User:Zach Bjornson: Difference between revisions
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[[Image:Zbb.jpg|right|thumb|Zach Bjørnson (©2006 Bart Nagel)]] | [[Image:Zbb.jpg|right|thumb|Zach Bjørnson (©2006 Bart Nagel)]] | ||
MIT | MIT Biology 2010 - S.B. | Stanford Microbiology and Immunology - graduate student (Ph.D. -- Nolan Lab) | ||
My primary | My primary focus is in Category A/BL4 pathogens (especially ebolavirus), and on the other end of the spectrum, I'm fascinated by rhinoviruses (major cause of the common cold). In both cases, I enjoy studying emerging pathogens and characterizing their differences from already-characterized bugs. I also enjoy studying the differences in immune responses between individuals with differing symptoms/outcomes after infection with the same virus. | ||
I | I have a side interest and some experience in mechanical and electrical engineering. | ||
You can contact me at bjornson{at} | You can contact me at bjornson{at}stanford{.}edu or bjornson{at}broadinstitute{.}org. | ||
== Current Research and | == Current Research and Biology Projects == | ||
*Long-term sequelae of ebolavirus infection in humans. (Nolan lab, with Hensley/Honko) | |||
*Immune profiling during fatal and nonfatal ebolavirus infection. (Nolan lab, with Hensley/Honko) | |||
*Identifying causal agents of fevers of unknown origin via Illumina sequencing. (Rubins lab and Sabeti lab) | |||
*20.109 research proposal assignment. ([http://openwetware.org/wiki/Enhancement_of_organogenesis_with_small_molecule_drugs wiki page]) | == Past Research and Biology Projects == | ||
*Assorted monkeypox transcriptomics and genomics; Ebola genomics. | |||
*Research proposal: Antigenic characterization of newly detected rhinovirus variants; vaccination via polyvalent recombinant capsid protein expression. (This is a detailed proposal about 20 pages in length. Two papers that came out in early 2009 support that this project would have produced generally favorable outcomes.) | |||
*Summer 2008: Developed a protocol to measure radical/reactive oxygen species in Gram-negative bacteria at the royal Chulabhorn Research Institute in Bangkok, Thailand. Also worked on isolating and identifying a compound (suspected to be homogentisic acid) from a Pseudomonas culture in which a certain oxidase was knocked out. | |||
*Optimization of Expression, Solubilization and Purification of the Membrane Protein HORF17-4 in E. coli Using Fractional Factorial Design (Zhang Lab) | *20.109 research proposal assignment: [enhancement of] vasculogenesis with statins and hyaluronan jelly. ''mock project only'' ([http://openwetware.org/wiki/Enhancement_of_organogenesis_with_small_molecule_drugs wiki page]) | ||
*Optimization of Expression, Solubilization and Purification of the Membrane Protein HORF17-4 in E. coli Using Fractional Factorial Design (Zhang Lab). | |||
*Optimization of Cell-Free Expression of Membrane Proteins with Self-Assembling Peptides (Zhang Lab) | *Optimization of Cell-Free Expression of Membrane Proteins with Self-Assembling Peptides (Zhang Lab) | ||
*Cloning and Expression of UGT1A1 in E. coli ([http://idp2.blogspot.com/ project blog]) | *Cloning and Expression of UGT1A1 in E. coli ([http://idp2.blogspot.com/ project blog]) | ||
*Airplane Drinking Water Testing for Microbial Contaminants | *Airplane Drinking Water Testing for Microbial Contaminants | ||
**[http://www.epa.gov/safewater/airlinewater/index2.html The EPA just proposed new regulations to enforce the cleanliness of drinking water served on airplanes!] | |||
**[http://yosemite.epa.gov/opa/admpress.nsf/2dd7f669225439b78525735900400c31/11514a2d88923596852570d8005e1734!OpenDocument U.S. EPA honors 37 environmental heroes at Earth Day ceremony] | **[http://yosemite.epa.gov/opa/admpress.nsf/2dd7f669225439b78525735900400c31/11514a2d88923596852570d8005e1734!OpenDocument U.S. EPA honors 37 environmental heroes at Earth Day ceremony] | ||
**[http://online.wsj.com/public/article_print/SB1036110025940498271.html How Safe Is Airline Water? Bring Your Own Bottle!] | **[http://online.wsj.com/public/article_print/SB1036110025940498271.html How Safe Is Airline Water? Bring Your Own Bottle!] | ||
| Line 25: | Line 30: | ||
**As well as others | **As well as others | ||
== Honors == | == Honors and Media == | ||
*2010 William L. Stewart MIT Institute Award | |||
*2010 Jeff Roberts Award | |||
*2010 William and Betsy Leitch Award | |||
*Special Congressional Recognition for Environmental Work | *Special Congressional Recognition for Environmental Work | ||
*Environmental Protection Agency environmental service award | *Environmental Protection Agency environmental service award | ||
| Line 31: | Line 39: | ||
*2005 International Young Eco-Hero Award | *2005 International Young Eco-Hero Award | ||
*June 22, 2006 designated in Moraga, CA as a day of recognition | *June 22, 2006 designated in Moraga, CA as a day of recognition | ||
*''Ready, set, go: Class of 2010 leaps into action.'' [http://web.mit.edu/newsoffice/2006/freshmen-0913.html MIT Tech Talk article.] | |||
*''A Genius for Leadership: MIT's Amazing Students.'' [http://spectrum.mit.edu/issue/2007-summer/a-genius-for-leadership/ MIT Spectrum Summer 2007 article.] (Cover page and following pages.) | |||
*''Making their own music.'' [http://web.mit.edu/newsoffice/2007/music-instruments-tt1212.html MIT Tech Talk article.] | |||
*See also the links above, in ''projects.'' | |||
== Lab Skills and Areas of Experience == | |||
*Molecular diagnostics (advanced design and applications of real-time PCR, etc.) | |||
*Flow cytometry, mass cytometry (panel design, advanced analysis) | |||
*Sequencing (Sanger, Illumina, 454, principally of viruses; including analysis) | |||
*Microarrays (design, processing, analysis) | |||
*Bioinformatics (as noted throughout; high-performance computing, software design; Mathematica, C++, R, Java, C#, VB, others) | |||
*Process optimization (D-optimal and fractional factorial design of experiments; process scale-up) | |||
*Cell culture (2D and 3D; most types of bioreactors for mammalian cell and virus growth) | |||
*General molecular biology (protein gels, Westerns, FPLC, HPLC, Northerns, cloning, SDM) | |||
*Various mechanical engineering skills, including systems automation, robotics and fluids handling. | |||
== Other Interests == | == Other Interests == | ||
I play | I play organ. | ||
I'm from the San Francisco Bay Area. I'm a vegetarian, tree-hugger, environmentalist, | I'm from the San Francisco Bay Area. I'm a vegetarian, tree-hugger, environmentalist, ... spreading San Francisco values. | ||
And I love to travel. | |||
== Personal Sites == | == Personal Sites == | ||
*[http://hemsch.blogspot.com Harpsichord Project Blog] | *[http://hemsch.blogspot.com Harpsichord Project Blog] | ||
*[http://utopia. | *[http://utopia.stanford.edu My main portal site] (previously utopia.mit.edu) | ||
Latest revision as of 13:41, 28 February 2012
MIT Biology 2010 - S.B. | Stanford Microbiology and Immunology - graduate student (Ph.D. -- Nolan Lab)
My primary focus is in Category A/BL4 pathogens (especially ebolavirus), and on the other end of the spectrum, I'm fascinated by rhinoviruses (major cause of the common cold). In both cases, I enjoy studying emerging pathogens and characterizing their differences from already-characterized bugs. I also enjoy studying the differences in immune responses between individuals with differing symptoms/outcomes after infection with the same virus.
I have a side interest and some experience in mechanical and electrical engineering.
You can contact me at bjornson{at}stanford{.}edu or bjornson{at}broadinstitute{.}org.
Current Research and Biology Projects
- Long-term sequelae of ebolavirus infection in humans. (Nolan lab, with Hensley/Honko)
- Immune profiling during fatal and nonfatal ebolavirus infection. (Nolan lab, with Hensley/Honko)
- Identifying causal agents of fevers of unknown origin via Illumina sequencing. (Rubins lab and Sabeti lab)
Past Research and Biology Projects
- Assorted monkeypox transcriptomics and genomics; Ebola genomics.
- Research proposal: Antigenic characterization of newly detected rhinovirus variants; vaccination via polyvalent recombinant capsid protein expression. (This is a detailed proposal about 20 pages in length. Two papers that came out in early 2009 support that this project would have produced generally favorable outcomes.)
- Summer 2008: Developed a protocol to measure radical/reactive oxygen species in Gram-negative bacteria at the royal Chulabhorn Research Institute in Bangkok, Thailand. Also worked on isolating and identifying a compound (suspected to be homogentisic acid) from a Pseudomonas culture in which a certain oxidase was knocked out.
- 20.109 research proposal assignment: [enhancement of] vasculogenesis with statins and hyaluronan jelly. mock project only (wiki page)
- Optimization of Expression, Solubilization and Purification of the Membrane Protein HORF17-4 in E. coli Using Fractional Factorial Design (Zhang Lab).
- Optimization of Cell-Free Expression of Membrane Proteins with Self-Assembling Peptides (Zhang Lab)
- Cloning and Expression of UGT1A1 in E. coli (project blog)
- Airplane Drinking Water Testing for Microbial Contaminants
Honors and Media
- 2010 William L. Stewart MIT Institute Award
- 2010 Jeff Roberts Award
- 2010 William and Betsy Leitch Award
- Special Congressional Recognition for Environmental Work
- Environmental Protection Agency environmental service award
- United Nations Environment Programme youth advisor
- 2005 International Young Eco-Hero Award
- June 22, 2006 designated in Moraga, CA as a day of recognition
- Ready, set, go: Class of 2010 leaps into action. MIT Tech Talk article.
- A Genius for Leadership: MIT's Amazing Students. MIT Spectrum Summer 2007 article. (Cover page and following pages.)
- Making their own music. MIT Tech Talk article.
- See also the links above, in projects.
Lab Skills and Areas of Experience
- Molecular diagnostics (advanced design and applications of real-time PCR, etc.)
- Flow cytometry, mass cytometry (panel design, advanced analysis)
- Sequencing (Sanger, Illumina, 454, principally of viruses; including analysis)
- Microarrays (design, processing, analysis)
- Bioinformatics (as noted throughout; high-performance computing, software design; Mathematica, C++, R, Java, C#, VB, others)
- Process optimization (D-optimal and fractional factorial design of experiments; process scale-up)
- Cell culture (2D and 3D; most types of bioreactors for mammalian cell and virus growth)
- General molecular biology (protein gels, Westerns, FPLC, HPLC, Northerns, cloning, SDM)
- Various mechanical engineering skills, including systems automation, robotics and fluids handling.
Other Interests
I play organ.
I'm from the San Francisco Bay Area. I'm a vegetarian, tree-hugger, environmentalist, ... spreading San Francisco values.
And I love to travel.
Personal Sites
- Harpsichord Project Blog
- My main portal site (previously utopia.mit.edu)
