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| = Tyler Reddy - Curriculum Vitae =
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| <font face="helvetica" size="3" style="color:#000000">
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| [http://www.biochem.dal.ca Department of Biochemistry & Molecular Biology]<br>
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| [http://www.dal.ca Dalhousie University] <br>
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| Sir Charles Tupper Medical Building<br>
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| 5850 College St.<br>
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| Halifax, Nova Scotia B3H 1X5 <br>
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| Canada<br>
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| Email: treddy@dal.ca
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| </font>
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| ==Education==
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| <font face="helvetica" size="3" style="color:#000000">
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| [http://www.dal.ca Dalhousie University], Halifax, Nova Scotia (2001 – 2005).
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| B.Sc. – Honours Biochemistry and Molecular Biology<br>
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| (Conferred May 2005 with First Class Honours)<br>
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| Thesis : Mandelate racemase inhibitors: testing pentafluoromandelate<br>
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| and conformationally restricted hydroxamates.<br>
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| Supervisor : Dr. Stephen Bearne.<br>
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| </font>
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| <!--Actual written thesis title: 'Mandelate racemase inhibitors: testing pentafluoromandelate and conformationally restricted hydroxamates -->
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| ==Fellowships & Awards==
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| <font face="helvetica" size="3" style="color:#000000">
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| ===Graduate===
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| *''[http://www.nserc.ca Natural Sciences and Engineering Research Council of Canada]: Canada Graduate Scholarship D (CGS D) (2009).''<br>
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| *''One of only three students nominated by Dalhousie University for an [http://www.vanier.gc.ca/ NSERC Vanier CGS D] (2009).''<br>
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| *''Honourary Killam Scholar, Izaak Walton Killam Predoctoral Scholarship, Dalhousie University (2009).''<br>
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| *''Faculty of Graduate Studies Conference Travel Grant, Dalhousie University (2008).''<br>
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| *''Travel Award, Chemical Biophysics Symposium Committee, University of Toronto (2008).''<br>
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| *''[http://www.nserc.ca Natural Sciences and Engineering Research Council of Canada]: Canada Graduate Scholarship M (CGS M) (2008).''<br>
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| *''Nova Scotia Health Research Foundation: Student Research Capacity Award (2007).''<br>
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| *''Killam pre-doctoral fellowship, Dalhousie University (2005).''<br>
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| *''[http://www.nserc.ca Natural Sciences and Engineering Research Council of Canada]: Canada Graduate Scholarship M (CGS M) (2005).''<br>
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| ===Undergraduate===
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| *''University Medal in Biochemistry, Dalhousie University (2005).''<br>
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| *''Peter Dolphin Memorial Prize in Biochemistry, Dalhousie University (2005).''<br>
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| *''Society of Chemical Industry Science Award, Dalhousie University (2005).''<br>
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| *''Dalhousie In Course Scholarship, Dalhousie University (2004).''<br>
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| *''[http://www.nserc.ca Natural Sciences and Engineering Research Council of Canada]: Undergraduate Student Research Award (USRA) (2004)''<br>
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| *''Ross Stewart Smith Scholarship, Dalhousie University (2003).''<br>
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| *''[http://www.nserc.ca Natural Sciences and Engineering Research Council of Canada]: Undergraduate Student Research Award (USRA) (2003)''<br>
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| *''[http://www.nserc.ca Natural Sciences and Engineering Research Council of Canada]: Undergraduate Student Research Award (USRA) (2002)''<br>
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| ===Secondary===
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| *''Renewable Entrance Scholarship, Dalhousie University (2001).''<br>
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| *''Governor General’s Academic Medal, Dartmouth High School (2001).''<br>
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| *''DHS mathematics award, Dartmouth High School (2001).''<br>
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| *''University of Toronto National Book Award, Dartmouth High School (2001).''<br>
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| *''Lieutenant Governor’s Academic Medal, Dartmouth High School (2000).''<br>
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| </font>
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| ==Publications==
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| <font face="helvetica" size="3" style="color:#000000">
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| <nowiki>*</nowiki>Equal contributions
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| *Langelaan, D.N., Bebbington, E.M., '''Reddy, T.''', and Rainey, J.K. (2009) Structural insight into G-protein coupled receptor binding by apelin. ''Biochemistry''. '''48''': 537-548. [http://www.ncbi.nlm.nih.gov/pubmed/19123778 Pubmed]
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| *'''Reddy, T.'''*, Ding, J.*, Li, X., Sykes, B.D., Rainey, J.K., and Fliegel, L. (2008) Structural and Functional Characterization of Transmembrane Segment IX of the NHE1 Isoform of the Na+/H+ Exchanger. ''Journal of Biological Chemistry''. '''283''': 22018-22030. [http://www.ncbi.nlm.nih.gov/pubmed/18508767 Pubmed] [http://www.rcsb.org/pdb/explore.do?structureId=2K3C PDB entry (2K3C)] [http://www.bmrb.wisc.edu/data_library/generate_summary.php?bmrbId=15747&chooseAccOrDep=useAcc BMRB entry (15747)]
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| *Baguma-Nibasheka, M., '''Reddy, T.''', Abbas-Butt, A., and Kablar, B. (2006) Fetal ocular movements and retinal cell differentiation: analysis employing DNA microarrays. ''Histology and histopathology''. '''21''': 1331-1337. [http://www.ncbi.nlm.nih.gov/pubmed/16977584 Pubmed]
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| *Rot-Nikcevic, I.*, '''Reddy, T.'''*, Downing, K.J., Belliveau, A.C., Hallgrímsson, B., Hall, B.K., and Kablar, B. (2006) Myf5-/-: MyoD-/- amyogenic fetuses reveal the importance of early contraction and static loading by striated muscle in mouse skeletogenesis. ''Development genes and evolution''. '''216''': 1-9. [http://www.ncbi.nlm.nih.gov/pubmed/16208536 Pubmed]
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| *'''Reddy, T.''' and Kablar, B. (2004) Evidence for the involvement of neurotrophins in muscle transdifferentiation and acetylcholine receptor transformation in the esophagus of Myf5-/-:MyoD-/- and NT-3-/- embryos. ''Developmental Dynamics''. '''231''': 683-692. [http://www.ncbi.nlm.nih.gov/pubmed/15497153 Pubmed]
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| </font>
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| ==Conference Presentations and Invited Talks==
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| <font face="helvetica" size="3" style="color:#000000">
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| Primary presenter underlined
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| *<u>'''Reddy, T.'''</u>, Sykes, B.D., and Rainey, J.K. (2009) Model-free analysis and reduced spectral density mapping of a micelle-solubilized peptide using 15N relaxation data. ''Chemical Biophysics Symposium'', Toronto, ON. ''(Poster)''<br>
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| *<u>'''Reddy, T.'''</u> (2009) Kinky Peptides: 15N Backbone NMR Relaxation Studies of a Na+/H+ Exchanger Isoform 1 Transmembrane Segment. ''Chemical Biology and Chemical Biophysics Networking Retreat'', Halifax, NS. ''(Oral presentation)''<br>
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| *<u>'''Reddy, T.'''</u> (2008) Structure and Dynamics of Na+/H+ Exchanger Isoform 1 (NHE1) Transmembrane Segments. ''3rd Annual Atlantic Region Magnetic Resonance Centre NMR Spectroscopy Workshop'', Halifax, NS. ''(Oral presentation)''<br>
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| *<u>'''Reddy, T.'''</u> (2008) Structural study of the Na+/H+ exchanger isoform 1 (NHE1) transmembrane segment IX in micelles. ''Biochemistry 640--Biomembranes Discussion Group'', University of Alberta, Edmonton, AB. ''(Invited talk)''
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| *<u>'''Reddy, T.'''</u>, Ding, J., Li, X., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Correlating structure and function for transmembrane segment IX of the human Na+/H+ exchanger isoform 1. ''XXIIIrd International Conference on Magnetic Resonance in Biological Systems (ICMRBS)'', San Diego, CA. ''(Poster)''
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| *<u>Rainey, J.K.</u>, Langelaan, D.N., and '''Reddy, T.''' (2008) Detecting and Dealing With Conformational Sampling in Peptides. ''XXIIIrd International Conference on Magnetic Resonance in Biological Systems (ICMRBS)'', San Diego, CA. ''(Poster)''
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| *<u>Lemieux, M.J.</u>, Lamoureux, J., Mak, M., Fischer, S., Rainey, J.K., '''Reddy, T.''', and James, M. (2008) Structural and Functional Studies of the Rhomboid Intramembrane Peptidase from ''H. influenzae''. ''The 22nd Annual Symposium of the Protein Society'', San Diego, CA. ''(Poster)''<br>
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| *<u>'''Reddy, T.'''</u>, Ding, J., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Structural and Functional Characterization of Transmembrane Segment IX of the Na+/H+ Exchanger Isoform 1. ''Graduate Student Research Day, Dalhousie University'', Halifax, NS. ''(Poster)''<br>
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| *<u>Langelaan, D.N.</u>, Bebbington, E.M., '''Reddy, T.''', and Rainey, J.K. (2008) NMR, circular dichroism & fluorescence spectroscopy provide insight into conformational sampling of apelin. ''Graduate Student Research Day, Dalhousie University'', Halifax, NS. ''(Poster)''<br>
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| *<u>'''Reddy, T.'''</u>, Ding, J., Li, X., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Structure and topology of transmembrane segment IX of the human Na+/H+ exchanger isoform 1. ''33rd Annual APICS/CIC Undergraduate Chemistry Conference'', Halifax, NS. ''(Oral presentation)''<br>
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| *<u>Langelaan, D.N.</u>, Bebbington, E.M., '''Reddy, T.''', and Rainey, J.K. (2008) Structure in a Random Coil Peptide: The Apelin Story. ''33rd Annual APICS/CIC Undergraduate Chemistry Conference'', Halifax, NS. ''(Poster)''<br>
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| *<u>'''Reddy, T.'''</u>, Ding, J., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Structural and functional characterization of transmembrane segment IX of the Na+/H+ exchanger isoform 1. ''Chemical Biophysics Symposium'', Toronto, ON. ''(Poster)''<br>
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| *<u>Langelaan, D.N.</u>, Bebbington, E.M., '''Reddy, T.''', and Rainey, J.K. (2008) NMR, circular dichroism & fluorescence spectroscopy provide insight into the random-coil nature of apelin peptides. ''Chemical Biophysics Symposium'', Toronto, ON. ''(Poster)''<br>
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| *Langelaan, D.N., Bebbington, E.M., '''Reddy, T.''', Grant, M., and <u>Rainey, J.K.</u> (2008) Conformational sampling by apelin peptides gives functional insight. ''Joint 52nd Annual Meeting of the Biophysical Society & 16th IUPAB International Biophysics Congress'', Long Beach, CA. ''(Poster)''<br>
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| *<u>'''Reddy, T.'''</u> and Rainey, J.K. (2007) NMR of transmembrane peptides. ''Atlantic Region Magnetic Resonance Centre NMR Spectroscopy Workshop'', Halifax, NS. ''(Poster)''<br>
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| *<u>Kablar, B.</u> and '''Reddy, T.''' (2004) The Role of Neurotrophins in the Esophageal Skeletal Muscle Transdifferentiation and Acetylcholine Receptor Transition. ''Society for Developmental Biology 63rd Annual Meeting'', Calgary, AB. ''Developmental Biology''. '''271''': 624. ''(Poster)''<br>
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| </font>
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| ==Upcoming Conference Presentations and Invited Talks==
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| <font face="helvetica" size="3" style="color:#000000">
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| Primary presenter underlined
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| *<u>'''Reddy, T.'''</u>, Sykes, B.D., and Rainey, J.K. (2009) 15N relaxation analysis of the Na+/H+ exchanger isoform 1 transmembrane segment VII. ''Graduate Student Research Day, Dalhousie University'', Halifax, NS. ''(Poster)''<br>
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| *<u>'''Reddy, T.'''</u>, Sykes, B.D., and Rainey, J.K. (2009) Correlating Structure, Dynamics, and Function in Transmembrane Segment VII of the Na+/H+ Exchanger Isoform 1. ''52nd Annual Meeting of the CSBMCB,'' Niagara-on-the-Lake, Ontario. ''(Poster)''<br>
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| </font>
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| ==Teaching Assistantships==
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| <font face="helvetica" size="3" style="color:#000000">
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| *''Biochemistry for Pharmacy Students, Laboratory Instruction and Grading, Department of Biochemistry and Molecular Biology, Dalhousie University (2008).''
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| *''Biochemistry for Nursing Students and Introductory Biochemistry, Assignment and Midterm Grading, Department of Biochemistry and Molecular Biology, Dalhousie University (2008).''
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| *''Developmental Biology, Laboratory Instruction and Grading, Department of Biology, Dalhousie University (2005).''
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| *''Developmental Biology, Laboratory Instruction and Grading, Department of Biology, Dalhousie University (2004).''
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| </font>
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| ==Training Camps==
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| <font face="helvetica" size="3" style="color:#000000">
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| *<u>''Nuclear Magnetic Resonance (NMR) Boot Camp</u>, The National High Field Nuclear Magnetic Resonance Centre (NANUC), Edmonton, Alberta, Canada (2007).''
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| *<u>''Canadian Forces Leadership and Recruit School</u>, St-Jean-Sur-Richelieu, Quebec, Canada (2007).''
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| </font>
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