Veit-Simon Eckle
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Lebenslauf
| Dr. Veit-Simon Eckle Waldhörnlestr. 22 | ||
| Residency: | Department of Anesthesiology, University of Tübingen Department of Anesthesiology, Klinikum rechts der Isar, Munich | |
| Fellowship: | Research Associate, Department of Anesthesiology (Prof. SM. Todorovic, Todorovic Lab) and Pharmacology (Prof. E. Perez Reyes Perez-Reyes Lab), University of Virginia, Charlottesville, Virginia, USA | |
| Research Interests: | Anesthetic effects on molecular targets in neuronal networks, GABAA and glycine receptors, voltage-gated Ca2+ channels (T-type), two-pore-potassium channels (TREK), spinal cord | |
| Methods: | Current clamp recordings in cell-attached and whole-cell mode, voltage clamp recordings, inside-out-configuration, cultured spinal neurons, brain slice technique | |
| Awards: | 3rd Prize, oral presentation competition: "Propofol modulates rather phasic than tonic GABAergic currents in the spinal ventral horn", 14th Capital City Conference of the DGAI, Congress of Anesthesiology and Intensive Care Medicine, September 2012 WAKWIN Mentee, German Society for Anaesthesiology and Intensive Care, 2010 | |
| Patent: | Intrajugular balloon catheter for prevention of air embolism (DE102011106676.8) | |
| Professional Societies: | German Society for Anaesthesiology and Intensive Care European Society of Anaesthesiology |
Selected Publications:
- Eckle VS, Digruccio MR, Uebele VN, Renger JJ, Todorovic SM. Inhibition of T-type calcium current in rat thalamocortical neurons by isoflurane. Neuropharmacology. 2012 Aug;63(2):266-73 PubMed
- Eckle VS, Grasshoff C. Intrajugular balloon catheter for prevention of air embolism. J Neurosurg Anesthesiol. 2012 Jan;24(1):81-2. PubMed
- Choe W, Messinger RB, Leach E, Eckle VS, Obradovic A, Salajegheh R, Jevtovic-Todorovic V, Todorovic SM. TTA-P2 is a potent and selective blocker of T-type calcium channels in rat sensory neurons and a novel antinociceptive agent. Mol Pharmacol. 2011;80:900-10. PubMed
- Eckle VS, Todorovic SM. Mechanisms of inhibition of CaV3.1 T-type calcium current by aliphatic alcohols. Neuropharmacology. 2010;59:58-69. PubMed
- Eckle VS, Hucklenbruch C, Todorovic SM. What do we know about anesthetic mechanisms?: hypnosis, unresponsiveness to surgical incision and amnesia. Anaesthesist. 2009 Nov;58(11):1144-9. PubMed
- Haseneder R, Kratzer S, Kochs E, Eckle VS, Zieglgänsberger W, Rammes G. Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala. Anesthesiology. 2008;109:998-1006. PubMed
- Eckle VS, Buchmann A, Bursch W, Schulte-Hermann R, Schwarz M. Immunohistochemical detection of activated caspases in apoptotic hepatocytes in rat liver. Toxicol Pathol. 2004;32:9-15. PubMed



