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神经科学与神经工程基础 (2012秋季)
神经科学与神经工程基础 (2012秋季)
Foundations of Neural Science & Engineering
Foundations of Neural Science & Engineering
(Fall 2012) 60 (48+12)
(Fall 2012) 60 (48+12)
上课时间: 每周三上午3小时 上课地点:清华大学 (教室:)
上课时间: 每周三上午3小时 上课地点:清华大学 (教室:)
讨论课时间: 周六,下午2小时 上课地点:清华大学 医学院 (教室待定)
讨论课时间: 周六,下午2小时 上课地点:清华大学 医学院 (教室待定)
课程负责人: 刘晓冬 <liuxiaodong@tsinghua.edu.cn>, 宋森 <sen.song@gmail.com>
课程负责人: 刘晓冬 <liuxiaodong@tsinghua.edu.cn>, 宋森 <sen.song@gmail.com>
助教:  
助教:  
教材:Foundations of Cellular Neurophysiology (Johnson and Wu, Q42 FJ72); Principles of Neural Sciences (Eric Kandel, R338 FP95);  
教材:Foundations of Cellular Neurophysiology (Johnson and Wu, Q42 FJ72); Principles of Neural Sciences (Eric Kandel, R338 FP95);  
参考书:Ion Channels of Excitable Membrane (Bertil Hille); Neural Engineering (2008, CRC Press, Q42 FN497); Neuroscience (Dale Purves, ISBN 978-0878936977, 医学馆) ; Neural Engineering (ISBN: 0585444684, MIT Press)
参考书:Ion Channels of Excitable Membrane (Bertil Hille); Neural Engineering (2008, CRC Press, Q42 FN497); Neuroscience (Dale Purves, ISBN 978-0878936977, 医学馆) ; Neural Engineering (ISBN: 0585444684, MIT Press)
E-resource: Principles of Neural Sciences; Ion Channels of Excitable Membrane; Neuroscience
E-resource: Principles of Neural Sciences; Ion Channels of Excitable Membrane; Neuroscience


Line 109: Line 118:


Introduction to Science and Engineering of Neural System
Introduction to Science and Engineering of Neural System
Course Coverage and General Introduction (1) Liu
Course Coverage and General Introduction (1) Liu
(basic principles, quantitative bend, engineering emphasis)
(basic principles, quantitative bend, engineering emphasis)


Neural System: Molecular, Cellular; (1) Liu                        Circuit and System. (1) Song
Neural System: Molecular, Cellular; (1) Liu                        Circuit and System. (1) Song
Discussion I. Liu and Song
Discussion I. Liu and Song


Neuronal Excitability
Neuronal Excitability
Electrical Properties of Neural Membrane: Membrane and HH Analysis (1) Liu
Electrical Properties of Neural Membrane: Membrane and HH Analysis (1) Liu
Ion Channels: Diversity and Physiology; Structure-Function: Single-Channel Analysis (2) Liu
Ion Channels: Diversity and Physiology; Structure-Function: Single-Channel Analysis (2) Liu
Discussion II. Liu
Discussion II. Liu


Realistic Neuron, pre- and post-synaptic mechanisms (2) Song
Realistic Neuron, pre- and post-synaptic mechanisms (2) Song
Cable Equation (1) Song
Cable Equation (1) Song
Neural Stimulation (1) Song
Neural Stimulation (1) Song
Discussion III. Song
Discussion III. Song


Functions of Nervous System
Functions of Nervous System
Sensory and Motor (3) Liu
Sensory and Motor (3) Liu
Discussion IV. Liu
Discussion IV. Liu


Cognitive: Learning, Memory and Emotion. (3) Song
Cognitive: Learning, Memory and Emotion. (3) Song
Discussion V. Song
Discussion V. Song



Revision as of 02:47, 20 March 2012

2012 Spring-I

PTN清华进展和讨论生物学专题讨论之细胞膜离子通道基础专题模块 (2012 Spring)

上课时间:3/6;3/8;3/13;3/15 上午8:50-10:35 上课地点:清华 六教 6B308

Contact Info:
Xiaodong Liu (刘晓冬), Ph.D.
Professor of Biomedical Engineering and Life Sciences
Principle Investigator of X-Lab 
http://openwetware.org/wiki/X-Lab
School of Medicine
Tsinghua University
B-307 (office); B-229(Lab)
Voice: (86)10-62796733 (O); 
TA: 秦 毅(2011级PTN学生) 邮箱:ptnqyi@126.com 手机:18210604223



Lecture I (3/6) : Fundamentals of Ion Channels

a. Current Understanding: Permeation; Selectivity; Gating

b. Historical Retrospects

c. Molecular Physiology of Ion Channels (Molecular Biophysics & Pathophysiological Relevance)


Lecture II (3/8) : Quantitative Descriptions o of Ion Channel Behaviors

a. H-H, (see http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1392413/pdf/jphysiol01442-0106.pdf)

b. Single Channels (see http://openwetware.org/images/1/18/Paper_Neher_Lecture.pdf)

c. Simulations (see http://www.neuron.yale.edu/neuron/)


Lecture III (3/13): Frontiers of Ion Channels -I

a. Molecular Aspects

Paper A: http://www.nature.com/nature/journal/v451/n7180/full/nature06529.html

Paper B: http://www.nature.com/nature/journal/v463/n7283/full/nature08766.html

b. Comments, Insights and Beyond (for non-channel proteins, see http://bernstein.harvard.edu/papers/peter_science_1998.pdf)


Lecture IV (3/15): Frontiers of Ion Channels -II

a. Physiological Aspects

Paper C: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature10812.html

Paper D: http://www.nature.com/nature/journal/v447/n7148/full/nature05865.html


b. Comments, Insights and Beyond (optogenetics, see http://en.wikipedia.org/wiki/Optogenetics)

c. Brief Summary


2012 Spring-II

医学药学实验班 生理学之神经生理I (2012 Spring)

2012.5.15 五 2 三教1209 sensory functions I

2012.5.28 二 3 三教1209 sensory functions II

Textbook: medical physiology chapter 31


2012 Fall-I

生物医学工程系本科 神经工程模块 (2012 Fall)


神经科学与神经工程基础,3学分,三上

(研究生秋季学期)

召集人: 刘晓冬

主讲:  刘晓冬、宋森


神经科学与神经工程基础 (2012秋季)

Foundations of Neural Science & Engineering

(Fall 2012) 60 (48+12)

上课时间: 每周三上午3小时 上课地点:清华大学 (教室:)

讨论课时间: 周六,下午2小时 上课地点:清华大学 医学院 (教室待定)

课程负责人: 刘晓冬 <liuxiaodong@tsinghua.edu.cn>, 宋森 <sen.song@gmail.com>

助教:

教材:Foundations of Cellular Neurophysiology (Johnson and Wu, Q42 FJ72); Principles of Neural Sciences (Eric Kandel, R338 FP95);

参考书:Ion Channels of Excitable Membrane (Bertil Hille); Neural Engineering (2008, CRC Press, Q42 FN497); Neuroscience (Dale Purves, ISBN 978-0878936977, 医学馆) ; Neural Engineering (ISBN: 0585444684, MIT Press)

E-resource: Principles of Neural Sciences; Ion Channels of Excitable Membrane; Neuroscience

(Syllabus)


Introduction to Science and Engineering of Neural System

Course Coverage and General Introduction (1) Liu

(basic principles, quantitative bend, engineering emphasis)

Neural System: Molecular, Cellular; (1) Liu Circuit and System. (1) Song

Discussion I. Liu and Song

Neuronal Excitability

Electrical Properties of Neural Membrane: Membrane and HH Analysis (1) Liu

Ion Channels: Diversity and Physiology; Structure-Function: Single-Channel Analysis (2) Liu

Discussion II. Liu

Realistic Neuron, pre- and post-synaptic mechanisms (2) Song

Cable Equation (1) Song

Neural Stimulation (1) Song

Discussion III. Song

Functions of Nervous System

Sensory and Motor (3) Liu

Discussion IV. Liu

Cognitive: Learning, Memory and Emotion. (3) Song

Discussion V. Song

Discussion VI. Liu and Song







2012 Fall-II

可兴奋细胞膜之离子通道

生物医学工程系 研究生选修课 (2012 Fall)