VCU/Courses/Synthetic Biology Fundamentals: Difference between revisions

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==Course Overview==
==Course Overview==
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This course aims to provide an introduction to synthetic biology for motivated undergraduate students at Virginia Commonwealth University.  The main goal of this course is to introduce the engineering principles and tools necessary to design, model and build a functional biological system and, in doing so, program novel cellular function and behavior to solve engineering problems and test biological hypotheses.
This seminar course aims to introduce foundational concepts in synthetic biology and survey current synthetic biology research.
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Synthetic biology is emerging as a new engineering discipline, applying engineering principles such as the standardization of modular components, the hierarchical abstraction of complex systems, and the characterization of both components and systems to biology, allowing the decoupling of construction from design.  Novel biological systems may be engineered to solve industrial, medical and environmental engineering problems such as the bioremediation of toxic waste, the microbial production of the anti-malarial drug artemisinin, and the biosynthesis of hydrogen or butanol as an alternative fuel source.
Synthetic biology is emerging as a rational, universal framework for designing and constructing biological systems by applying engineering principles such as standardization (e.g., of modular components) and abstraction (e.g., of complex systems) to biology with the aim of designing new biological components/systems or re-designing natural biological components/systems for novel purposes.  This concept of synthetic biology is not a new one, but has recently been enabled by de novo DNA synthesis technology, the streamlined practice of recombinant DNA technology (i.e., genetic "engineering") and the knowledge generated by both molecular and systems biology.  Novel biological systems may be engineered to solve industrial, medical and environmental engineering problems such as the biosensing and bioremediation of toxins, the microbial production of vaccines and drugs, and the biosynthesis of future transportation fuels.  
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Course instructor: George McArthur <br />
Faculty instructor: Dr. Stephen Fong <br />
Faculty administrator: Dr. Stephen Fong <br />
Graduate instructor: [[User:GMcArthurIV| George McArthur]] <br />
Meeting times: TBA <br />
Meeting times: MW 3-4:14 <br />
Questions?  Contact [mailto:mcarthurgh@vcu.edu George McArthur]
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==Expectations==
==Background==
 
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*[http://www.nature.com/nature/comics/syntheticbiologycomic/index.html Synthetic biology comic]
*[http://www.wired.com/culture/geekipedia/magazine/geekipedia/synthetic_biology Brief definition of synthetic biology]
*[http://www.newsweek.com/id/34406/page/1 ''Life 2.0'' Newsweek article]
*[http://weisswebserver.ee.princeton.edu/papers/SciAm_BioFab_2006_06.pdf Scientific American's ''Engineering Life: Building a FAB for Biology]
*[http://www.etcgroup.org/upload/publication/pdf_file/602 ETC Group's ''Introduction to Synthetic Biology'' manifesto]
*[http://www.youtube.com/watch?v=XIuh7KDRzLk Drew Endy defining synthetic biology (video)]
==News==
==News==
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*Under construction!
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==Recent Updates==
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Latest revision as of 11:36, 2 September 2009

Synthetic Biology Fundamentals

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Course Overview


This seminar course aims to introduce foundational concepts in synthetic biology and survey current synthetic biology research.

Synthetic biology is emerging as a rational, universal framework for designing and constructing biological systems by applying engineering principles such as standardization (e.g., of modular components) and abstraction (e.g., of complex systems) to biology with the aim of designing new biological components/systems or re-designing natural biological components/systems for novel purposes. This concept of synthetic biology is not a new one, but has recently been enabled by de novo DNA synthesis technology, the streamlined practice of recombinant DNA technology (i.e., genetic "engineering") and the knowledge generated by both molecular and systems biology. Novel biological systems may be engineered to solve industrial, medical and environmental engineering problems such as the biosensing and bioremediation of toxins, the microbial production of vaccines and drugs, and the biosynthesis of future transportation fuels.

Faculty instructor: Dr. Stephen Fong
Graduate instructor: George McArthur
Meeting times: MW 3-4:14

Background

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News