User:Tyler Reddy

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*<u>'''Reddy, T.'''</u> (2010) Molecular dynamics simulations of the FGFR3 transmembrane domain and the spitz-rhomboid system. ''Structural Bioinformatics & Computational Biochemistry Unit Seminars'', Department of Biochemistry, University of Oxford, Oxford, United Kingdom. ''(Invited talk)''<br>
 
*<u>'''Reddy, T.'''</u>, Hall, B., Chetwynd, A., and Sansom, M.S.P. (2011) Molecular Dynamics Simulations of the Transmembrane Helix of the FGFR3 Receptor in POPC and DPPC. ''Biophysical Society 55th Annual Meeting,'' Baltimore Convention Centre, Baltimore, Maryland, U.S.A ''(Poster?)''  
*<u>'''Reddy, T.'''</u>, Hall, B., Chetwynd, A., and Sansom, M.S.P. (2011) Molecular Dynamics Simulations of the Transmembrane Helix of the FGFR3 Receptor in POPC and DPPC. ''Biophysical Society 55th Annual Meeting,'' Baltimore Convention Centre, Baltimore, Maryland, U.S.A ''(Poster?)''  

Revision as of 09:58, 21 October 2010

Contents

Tyler Reddy - Curriculum Vitae

Department of Biochemistry & Molecular Biology
Dalhousie University
Sir Charles Tupper Medical Building
5850 College St.
Halifax, Nova Scotia B3H 1X5
Canada

Email: treddy@dal.ca

Education

Dalhousie University, Halifax, Nova Scotia (2001 – 2005).

B.Sc. – Honours Biochemistry and Molecular Biology
(Conferred May 2005 with First Class Honours)
Thesis : Mandelate racemase inhibitors: testing pentafluoromandelate
and conformationally restricted hydroxamates.
Supervisor : Dr. Stephen Bearne.

Fellowships & Awards

Graduate

Undergraduate

Secondary

  • Renewable Entrance Scholarship, Dalhousie University (2001).
  • Governor General’s Academic Medal, Dartmouth High School (2001).
  • DHS mathematics award, Dartmouth High School (2001).
  • University of Toronto National Book Award, Dartmouth High School (2001).
  • Lieutenant Governor’s Academic Medal, Dartmouth High School (2000).

Publications

*Equal contributions

  • Reddy, T., Li, X., Fliegel, L., Sykes, B.D., and Rainey, J.K. (2010) Correlating structure, dynamics, and function in transmembrane segment VII of the Na+/H+ exchanger isoform 1. Biochim Biophys Acta: Biomembranes. 1798: 94-104.  Pubmed
  • Reddy, T. and Rainey, J.K. (2010) Interpretation of biomolecular NMR spin relaxation parameters. Biochemistry and Cell Biology. 88: 131-142.  Pubmed
  • Langelaan, D.N., Bebbington, E.M., Reddy, T., and Rainey, J.K. (2009) Structural insight into G-protein coupled receptor binding by apelin. Biochemistry. 48: 537-548.  Pubmed
  • Reddy, T.*, Ding, J.*, Li, X., Sykes, B.D., Rainey, J.K., and Fliegel, L. (2008) Structural and Functional Characterization of Transmembrane Segment IX of the NHE1 Isoform of the Na+/H+ Exchanger. Journal of Biological Chemistry. 283: 22018-22030.  Pubmed  PDB entry (2K3C)  BMRB entry (15747)
  • Baguma-Nibasheka, M., Reddy, T., Abbas-Butt, A., and Kablar, B. (2006) Fetal ocular movements and retinal cell differentiation: analysis employing DNA microarrays. Histology and histopathology. 21: 1331-1337.  Pubmed
  • Reddy, T.*, Rot-Nikcevic, I.*, Downing, K.J., Belliveau, A.C., Hallgrímsson, B., Hall, B.K., and Kablar, B. (2006) Myf5-/-: MyoD-/- amyogenic fetuses reveal the importance of early contraction and static loading by striated muscle in mouse skeletogenesis. Development genes and evolution. 216: 1-9.  Pubmed
  • Reddy, T. and Kablar, B. (2004) Evidence for the involvement of neurotrophins in muscle transdifferentiation and acetylcholine receptor transformation in the esophagus of Myf5-/-:MyoD-/- and NT-3-/- embryos. Developmental Dynamics. 231: 683-692.  Pubmed

Conference Presentations and Invited Talks

Primary presenter underlined

  • Langelaan, D.N., Bebbington, E.M., Reddy, T., and Rainey, J.K. (2010) Evidence for membrane-catalyzed apelin-receptor binding. MOOT XXIII NMR Symposium, Dalhousie University, Halifax, N.S. (Poster)
  • Reddy, T., Sykes, B.D., and Rainey, J.K. (2010) Probing the effects of slow-exchange conformational sampling upon dynamics determined by peptide backbone 15N relaxation in a micellar environment. MOOT XXIII NMR Symposium, Dalhousie University, Halifax, N.S. (Poster)
  • Reddy, T., Hall, B., Chetwynd, A., and Sansom, M.S.P. (2010) Simulations of the Transmembrane Helix of the FGFR3 Receptor. Celebrating Computational Biology: A Tribute to Frank Blaney, St. Catherine's College, University of Oxford, Oxford, U.K. (Poster)
  • Reddy, T., Sykes, B.D., and Rainey, J.K. (2009) 15N backbone NMR relaxation studies of transmembrane segment VII of the Na+/H+ exchanger isoform 1. Nuclear Magnetic Resonance Research Resource (NMR3) 4th Annual Fall Workshop, Dalhousie University, Halifax, NS. (Poster)
  • Reddy, T., Sykes, B.D., and Rainey, J.K. (2009) Correlating Structure, Dynamics, and Function in Transmembrane Segment VII of the Na+/H+ Exchanger Isoform 1. 52nd Annual Meeting of the CSBMCB, Niagara-on-the-Lake, Ontario. (Poster)
  • Reddy, T., Sykes, B.D., and Rainey, J.K. (2009) 15N relaxation analysis of the Na+/H+ exchanger isoform 1 transmembrane segment VII. Graduate Student Research Day, Dalhousie University, Halifax, NS. (Poster)
  • Reddy, T., Sykes, B.D., and Rainey, J.K. (2009) Model-free analysis and reduced spectral density mapping of a micelle-solubilized peptide using 15N relaxation data. Chemical Biophysics Symposium, Toronto, ON. (Poster)
  • Reddy, T. (2009) Kinky Peptides: 15N Backbone NMR Relaxation Studies of a Na+/H+ Exchanger Isoform 1 Transmembrane Segment. Chemical Biology and Chemical Biophysics Networking Retreat, Halifax, NS. (Oral presentation)
  • Reddy, T. (2008) Structure and Dynamics of Na+/H+ Exchanger Isoform 1 (NHE1) Transmembrane Segments. 3rd Annual Atlantic Region Magnetic Resonance Centre NMR Spectroscopy Workshop, Halifax, NS. (Oral presentation)
  • Reddy, T. (2008) Structural study of the Na+/H+ exchanger isoform 1 (NHE1) transmembrane segment IX in micelles. Biochemistry 640--Biomembranes Discussion Group, University of Alberta, Edmonton, AB. (Invited talk)
  • Reddy, T., Ding, J., Li, X., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Correlating structure and function for transmembrane segment IX of the human Na+/H+ exchanger isoform 1. XXIIIrd International Conference on Magnetic Resonance in Biological Systems (ICMRBS), San Diego, CA. (Poster)
  • Rainey, J.K., Langelaan, D.N., and Reddy, T. (2008) Detecting and Dealing With Conformational Sampling in Peptides. XXIIIrd International Conference on Magnetic Resonance in Biological Systems (ICMRBS), San Diego, CA. (Poster)
  • Lemieux, M.J., Lamoureux, J., Mak, M., Fischer, S., Rainey, J.K., Reddy, T., and James, M. (2008) Structural and Functional Studies of the Rhomboid Intramembrane Peptidase from H. influenzae. The 22nd Annual Symposium of the Protein Society, San Diego, CA. (Poster)
  • Reddy, T., Ding, J., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Structural and Functional Characterization of Transmembrane Segment IX of the Na+/H+ Exchanger Isoform 1. Graduate Student Research Day, Dalhousie University, Halifax, NS. (Poster)
  • Langelaan, D.N., Bebbington, E.M., Reddy, T., and Rainey, J.K. (2008) NMR, circular dichroism & fluorescence spectroscopy provide insight into conformational sampling of apelin. Graduate Student Research Day, Dalhousie University, Halifax, NS. (Poster)
  • Reddy, T., Ding, J., Li, X., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Structure and topology of transmembrane segment IX of the human Na+/H+ exchanger isoform 1. 33rd Annual APICS/CIC Undergraduate Chemistry Conference, Halifax, NS. (Oral presentation)
  • Langelaan, D.N., Bebbington, E.M., Reddy, T., and Rainey, J.K. (2008) Structure in a Random Coil Peptide: The Apelin Story. 33rd Annual APICS/CIC Undergraduate Chemistry Conference, Halifax, NS. (Poster)
  • Reddy, T., Ding, J., Sykes, B.D., Fliegel, L., and Rainey, J.K. (2008) Structural and functional characterization of transmembrane segment IX of the Na+/H+ exchanger isoform 1. Chemical Biophysics Symposium, Toronto, ON. (Poster)
  • Langelaan, D.N., Bebbington, E.M., Reddy, T., and Rainey, J.K. (2008) NMR, circular dichroism & fluorescence spectroscopy provide insight into the random-coil nature of apelin peptides. Chemical Biophysics Symposium, Toronto, ON. (Poster)
  • Langelaan, D.N., Bebbington, E.M., Reddy, T., Grant, M., and Rainey, J.K. (2008) Conformational sampling by apelin peptides gives functional insight. Joint 52nd Annual Meeting of the Biophysical Society & 16th IUPAB International Biophysics Congress, Long Beach, CA. (Poster)
  • Reddy, T. and Rainey, J.K. (2007) NMR of transmembrane peptides. Atlantic Region Magnetic Resonance Centre NMR Spectroscopy Workshop, Halifax, NS. (Poster)
  • Kablar, B. and Reddy, T. (2004) The Role of Neurotrophins in the Esophageal Skeletal Muscle Transdifferentiation and Acetylcholine Receptor Transition. Society for Developmental Biology 63rd Annual Meeting, Calgary, AB. Developmental Biology. 271: 624. (Poster)


Upcoming Conference Presentations and Invited Talks

Primary presenter underlined

  • Reddy, T., Hall, B., Chetwynd, A., and Sansom, M.S.P. (2011) Molecular Dynamics Simulations of the Transmembrane Helix of the FGFR3 Receptor in POPC and DPPC. Biophysical Society 55th Annual Meeting, Baltimore Convention Centre, Baltimore, Maryland, U.S.A (Poster?)

Teaching Assistantships

  • Biochemistry for Pharmacy Students, Laboratory Instruction and Grading, Department of Biochemistry and Molecular Biology, Dalhousie University (2008).
  • Biochemistry for Nursing Students and Introductory Biochemistry, Assignment and Midterm Grading, Department of Biochemistry and Molecular Biology, Dalhousie University (2008).
  • Developmental Biology, Laboratory Instruction and Grading, Department of Biology, Dalhousie University (2005).
  • Developmental Biology, Laboratory Instruction and Grading, Department of Biology, Dalhousie University (2004).

Training Camps

  • Sun Microsystems Application Tuning Seminar, Halifax, Nova Scotia, Canada (2009).
  • Nuclear Magnetic Resonance (NMR) Boot Camp, The National High Field Nuclear Magnetic Resonance Centre (NANUC), Edmonton, Alberta, Canada (2007).
  • Canadian Forces Leadership and Recruit School, St-Jean-Sur-Richelieu, Quebec, Canada (2007).

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