X-Lab

X-Laboratory

(跨膜与感觉信号传导研究组)

Principle Investigator: Xiaodong Liu, Ph.D. (刘晓冬)

Department of Biomedical Engineering at Tsinghua University

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Welcome to the X-Lab! LAB DESCRIPTION Our lab is broadly interested in transmembrane and sesnory signaling based on channels, pursuing both biophysical mechanisms and bioengineering innovations. One of the most important signaling pathways to convey information from external world into biological systems is by way of channels sitting across the membrane. Such channels: could be cued by physical (e.g. voltage or photons) or chemical signals (e.g. ligand); could be natural channels (e.g. ion channels conductive to Ca2+ or K+) or engineered channels (e.g., nanopores by ultrasound). We focus on fundamental mechanisms critical to channel complexes involved in transmembrane signaling, especially those related to sensory functions, such as vision and taste. Representative work toward this direction refers to Liu X. et. al. Nature. Meanwhile, we actively explore the potentials of novel methodologies developped or derived from our basic research, such as sonoporation, channel modulators, biomolecular sensors etc. relevant publications (自然杂志 2010年) 新发现的依赖于钙离子，钙调素及压控钙离子通道相互作用的信号通路

X-LAB. Image by XXXXXX. The following positions are available: two postdoctoral positions; two positions of graduate students and one or two positions of technician. Please send email to Dr. Liu if you are interested. Include your CV and a brief description of your career goal. Starting date could be as early as 8/1/2010.