Virginia United/2010/Readings

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===Synthetic Biology Overview===
===Synthetic Biology Overview===
#[http://www.nature.com/nbt/journal/v27/n12/abs/nbt1209-1099.html Building outside the box: iGEM and the BioBricks Foundation] and [http://www.nature.com/news/2010/100120/full/463288a.html Five hard truths for synthetic biology]
#[http://www.nature.com/nbt/journal/v27/n12/abs/nbt1209-1099.html Building outside the box: iGEM and the BioBricks Foundation] and [http://www.nature.com/news/2010/100120/full/463288a.html Five hard truths for synthetic biology]
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#Engineering microbes with synthetic biology frameworks
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#[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCW-4TT9VX3-4&_user=709070&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000039639&_version=1&_urlVersion=0&_userid=709070&md5=4c35b760f4d7e0a0483e26822771723c Engineering microbes with synthetic biology frameworks]
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#Synthetic biology: understanding biological design from synthetic circuits
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#[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VS2-4TX12FT-1&_user=709070&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1177214258&_rerunOrigin=google&_acct=C000039639&_version=1&_urlVersion=0&_userid=709070&md5=29ef36d56e441b840388272da47f9d01 Toward scalable parts families for predictable design of biological circuits] and [http://genomebiology.com/2009/10/11/114 Evolution, ecology and the engineered organism: lessons for synthetic biology]
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#Genome engineering
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#[http://www.nature.com/nrg/journal/v10/n12/abs/nrg2697.html Synthetic biology: understanding biological design from synthetic circuits]
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#Next-generation synthetic gene networks
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#[http://www.nature.com/nbt/journal/v27/n12/abs/nbt.1591.html Next-generation synthetic gene networks]
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#Toward scalable parts families for predictable design of biological circuits
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#[http://www.nature.com/nbt/journal/v27/n12/full/nbt.1590.html Genome engineering]
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#Frameworks for programming biological function through RNA parts and devices
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#[http://www.cell.com/trends/biotechnology/abstract/S0167-7799(08)00285-0 Gene synthesis demystified]
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#Gene synthesis demystified  
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<br />
<br />
===Foundational and Fundamental Synthetic Biology===
===Foundational and Fundamental Synthetic Biology===
#[http://www.nature.com/nature/journal/v403/n6767/full/403339a0.html Construction of a genetic toggle switch in Escherichia coli ]
#[http://www.nature.com/nature/journal/v403/n6767/full/403339a0.html Construction of a genetic toggle switch in Escherichia coli ]
#[http://www.nature.com/nature/journal/v403/n6767/full/403335a0.html A synthetic oscillatory network of transcriptional regulators]
#[http://www.nature.com/nature/journal/v403/n6767/full/403335a0.html A synthetic oscillatory network of transcriptional regulators]
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#A modular and extensible RNA-based gene-regulatory platform for engineering cellular function
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#[http://www.pnas.org/content/104/36/14283.abstract A modular and extensible RNA-based gene-regulatory platform for engineering cellular function]
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#Synthesis of orthogonal transcription-translation networks
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#[http://www.pnas.org/content/106/21/8477.abstract Synthesis of orthogonal transcription-translation networks]
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#Refinement and standardization of synthetic biological parts and devices
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#[http://www.nature.com/nbt/journal/v26/n7/abs/nbt1413.html Refinement and standardization of synthetic biological parts and devices]
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#Setting the standard in synthetic biology
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#[http://www.nature.com/nbt/journal/v26/n7/full/nbt0708-771.html Setting the standard in synthetic biology]
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#Diversity-based model-guided construction of synthetic gene networks with predicted functions
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#[http://www.nature.com/msb/journal/v3/n1/full/msb4100185.html Accurate prediction of gene feedback circuit behavior from component properties]
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#Accurate prediction of gene feedback circuit behavior from component properties  
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<br />
<br />
===Advanced and Applied Synthetic Biology===
===Advanced and Applied Synthetic Biology===
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#[http://www.nature.com/msb/journal/v3/n1/full/msb4100173.html Environmental signal integration by a modular AND gate]
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#[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WK7-4HJRXGD-4&_user=709070&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000039639&_version=1&_urlVersion=0&_userid=709070&md5=6c9725dd0b7aa069916e7bd632c7f52c Environmentally controlled invasion of cancer cells by engineered bacteria]
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#[http://www.nature.com/nbt/journal/v27/n5/abs/nbt.1536.html Diversity-based model-guided construction of synthetic gene networks with predicted functions] and [http://www.nature.com/nbt/journal/v27/n5/full/nbt0509-450.html Overpowering the component problem]
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#[http://www.sciencemag.org/cgi/content/abstract/324/5931/1199 Synthetic gene networks that count]
#[http://www.nature.com/nbt/journal/v27/n10/abs/nbt.1568.html Automated design of synthetic ribosome binding sites to control protein expression]
#[http://www.nature.com/nbt/journal/v27/n10/abs/nbt.1568.html Automated design of synthetic ribosome binding sites to control protein expression]
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#Programming cells by multiplex genome engineering and accelerated evolution
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#[http://www.nature.com/nature/journal/v460/n7257/full/nature08187.html Programming cells by multiplex genome engineering and accelerated evolution]
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#Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
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#[http://www.nature.com/nbt/journal/v27/n8/abs/nbt.1557.html Synthetic protein scaffolds provide modular control over metabolic flux]
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#Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes
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#[http://www.nature.com/msb/journal/v5/n1/full/msb200962.html Engineering the Salmonella type III secretion system to export spider silk monomers]
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#Synthetic protein scaffolds provide modular control over metabolic flux
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#Engineering the Salmonella type III secretion system to export spider silk monomers
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#Synthetic Gene Networks That Count
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===Responses===
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#Environmentally controlled invasion of cancer cells by engineered bacteria
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*[[Virginia_United/2010/Readings/Responses/UVA|UVA]]
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#A synchronized quorum of genetic clocks
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Current revision

Virginia United 2010

Home        Schedule        Readings        Labs       

Synthetic Biology Overview

  1. Building outside the box: iGEM and the BioBricks Foundation and Five hard truths for synthetic biology
  2. Engineering microbes with synthetic biology frameworks
  3. Toward scalable parts families for predictable design of biological circuits and Evolution, ecology and the engineered organism: lessons for synthetic biology
  4. Synthetic biology: understanding biological design from synthetic circuits
  5. Next-generation synthetic gene networks
  6. Genome engineering
  7. Gene synthesis demystified


Foundational and Fundamental Synthetic Biology

  1. Construction of a genetic toggle switch in Escherichia coli
  2. A synthetic oscillatory network of transcriptional regulators
  3. A modular and extensible RNA-based gene-regulatory platform for engineering cellular function
  4. Synthesis of orthogonal transcription-translation networks
  5. Refinement and standardization of synthetic biological parts and devices
  6. Setting the standard in synthetic biology
  7. Accurate prediction of gene feedback circuit behavior from component properties


Advanced and Applied Synthetic Biology

  1. Environmental signal integration by a modular AND gate
  2. Environmentally controlled invasion of cancer cells by engineered bacteria
  3. Diversity-based model-guided construction of synthetic gene networks with predicted functions and Overpowering the component problem
  4. Synthetic gene networks that count
  5. Automated design of synthetic ribosome binding sites to control protein expression
  6. Programming cells by multiplex genome engineering and accelerated evolution
  7. Synthetic protein scaffolds provide modular control over metabolic flux
  8. Engineering the Salmonella type III secretion system to export spider silk monomers


Responses

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