Dalhousie University, Halifax, NS. (Poster)
  

• Langelaan, D.N., Bebbington, E.M., Reddy, T., and Rainey, J.K. (2008) NMR, circular dichroism & fluorescence spectroscopy provide insight into conformational sampling of apelin. Graduate Student Research Day, Dalhousie University, Halifax, NS. (Poster)
  

• Reddy, T., Ding, J., Li, X., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Structure and topology of transmembrane segment IX of the human Na+/H+ exchanger isoform 1. 33rd Annual APICS/CIC Undergraduate Chemistry Conference, Halifax, NS. (Oral presentation)
  

• Langelaan, D.N., Bebbington, E.M., Reddy, T., and Rainey, J.K. (2008) Structure in a Random Coil Peptide: The Apelin Story. 33rd Annual APICS/CIC Undergraduate Chemistry Conference, Halifax, NS. (Poster)
  

• Reddy, T., Ding, J., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Structural and functional characterization of transmembrane segment IX of the Na+/H+ exchanger isoform 1. Chemical Biophysics Symposium, Toronto, ON. (Poster)
  

• Langelaan, D.N., Bebbington, E.M., Reddy, T., and Rainey, J.K. (2008) NMR, circular dichroism & fluorescence spectroscopy provide insight into the random-coil nature of apelin peptides. Chemical Biophysics Symposium, Toronto, ON. (Poster)
  

• Langelaan, D.N., Bebbington, E.M., Reddy, T., Grant, M., and Rainey, J.K. (2008) Conformational sampling by apelin peptides gives functional insight. Joint 52nd Annual Meeting of the Biophysical Society & 16th IUPAB International Biophysics Congress, Long Beach, CA. (Poster)
  

• Reddy, T. and Rainey, J.K. (2007) NMR of transmembrane peptides. Atlantic Region Magnetic Resonance Centre NMR Spectroscopy Workshop, Halifax, NS. (Poster)
  

• Kablar, B. and Reddy, T. (2004) The Role of Neurotrophins in the Esophageal Skeletal Muscle Transdifferentiation and Acetylcholine Receptor Transition. Society for Developmental Biology 63rd Annual Meeting, Calgary, AB. Developmental Biology. 271: 624. (Poster)
  

Upcoming Conference Presentations and Invited Talks

Primary presenter underlined

Teaching Assistantships

• Biochemistry for Pharmacy Students, Laboratory Instruction and Grading, Department of Biochemistry and Molecular Biology, Dalhousie University (2008).

• Biochemistry for Nursing Students and Introductory Biochemistry, Assignment and Midterm Grading, Department of Biochemistry and Molecular Biology, Dalhousie University (2008).

• Developmental Biology, Laboratory Instruction and Grading, Department of Biology, Dalhousie University (2005).

• Developmental Biology, Laboratory Instruction and Grading, Department of Biology, Dalhousie University (2004).

Training Camps

• Sun Microsystems Application Tuning Seminar, Halifax, Nova Scotia, Canada (2009).

• Nuclear Magnetic Resonance (NMR) Boot Camp, The National High Field Nuclear Magnetic Resonance Centre (NANUC), Edmonton, Alberta, Canada (2007).

• Canadian Forces Leadership and Recruit School, St-Jean-Sur-Richelieu, Quebec, Canada (2007).