Department of Anesthesiology, University of Tübingen
Department of Anesthesiology, Klinikum rechts der Isar, Munich
Department of Anesthesiology, Brüderkrankenhaus Trier
Research Associate in Anesthesiology, University of Virginia
Research Interests: Voltage-gated Ca2+ channels (T-type), anesthetic effects on molecular targets in neuronal networks,
Methods: Current clamp recordings in cell-attached and whole-cell mode, voltage clamp recordings, inside-out-configuration, spinal cultured neurons, brain slice technique
Patent: Intrajugular balloon catheter for prevention of air embolism" (DE102011106676.8)
Selected Publications: Eckle VS, Grasshoff C. Intrajugular balloon catheter for prevention of air embolism. J Neurosurg Anesthesiol. 2011 Nov 29. [Epub ahead of print] Choe W, Messinger RB, Leach E, Eckle VS, Obradovic A, Salajegheh R, Jevtovic-Todorovic V, Todorovic SM. TTA-P2 is a potent and selective blocker of T-type calcium channels in rat sensory neurons and a novel antinociceptive agent. Mol Pharmacol. 2011;80:900-10. Eckle VS, Todorovic SM. Mechanisms of inhibition of CaV3.1 T-type calcium current by aliphatic alcohols. Neuropharmacology. 2010;59:58-69. Haseneder R, Kratzer S, Kochs E, Eckle VS, Zieglgänsberger W, Rammes G. Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala. Anesthesiology. 2008;109:998-1006. Eckle VS, Buchmann A, Bursch W, Schulte-Hermann R, Schwarz M. Immunohistochemical detection of activated caspases in apoptotic hepatocytes in rat liver. Toxicol Pathol. 2004;32:9-15.