Vijaya Parthiban - Revision history

Parthi: /* Institutions */

2010-08-10T11:37:34Z

Institutions

←Older revision		Revision as of 11:37, 10 August 2010
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	==Institutions==		==Institutions==

-	In the '''Sanger Institute''', I am ~~currently associated with~~ the Genome dynamics and Evolution group, and ~~working~~ on genomics of rare diseases.	+	In the '''Sanger Institute''', I am in the Genome dynamics and Evolution group, and my work is on genomics of rare diseases. Currently, I am using exome resequencing data to detect CNVs across multiple individuals.

-	I ~~had also been~~ associated with several proteomics projects (stem cell biology, pathogen ~~proteomics~~, etc.) and ~~develop~~ computational tools for systems biology and mass spectrometry.	+	Previously, I was in the proteomic mass spectrometry group. I was associated with several proteomics projects (stem cell biology, pathogen biology, etc.) and developed computational tools for systems biology and mass spectrometry.

-	I did my PhD in '''Cologne University Bioinformatics Centre (CUBIC)''', one of the highly funded bioinformatics facilities in the world and the quality of research there is exceptional in its class. Besides, I ~~have also been~~ selected for the international Ph.D. program offered by [http://www.mpiz-koeln.mpg.de/english/studentInformation/IMPRScologne/index.html International Max Planck Research School] (IMPRS) ~~which involves competitive selection strategies~~. The scientific, social and career oriented training ~~offered by this program helps the students to compete~~ in ~~international level~~.	+	I did my PhD in '''Cologne University Bioinformatics Centre (CUBIC)''', one of the highly funded bioinformatics facilities in the world and the quality of research there is exceptional in its class. Besides, I was selected for the international Ph.D. program offered by [http://www.mpiz-koeln.mpg.de/english/studentInformation/IMPRScologne/index.html International Max Planck Research School] (IMPRS). The scientific, social and career oriented research and training in IMPRS was phenomenal for my research career in bioinformatics.

	==Research==		==Research==

Parthi: /* Vijaya Parthiban's Page in OpeWetWare */

2010-03-29T09:21:07Z

Vijaya Parthiban's Page in OpeWetWare

←Older revision		Revision as of 09:21, 29 March 2010
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-	=Vijaya Parthiban's Page in ~~OpeWetWare~~=	+	=Vijaya Parthiban's Page in OpenWetWare=

-	I am a post doctoral computational biologist in the [http://www.sanger.ac.uk/ Wellcome Trust Sanger Institute] in Cambridge (UK). I did my Ph.D. and worked as a 'staff scientist' in [http://www.cubic.uni-koeln.de Colonge University Bioinformatics Center, Germany] before moving to Cambridge. I was selected for the Ph.D. program in the International Max Planck Research School in Cologne in 2002.	+	I am a post doctoral computational biologist in the [http://www.sanger.ac.uk/ Wellcome Trust Sanger Institute] in Cambridge (UK). I did my Ph.D. and worked as a 'staff scientist' in [http://www.cubic.uni-koeln.de Colonge University Bioinformatics Center, Germany] before moving to Cambridge. I was selected for the Ph.D. program in the International Max Planck Research School in Cologne in 2002. '''[http://www.parthi.net http://www.parthi.net]''' redirects to this page for the time being! I am moving to a new hosting provider soon.
-	'''~~More details are available from my personal website:~~ [http://www.parthi.net http://www.parthi.net]'''	+

	==Institutions==		==Institutions==
-

	In the '''Sanger Institute''', I am currently associated with the Genome dynamics and Evolution group, and working on genomics of rare diseases.		In the '''Sanger Institute''', I am currently associated with the Genome dynamics and Evolution group, and working on genomics of rare diseases.

Parthi: /* Institutions */

2010-03-19T12:05:54Z

Institutions

←Older revision		Revision as of 12:05, 19 March 2010
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	==Institutions==		==Institutions==
-	~~In the Sanger Institute, I am associated with several proteomics projects (stem cell biology, pathogen proteomics, etc.) and develop computational tools for systems biology and mass spectrometry.~~

-	Cologne University Bioinformatics Centre (CUBIC) ~~was~~ one of the highly funded bioinformatics facilities in the world and the quality of research is exceptional in its class. Besides, I have also been selected for the international Ph.D. program offered by [http://www.mpiz-koeln.mpg.de/english/studentInformation/IMPRScologne/index.html International Max Planck Research School] (IMPRS) which involves competitive selection strategies. The scientific, social and career oriented training offered by this program helps the students to compete in international level.	+
		+	In the '''Sanger Institute''', I am currently associated with the Genome dynamics and Evolution group, and working on genomics of rare diseases.
		+
		+	I had also been associated with several proteomics projects (stem cell biology, pathogen proteomics, etc.) and develop computational tools for systems biology and mass spectrometry.
		+
		+	I did my PhD in '''Cologne University Bioinformatics Centre (CUBIC)''', one of the highly funded bioinformatics facilities in the world and the quality of research there is exceptional in its class. Besides, I have also been selected for the international Ph.D. program offered by [http://www.mpiz-koeln.mpg.de/english/studentInformation/IMPRScologne/index.html International Max Planck Research School] (IMPRS) which involves competitive selection strategies. The scientific, social and career oriented training offered by this program helps the students to compete in international level.

	==Research==		==Research==

Parthi: /* Research Interests */

2010-03-19T12:00:52Z

Research Interests

←Older revision		Revision as of 12:00, 19 March 2010
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	== Research Interests ==		== Research Interests ==

-	* Computational Proteomics / Mass Spectrometry	+	* Genomics of rare diseases, cancers, etc.
		+	* Computational Proteomics / Mass Spectrometry / Systems Biology
	* Protein engineering and stability		* Protein engineering and stability
	* Protein-protein docking		* Protein-protein docking

Parthi: /* Research */

2010-03-19T11:59:39Z

Research

←Older revision		Revision as of 11:59, 19 March 2010
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	==Research==		==Research==

-	I am ~~currently working on computational proteomics and mass spectrometry~~ in the '~~Proteomic Mass Spectrometry~~' group in the Sanger Institute.	+	I am a '''Computational/Statistical biologist''' in the '''Genome Dynamics and Evolution''' group in the Sanger Institute located at the Wellcome Trust Genome Campus in Cambridge, UK. My current research deals with the genomics of rare diseases using the exome sequencing data, with special focus on detecting CNVs. I'll also be integrating my systems biology expertise to the genomic data.

-	As a member of the structural bioinformatics group at CUBIC, the main focus of my work was on computational prediction of protein structural stability. I have analysed and predicted the stability of proteins upon mutations. This study has a huge impact on the industrial applications for engineering thermostable protein mutants, analysing the protein stability upon mutations that cause diseases, etc. The prediction model involves statistical mechanics functions and thorough identification of protein structural factors and has direct implications on protein structure solutions, protein-protein/ligand docking and virtual screening of potential drug targets. The study involves statistical methods, mathematics, statistical mechanics and empirical approaches to manipulate the experimental data and to develop reliable protein engineering methods. I am familiar with statistical tools and libraries to do cluster analysis, PCA, normilization and various ~~linear~~ regressions methods.	+	I was working on computational proteomics and mass spectrometry in the 'Proteomic Mass Spectrometry' group in the Sanger Institute, and my work was on identifying/analysing post-translational modifications (especially phosphorylation) from the MS data using some of the latest algorithms, some of them developed in-house, as well as other algorithms.
		+
		+	As a member of the structural bioinformatics group at CUBIC, the main focus of my work was on computational prediction of protein structural stability. I have analysed and predicted the stability of proteins upon mutations. This study has a huge impact on the industrial applications for engineering thermostable protein mutants, analysing the protein stability upon mutations that cause diseases, etc. The prediction model involves statistical mechanics functions and thorough identification of protein structural factors and has direct implications on protein structure solutions, protein-protein/ligand docking and virtual screening of potential drug targets. The study involves statistical methods, mathematics, statistical mechanics and empirical approaches to manipulate the experimental data and to develop reliable protein engineering methods. I am familiar with statistical tools and libraries to do cluster analysis, PCA, normilization and various regressions methods.

	== Research Interests ==		== Research Interests ==

Parthi: /* Vijaya Parthiban's Page in OpeWetWare */

2009-07-06T11:09:59Z

Vijaya Parthiban's Page in OpeWetWare

←Older revision		Revision as of 11:09, 6 July 2009
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	I am a post doctoral computational biologist in the [http://www.sanger.ac.uk/ Wellcome Trust Sanger Institute] in Cambridge (UK). I did my Ph.D. and worked as a 'staff scientist' in [http://www.cubic.uni-koeln.de Colonge University Bioinformatics Center, Germany] before moving to Cambridge. I was selected for the Ph.D. program in the International Max Planck Research School in Cologne in 2002.		I am a post doctoral computational biologist in the [http://www.sanger.ac.uk/ Wellcome Trust Sanger Institute] in Cambridge (UK). I did my Ph.D. and worked as a 'staff scientist' in [http://www.cubic.uni-koeln.de Colonge University Bioinformatics Center, Germany] before moving to Cambridge. I was selected for the Ph.D. program in the International Max Planck Research School in Cologne in 2002.
		+	'''More details are available from my personal website: [http://www.parthi.net http://www.parthi.net]'''

	==Institutions==		==Institutions==

Parthi: /* Institutions */

2009-05-25T15:36:59Z

Institutions

←Older revision		Revision as of 15:36, 25 May 2009
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	In the Sanger Institute, I am associated with several proteomics projects (stem cell biology, pathogen proteomics, etc.) and develop computational tools for systems biology and mass spectrometry.		In the Sanger Institute, I am associated with several proteomics projects (stem cell biology, pathogen proteomics, etc.) and develop computational tools for systems biology and mass spectrometry.

-	~~My Ph.D. institution~~ (CUBIC~~, Cologne, Germany~~) was one of the highly funded bioinformatics facilities in the world and the quality of research is exceptional in its class. Besides, I have also been selected for the international Ph.D. program offered by IMPRS which involves competitive selection strategies. The scientific, social and career oriented training offered by this program helps the students to compete in international level.	+	Cologne University Bioinformatics Centre (CUBIC) was one of the highly funded bioinformatics facilities in the world and the quality of research is exceptional in its class. Besides, I have also been selected for the international Ph.D. program offered by [http://www.mpiz-koeln.mpg.de/english/studentInformation/IMPRScologne/index.html International Max Planck Research School] (IMPRS) which involves competitive selection strategies. The scientific, social and career oriented training offered by this program helps the students to compete in international level.

	==Research==		==Research==

Parthi: /* Vijaya Parthiban's Page in OpeWetWare */

2009-05-25T15:34:27Z

Vijaya Parthiban's Page in OpeWetWare

←Older revision		Revision as of 15:34, 25 May 2009
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	=Vijaya Parthiban's Page in OpeWetWare=		=Vijaya Parthiban's Page in OpeWetWare=

-	I am a post doctoral computational biologist in the Wellcome Trust Sanger Institute in Cambridge (UK). I did my Ph.D. and worked as a 'staff scientist' in [http://www.cubic.uni-koeln.de Colonge University Bioinformatics Center, Germany] before moving to Cambridge. I was selected for the Ph.D. program in the International Max Planck Research School in Cologne in 2002.	+	I am a post doctoral computational biologist in the [http://www.sanger.ac.uk/ Wellcome Trust Sanger Institute] in Cambridge (UK). I did my Ph.D. and worked as a 'staff scientist' in [http://www.cubic.uni-koeln.de Colonge University Bioinformatics Center, Germany] before moving to Cambridge. I was selected for the Ph.D. program in the International Max Planck Research School in Cologne in 2002.

	==Institutions==		==Institutions==

Parthi: /* Institution */

2009-05-25T15:32:30Z

Institution

←Older revision		Revision as of 15:32, 25 May 2009
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	I am a post doctoral computational biologist in the Wellcome Trust Sanger Institute in Cambridge (UK). I did my Ph.D. and worked as a 'staff scientist' in [http://www.cubic.uni-koeln.de Colonge University Bioinformatics Center, Germany] before moving to Cambridge. I was selected for the Ph.D. program in the International Max Planck Research School in Cologne in 2002.		I am a post doctoral computational biologist in the Wellcome Trust Sanger Institute in Cambridge (UK). I did my Ph.D. and worked as a 'staff scientist' in [http://www.cubic.uni-koeln.de Colonge University Bioinformatics Center, Germany] before moving to Cambridge. I was selected for the Ph.D. program in the International Max Planck Research School in Cologne in 2002.

-	==~~Institution~~==	+	==Institutions==
		+	In the Sanger Institute, I am associated with several proteomics projects (stem cell biology, pathogen proteomics, etc.) and develop computational tools for systems biology and mass spectrometry.

-	My institution (CUBIC) is one of the highly funded bioinformatics facilities in the world and the quality of research is exceptional in its class. Besides, I have also been selected for the international Ph.D. program offered by IMPRS which involves competitive selection strategies. The scientific, social and career oriented training offered by this program helps the students to compete in international level.	+	My Ph.D. institution (CUBIC, Cologne, Germany) was one of the highly funded bioinformatics facilities in the world and the quality of research is exceptional in its class. Besides, I have also been selected for the international Ph.D. program offered by IMPRS which involves competitive selection strategies. The scientific, social and career oriented training offered by this program helps the students to compete in international level.

	==Research==		==Research==

Parthi: /* Research Interests */

2009-05-13T13:04:58Z

Research Interests

←Older revision		Revision as of 13:04, 13 May 2009
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	* Computational Proteomics / Mass Spectrometry		* Computational Proteomics / Mass Spectrometry
	* Protein engineering and stability		* Protein engineering and stability
		+	* Protein-protein docking
	* Structural Bioinformatics		* Structural Bioinformatics
	* Drug discovery		* Drug discovery