User talk:Kam D. Dahlquist: Difference between revisions

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Hey Dr. Dahlquist!! Why did you choose to co-teach a math class instead of merely staying in the field of biology? [[User:Sarah Carratt|Sarah Carratt]] 16:56, 16 January 2011 (EST)
*What methods do you use in researching "The Global Transcriptional Response of Saccharomyces cerevisiae to Cold Shock and Recovery"? [[User:Lauren M. Kelly|Lauren M. Kelly]] 16:13, 15 January 2017 (EST)
 
** We use a technology called DNA microarrays that can measure the expression of all the genes in yeast at once. We will be learning about this in the second half of the semester.  ''— [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 19:53, 18 January 2017 (EST)''
Hello there Dr. Dahlquist! After reading Janovy, I was wondering if you can recall your earliest memory that might have lead you to the career path you have chosen?
*Will the Bioremediation processes being studied on the Ballona Wetlands be affective in different soil types across the world?*'''[[User:Cameron M. Rehmani Seraji|Cameron M. Rehmani Seraji]] 23:55, 16 January 2017 (EST)''':
[[User:Carmen E. Castaneda|Carmen E. Castaneda]] 08:36, 16 January 2011 (EST)
** That's not really my area of expertiseMy project in the wetlands was sampling soil bacteria and identifying them by their 16S rRNA sequence tagsIf phytoremediation is used, i.e., plants are grown to suck up the contaminants and then harvested to discard, it would work as long as the plant could grow thereDr. Drennan is more of an expert on this than me.  ''— [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 19:56, 18 January 2017 (EST)''
 
*What influenced you to embrace the mathematical side of biology? Was it a specific person? Research you came across?  [[User:Conor Keith|Conor Keith]] 00:07, 18 January 2017 (EST)
Hi Dr. Dahlquist! I was wondering why you chose to study cell biology other than any other discipline in the Biology field?[[User:Alondra Vega|Alondra Vega]] 11:57, 16 January 2011 (EST)
** I started when I was a postdoc and realized that statistics were required to analyze the microarray data that I was working withI started the modeling project when I came to LMU because I wanted to understand the gene regulatory networks I was studying at a deeper levelSo I really got interested in math to use as a tool to answer the biological questions I had.  ''— [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 20:01, 18 January 2017 (EST)''
 
*What prompted you and Dondi to create the XMLPipeDB and what sparked your interest in expanding the amount of open source software available? [[User:Margaret J. Oneil|Margaret J. Oneil]] 00:22, 19 January 2017 (EST)
Hello Dr. Dahlquist. Perhaps a simple question for you: What do you think is the role of engineering in the field of bio research?
** We started XMLPipeDB to solve a problem that GenMAPP was having, i.e., it was difficult to update or create new Gene Databases so that it could be used to analyze those species' dataAt the time we started, the computer science professors had an NSF grant to bring open source development into their undergraduate curriculum and I had been frustrated as a postdoc because GenMAPP did not start out as being open sourceWhen Dr. Dionisio explained to me the other facets of open source culture, besides the license, I was in.  The rest, as they say, is history.  ''‐ [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 02:17, 24 January 2017 (EST)''
[[User:James C. Clements|James C. Clements]] 00:30, 17 January 2011 (EST)
*Prior to starting the modeling project at LMU had you ever been introduced to a similar project during your education that helped shape the current project? *'''[[User:Nika Vafadari|Nika Vafadari]] 02:34, 19 January 2017 (EST)''':
 
** During my postdoc, I had previously worked on analyzing DNA microarray data by visualizing the data on pathways, but it didn't involve modeling, just statistics, and we were not studying gene regulatory pathways, mainly metabolic pathwaysMy interest in systems biology and gene regulatory networks was inspired, in part, by reading books on my own, especially those by Stuart Kauffman of the Santa Fe Institute (a research institute for complex systems).  I attended a talk he gave at UC Santa Cruz, which must have been 20 years ago now.  ''— [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 02:44, 24 January 2017 (EST)''
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Dr. Dahlquist, I would like to know the work ethic that it takes to become a prominent scientist or member to the scientific community? [[User:Bobak Seddighzadeh|Bobak Seddighzadeh]] 03:20, 26 January 2010 (EST)Bobak Seddighzadeh
 
: Bobak, scientists work very hard with long hours.  One of the difficult things about being a scientist is finding a balance between work and a personal life.  ''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 21:53, 27 January 2010 (EST)''  
 
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Hey Dr. Dahlquist, I was wondering what made you decide to become a professor in Biology?
--[[User:Kristoffer T. Chin|Kristoffer T. Chin]] 15:48, 20 January 2010 (EST)
 
Hi Dr. Dahlquist! I was wondering how you decided to become a professor and what drew you to come work at LMU? [[User:Amanda N. Wavrin|Amanda N. Wavrin]] 21:12, 23 January 2010 (EST)
 
: Kris and Amanda, your questions are related, so I'll answer them together.  I have always loved school since I was a little kid, and I always admired my teachers.  So, I wanted to be a teacher since I was a little kid.  Each year I advanced in school, I wanted to teach that grade, so by the time I got to college, I wanted to be a college professor.  I went to college at Pomona College, which is a liberal arts college smaller than LMU.  I really liked that environment because I'm not just interested in biology, but in other fields such as philosophy, ethics, politics, the arts, etc.  I thought that if I could teach at a liberal arts college, I would have more opportunities to interact with colleagues in those fields in addition to teaching and doing research in biology, which I love.
 
: Finding a faculty position involves an element of luckThe colleges and universities that have positions open in your field at the time you are ready to look for a job is a little random.  I was lucky there was a position open for someone in my field when I was looking.  When I interviewed at LMU, I was impressed by the collegiality and community shown by the faculty and students.  I liked how faculty were collaborative in their teaching and researchI enjoyed the time I spent having pizza with the biology students in particular.  I'm very glad that I made the decision to come here.  ''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 22:03, 27 January 2010 (EST)''
 
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Hi Dr. Dahlquist, My question is how did you become so good at using computers and websites such as this? [[User:J&#39;aime C. Moehlman|J&#39;aime C. Moehlman]] 19:17, 20 January 2010 (EST)
 
: J'aime, in a word, practice, practice, practice.  I am motivated to learn new things because it helps me with my research and teaching.  I'm willing to try new things even though it can be uncomfortable at first, especially when I am first learningI am not afraid of making a mistake or breaking the computer. I try to work with people who know more than me and I pay attention to what they do and try it myself.  I first learned how to use MediaWiki about two years ago. Mostly, I just looked at other people's code and used trial and error to figure out how to do stuff.  Because I have so much experience now, even with something new, I generally know how to figure things out.  As you gain experience, you will be able to learn things faster.  So, be willing to learn and don't be afraid to try something new! ''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 22:08, 27 January 2010 (EST)''
 
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What's up, Dr. Dahlquist? (I had to use a different greeting than the two before me)  Anyway, if you could choose one place in the world to live for a year, where would it be and why--[[User:Alex J. George|Alex J. George]] 00:17, 21 January 2010 (EST)
 
: Alex, hmmmm.  My favorite place that I lived in the past was Santa Cruz, where I went to graduate school.  I was sad to leave there after living there for four years.  It was a beautiful place to live, next to the beach and mountainsAlso, it had a lot of book stores, good restaurants, and whole food stores (the real kind that sells grains in bins, not the Whole Foods chain).  Two years ago, my husband and I traveled in Austria because I went to a conference held in Vienna.  I thought that Vienna would be a great European city to live in--great art, great music, great public transportation, great coffee and chocolate, but what we really liked was the lake district around Salzburg.  It seemed like it would just be a very beautiful place to live''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 22:15, 27 January 2010 (EST)''
 
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Good Afternoon Dr. Dahlquist, My question is if you were given the opportuinty to switch careers would you do so? And if you would what would it be and why? *'''[[User:Salomon Garcia Valencia|Salomon Garcia Valencia]] 18:27, 23 January 2010 (EST)''':
 
: Salomon, It's hard for me to imagine a life in which I wasn't doing science.  All the things I could imaging switching to still involve science somehow.  I'm becoming more and more interested in politics and government.  AAAS offers fellowships for scientists to be advisors to the federal government for a year (either working for Congress or the Executive branch) and I might apply to do that sometime.  I'm also interested in investigative journalism, which is going away now that newspapers are dying.  My favorite non-science job I've ever had is working at an independent book store (although those are going away, too).  ''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 22:20, 27 January 2010 (EST)''
 
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Dr. Dahlquist, what is your philosophy of teaching? How has this philosophy changed (if it has) over the course of your career? [[User:Janelle N. Ruiz|Janelle N. Ruiz]] 03:12, 24 January 2010 (EST)
 
: Janelle, when you apply for a faculty position, you have to write a teaching philosophy.  I add to this statement every year as part of my faculty service report (a yearly report on my teaching/advising, research, and service that I submit to the Chair of the department and Dean), and I updated it quite substantially as part of my application for tenure and promotion to Associate Professor last year.  The take-home message of my teaching philosophy is that science is a process and you learn it by doing it.  When I design a course, I reflect upon what I do as a practicing scientist and how break that down into manageable steps that students can take.  I reflect on what I know (with my head), what skills I have (with my hands), and the personal qualities that I need (with my heart) to do my science.  I try to include authentic research into my courses.  I would say that my philosophy has matured over time so that I have become more student-centered instead of teacher-centered.  I have gained a lot of practical experience that I did not have at the beginning on how to manage the logistics of a course.  I participate in the scholarship of teaching and learning which is a scientific way to approach teaching where I gather data on what and how students learn and use that information to improve my teaching the next time.  This course is very much in keeping with the philosophy that you learn by doing.  ''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 22:37, 27 January 2010 (EST)''
 
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Hello Dr. Dahlquist, I wanted to ask if you hope to center on teach Bioinformatics full time at Loyola if you had a choice. I know that you were a great professor for Cell Function, but i feel as we got into Bioinformatics things got even better and seemed to be a very strong fit. Again, this would be only if it was your choice to fully teach Bioinformatics, or do you prefer teaching both?
[[User:Kevin A Paiz-Ramirez|Kevin A Paiz-Ramirez]] 9:15 pm, 24 jan 2010 (EST)
: Kevin, I like teaching courses at all levels of the curriculum, both lower division, like Cell Function, and upper division, like Biological Databases, Bioinformatics Lab, and Molecular Biology of the Genome.  I also like to teach courses for non-science majors (even though I only got to do that once) and seminars for seniors (I've only done that once as well)The one thing that I would like to do with Cell Function is to have the opportunity to take students into the computer lab to do some bioinformatics.  There is a lot we could do that would fit with the course, but because of the class size, there's no computer lab I can use.  I would like it even better if we could actually have a lab section for the course so that we could do some lab experiments that went along with the content of the course.  I really like teaching courses where there is some type of lab or practical aspect where we get down to doing real research.  ''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 22:44, 27 January 2010 (EST)''
 
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Hi Dr. Dahlquist, I was wondering what was your first course that made you so interested in Bioinformatics?  Also, what were your strategies in developing your skills?  00:26, 25 January 2010 (EST) [[ User:Ryan N. Willhite|Ryan N. Willhite]]
 
: Ryan, I never took a course in bioinformatics (at least in the way that you probably mean) because those courses did not exist when I was in college or graduate schoolI started teaching bioinformatics workshops myself when I was a postdoctoral researcher. I got interested in the field because I was interested in how biological pathways worked in a cell.  But when I was in graduate school, people would take two years to clone and sequence a single gene, let alone all the genes in a pathway.  When the human genome project was completed, we finally had the technology to study all the genes at once and I was excited that we could start answering the questions I had about pathways in the cellTo make the best use of this technology, we needed computer programs to analyze the data, so bioinformatics was a good fit for me.  ''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 22:57, 27 January 2010 (EST)''
 
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Hello, Dr. D. What are you favorite and least favorite aspects of having a career in academia? '''[[User:Angela A. Garibaldi|Angela A. Garibaldi]] 23:47, 25 January 2010 (EST)''':
 
: Angela, my favorite aspect of working in academia is that I get paid to do what I love--learn new things.  My least favorite aspect is that academia is essentially a feudal system that has not changed much since the 1600's when it was invented.  It is set up so that the people at the bottom have very little power and the people at the top have a lot of power, with lots of step functions where the result is all or none (getting your PhD, getting tenure).  Also, there are still very few women at the top (full professors, administrators).  There is a lot of sexism and misogyny that go on that would not be tolerated in other sectors of society.  But still, I think this is the best career for me''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 23:05, 27 January 2010 (EST)''
 
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Besides the areas of your research (including Bioinformatics, ribosome structure, yeast, etc.) what other aspects of Biology interest you the most? [[User:Michael R. Pina|Michael R. Pina]] 11:19, 26 January 2010 (EST)
 
: Michael, that's a tough question, you've named all of my favorite areas of biology! :) I like learning about evolution because it is the foundation of biology.  I subscribe to both ''Science'' and ''Nature'' and I like to browse the articles to keep abreast of what's current in general in biology, so in some sense, I could say that I like it all.  Things that draw my attention tend to be "big picture" questions that look at things like a system.  That's why biology is so exciting right now because more and more researchers are asking system's level questions.  ''&mdash; [[User:Kam D. Dahlquist|Kam D. Dahlquist]] 23:08, 27 January 2010 (EST)''
 
== Week 4 assignment ==
 
Hi Dr. Dahlquist, I have a question on the assignment for this week.  I am currently having a difficult time understanding Part 2 Activity 2 in calculating for Min and Max Difference.  In the first table, I was able to use the Clustdist tool with one of my alignments with 3 clones.  The page that it took me gave me a screen that looks like this
[[Image:Untitled.JPG|Center|1000px]]
 
The problem I have is now calculating for the min difference and the max difference. I am not sure how i am supposed to select the highest and lowest pairwise scores.  Do it add up all the distance matrix for the x-coordinate of S2V1-3 and then compare that to the other clones and use the smallest sum and highest sum and those would be my min and max difference after multiplication of 285?
 
I am also having a difficult time understanding how to look at the maximum and minimum difference across subjects.  The instructions are a bit unclear
--[[User:Kristoffer T. Chin|Kristoffer T. Chin]] 00:19, 13 February 2010 (EST)
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Revision as of 00:44, 24 January 2017

  • What methods do you use in researching "The Global Transcriptional Response of Saccharomyces cerevisiae to Cold Shock and Recovery"? Lauren M. Kelly 16:13, 15 January 2017 (EST)
    • We use a technology called DNA microarrays that can measure the expression of all the genes in yeast at once. We will be learning about this in the second half of the semester. Kam D. Dahlquist 19:53, 18 January 2017 (EST)
  • Will the Bioremediation processes being studied on the Ballona Wetlands be affective in different soil types across the world?*Cameron M. Rehmani Seraji 23:55, 16 January 2017 (EST):
    • That's not really my area of expertise. My project in the wetlands was sampling soil bacteria and identifying them by their 16S rRNA sequence tags. If phytoremediation is used, i.e., plants are grown to suck up the contaminants and then harvested to discard, it would work as long as the plant could grow there. Dr. Drennan is more of an expert on this than me. Kam D. Dahlquist 19:56, 18 January 2017 (EST)
  • What influenced you to embrace the mathematical side of biology? Was it a specific person? Research you came across? Conor Keith 00:07, 18 January 2017 (EST)
    • I started when I was a postdoc and realized that statistics were required to analyze the microarray data that I was working with. I started the modeling project when I came to LMU because I wanted to understand the gene regulatory networks I was studying at a deeper level. So I really got interested in math to use as a tool to answer the biological questions I had. Kam D. Dahlquist 20:01, 18 January 2017 (EST)
  • What prompted you and Dondi to create the XMLPipeDB and what sparked your interest in expanding the amount of open source software available? Margaret J. Oneil 00:22, 19 January 2017 (EST)
    • We started XMLPipeDB to solve a problem that GenMAPP was having, i.e., it was difficult to update or create new Gene Databases so that it could be used to analyze those species' data. At the time we started, the computer science professors had an NSF grant to bring open source development into their undergraduate curriculum and I had been frustrated as a postdoc because GenMAPP did not start out as being open source. When Dr. Dionisio explained to me the other facets of open source culture, besides the license, I was in. The rest, as they say, is history. Kam D. Dahlquist 02:17, 24 January 2017 (EST)
  • Prior to starting the modeling project at LMU had you ever been introduced to a similar project during your education that helped shape the current project? *Nika Vafadari 02:34, 19 January 2017 (EST):
    • During my postdoc, I had previously worked on analyzing DNA microarray data by visualizing the data on pathways, but it didn't involve modeling, just statistics, and we were not studying gene regulatory pathways, mainly metabolic pathways. My interest in systems biology and gene regulatory networks was inspired, in part, by reading books on my own, especially those by Stuart Kauffman of the Santa Fe Institute (a research institute for complex systems). I attended a talk he gave at UC Santa Cruz, which must have been 20 years ago now. Kam D. Dahlquist 02:44, 24 January 2017 (EST)