Warren Tourtellotte

Contact Info

Associate Professor, Pathology (Neuropathology), Neurology and Neuroscience
Director, Mouse Histology and Phenotyping Laboratory, Feinberg School of Medicine

Northwestern University
Feinberg School of Medicine
Department of Pathology
Ward Building 7-112
303 E. Chicago Ave.
Chicago, IL 60611
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Education

• Year, PhD, Institute
• Year, MS, Institute
• Year, BS, Institute

Research interests

• Animal Models of Human Disease
• Neuroscience
• Development
• Chromatin Structure/Gene Expression

Select Publications

1. Eldredge LC, Gao XM, Quach DH, Li L, Han X, Lomasney J, and Tourtellotte WG. Abnormal sympathetic nervous system development and physiological dysautonomia in Egr3-deficient mice. Development. 2008 Sep;135(17):2949-57. DOI:10.1242/dev.023960 |
2. Gao X, Daugherty RL, and Tourtellotte WG. Regulation of low affinity neurotrophin receptor (p75(NTR)) by early growth response (Egr) transcriptional regulators. Mol Cell Neurosci. 2007 Dec;36(4):501-14. DOI:10.1016/j.mcn.2007.08.013 |
3. Carter JH, Lefebvre JM, Wiest DL, and Tourtellotte WG. Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival. J Immunol. 2007 Jun 1;178(11):6796-805. DOI:10.4049/jimmunol.178.11.6796 |
4. Li L, Yun SH, Keblesh J, Trommer BL, Xiong H, Radulovic J, and Tourtellotte WG. Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory. Mol Cell Neurosci. 2007 May;35(1):76-88. DOI:10.1016/j.mcn.2007.02.004 |
5. Carter JH and Tourtellotte WG. Early growth response transcriptional regulators are dispensable for macrophage differentiation. J Immunol. 2007 Mar 1;178(5):3038-47. DOI:10.4049/jimmunol.178.5.3038 |
6. Li L, Carter J, Gao X, Whitehead J, and Tourtellotte WG. The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors. Mol Cell Biol. 2005 Dec;25(23):10286-300. DOI:10.1128/MCB.25.23.10286-10300.2005 |
7. Albert Y, Whitehead J, Eldredge L, Carter J, Gao X, and Tourtellotte WG. Transcriptional regulation of myotube fate specification and intrafusal muscle fiber morphogenesis. J Cell Biol. 2005 Apr 25;169(2):257-68. DOI:10.1083/jcb.200501156 |
8. Whitehead J, Keller-Peck C, Kucera J, and Tourtellotte WG. Glial cell-line derived neurotrophic factor-dependent fusimotor neuron survival during development. Mech Dev. 2005 Jan;122(1):27-41. DOI:10.1016/j.mod.2004.09.003 |
9. Chen HH, Tourtellotte WG, and Frank E. Muscle spindle-derived neurotrophin 3 regulates synaptic connectivity between muscle sensory and motor neurons. J Neurosci. 2002 May 1;22(9):3512-9. DOI:10.1523/JNEUROSCI.22-09-03512.2002 |
10. Tourtellotte WG, Keller-Peck C, Milbrandt J, and Kucera J. The transcription factor Egr3 modulates sensory axon-myotube interactions during muscle spindle morphogenesis. Dev Biol. 2001 Apr 15;232(2):388-99. DOI:10.1006/dbio.2001.0202 |
11. Tourtellotte WG, Nagarajan R, Bartke A, and Milbrandt J. Functional compensation by Egr4 in Egr1-dependent luteinizing hormone regulation and Leydig cell steroidogenesis. Mol Cell Biol. 2000 Jul;20(14):5261-8. DOI:10.1128/MCB.20.14.5261-5268.2000 |
12. Tourtellotte WG, Nagarajan R, Auyeung A, Mueller C, and Milbrandt J. Infertility associated with incomplete spermatogenic arrest and oligozoospermia in Egr4-deficient mice. Development. 1999 Nov;126(22):5061-71. DOI:10.1242/dev.126.22.5061 |
13. Tourtellotte WG and Milbrandt J. Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3. Nat Genet. 1998 Sep;20(1):87-91. DOI:10.1038/1757 |

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