W/F Red: Difference between revisions

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== Wednesday/Friday Red Presentation Page ==
== Wednesday/Friday Red Presentation Page ==
=== Overview ===
=== Overview ===
Our research aims to use gene therapy to mobilize bone marrow stem cells and RNAi to chemoattract the progenitor cells to damaged heart tissue with the goal of treating ischemic myopathy.
Our research aims to use gene therapy to mobilize bone marrow stem cells and RNAi to chemoattract the progenitor cells to damaged heart tissue with the goal of treating ischemic cardiomyopathy.


=== Background Research ===
=== Background Research ===

Revision as of 07:58, 4 May 2009

Wednesday/Friday Red Presentation Page

Overview

Our research aims to use gene therapy to mobilize bone marrow stem cells and RNAi to chemoattract the progenitor cells to damaged heart tissue with the goal of treating ischemic cardiomyopathy.

Background Research

Ischemic cardiomyopathy

Ischemic cardiomyopathy is a cause of congestive heart failure due to coronary artery disease. Ischemic refers the condition in which an organ does not obtain sufficent oxygen. Myopathy refers to a muscle related disease. Ischemic cardiomypoathy affects approximately 1 of 100 people in the United States.

Research Problem and Goals

Expected Results

Necessary Materials

Resources

  1. Zaruba, M-M. et al. "Synergy between CD26/DPP–IV inhibition and G–CSF improves cardiac function after acute myocardial infarction." Cell Stem Cell 4 313–323 (2009). http://www.ncbi.nlm.nih.gov/pubmed/19341621
  1. “Ischemic cardiomyopathy.” Medical Encyclopedia. 3 September 2008 http://www.nlm.nih.gov/medlineplus/ency/article/000160.htm