WangLab:Integrin Antibodies: Difference between revisions
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== Integrin Antibodies == | == Integrin Antibodies == | ||
*Wow-1, binds to high affinity unoccupied integrins | *Wow-1, binds to high affinity unoccupied integrins avb3, detecting affinity increase | ||
*LIBS-6,binds to occupied b3 and stablize it, therefore activate it, with high concentration 15ug/ml | *LIBS-6,binds to occupied b3 and stablize it, therefore activate it, with high concentration 15ug/ml | ||
*HUTS-21 , binds to occupied | *HUTS-21 , binds to occupied u1 and stablize it, activate | ||
*EDTA, specifically block binding to avb3. | *EDTA, specifically block binding to avb3. | ||
*16G3, block unoccupied FN sites (avb3, a5b1) | *16G3, block unoccupied FN sites (avb3, a5b1) | ||
Latest revision as of 11:31, 20 June 2007
Integrin Antibodies
- Wow-1, binds to high affinity unoccupied integrins avb3, detecting affinity increase
- LIBS-6,binds to occupied b3 and stablize it, therefore activate it, with high concentration 15ug/ml
- HUTS-21 , binds to occupied u1 and stablize it, activate
- EDTA, specifically block binding to avb3.
- 16G3, block unoccupied FN sites (avb3, a5b1)
- 3B8, block unoccupied FN sites (a5b1)
- 11E5, non-blocking control for 16G3, 3B8
- 661, blocking binding sites on Vitronectin for avb3
- 443, non-blocking control for 661.
- MnCl2, activates all the integrins (0.5mM).
