X-Lab

X-Laboratory

(跨膜与感觉信号转导研究组)

Principle Investigator: Xiaodong LIU, Ph.D. (刘晓冬)

Department of Biomedical Engineering, School of Medicine
School of Life Sciences
at Tsinghua University

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Welcome to the X-Lab! LAB DESCRIPTION Our lab is broadly interested in transmembrane and sensory signaling based on channels, pursuing both biophysical mechanisms and bioengineering innovations. One of the most important signaling pathways to convey information from external world into biological systems is by way of channels sitting across the membrane. Such channels: could be cued either by physical (e.g. voltage or photons) or by chemical signals (e.g. toxins or ions); could be either natural channels (e.g. ion channels conductive to Ca2+ or K+) or engineered channels (e.g., nanopores by ultrasound). We mainly focus on fundamental mechanisms critical to channel complexes involved in transmembrane signaling, especially those related to sensory functions, such as vision, taste, hearing and other less-studied modalities. Representative work toward this direction refers to Liu X. et. al. Nature. Meanwhile, we actively explore the potentials of novel methodologies developed or derived from our basic research, such as sonoporation, channel modulators, biomolecular sensors etc. relevant publications Lab News JIANG Peng from X-Lab presented research at Tsinghua BoShiShen Symposium of Life and Biomedical Sciences, Oct 15-16, 2011, Beijing X-Lab presented research at CaBP17, July 17-20, 2011, Beijing LIU Nan et al.(poster) XU Yanyan et al. (poster) LIU Xiaodong （invited talk) The X-lab is starting to accept PTN students for research rotations! http://life.tsinghua.edu.cn/home/announce/1613.html http://www.nibs.ac.cn/?act=view&id=2741 Postdoctoral Position Openings http://www.nature.com/naturejobs/science/jobs/191089-Postdoctoral-Fellow-Tsinghua-University X-Lab (LIU Qing, XIE Xin and LIU Xiaodong) presented the poster: CHARACTERIZATION OF QUANTITATIVE FRET SENSORS FOR FLUORESCENCE MOLECULAR TOMOGRAPHY Author Block: Qing Liu, Xin Xie, Yi Zhang, Yanyan Xu, Yue Zhang, Xin Liu, Jing Bai, Xiaodong Liu. Tsinghua University, Beijing, China. during Biophysics Society Annual Meeting, March 2011 at Baltimore, MD, USA Updates Individual Meetings (Starting from 2011/10) 17th “International Biophysics Congress” (IAPUB) Oct 30-Nov 3 Beijing, China http://www.17ibc.org/ 55th Annual Meeting of Biophysical Society March 5 - 9, 2011 http://www.biophysics.org/2012meeting 2011 ZHAO Shan (from Du Lab) 1/7 Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones LI Xuesong (from SONG Lab) 2/25 "Genetic dissection of an amygdala microcircuit that gates conditioned fear" and "Encoding of conditioned fear in central amygdala inhibitory circuits" LIU Nan 3/28 Salty Taste X-LAB. The following positions are currently available: Postdoctoral Fellows Ph.D. Students Masters' Students Please send email to Dr. Liu if you are interested. Include your CV and a brief description of your career goals. We also welcome undergraduate students (especially from major research universities in Beijing) to conduct research in our lab on thesis projects. All above positions can start immediately.