X:Research - Revision history

Xiaodong Liu at 06:57, 31 March 2012

Xiaodong Liu — Sat, 31 Mar 2012 06:57:50 GMT

←Older revision		Revision as of 06:57, 31 March 2012
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-	~~1. Sensory signaling via channel complex (''e.g.'', TRP/GPCR or Ca<SUB>V</SUB>/CaM).~~

-	~~2. Novel modulators of Ca<SUP>2+</SUP>~~ channels ~~as tools to pursue molecular physiology~~.	+	Our lab is broadly interested in transmembrane and sensory signaling based on channels, pursuing both biophysical mechanisms and bioengineering innovations.

-	~~3. Design and application~~ of ~~genetically encoded~~ (~~optical~~) sensors.	+	One of the most important signaling pathways to convey information from external world into biological systems is by way of channels sitting across the membrane. Such channels: could be cued either by physical (e.g. voltage or photons) or by chemical signals (e.g. toxins or ions); could be either natural channels (e.g. ion channels conductive to Ca<sup>2+</sup> or K<sup>+</sup>) or engineered channels (e.g., nanopores by ultrasound). We mainly focus on fundamental mechanisms critical to channel complexes involved in transmembrane signaling, especially those related to sensory functions, such as vision, taste, hearing and other less-studied modalities. Representative work toward this direction refers to [http://www.nature.com/nature/journal/v463/n7283/full/nature08766.html '''Liu X.''' ''et. al.'' '''Nature''']. Meanwhile, we actively explore the potentials of novel methodologies developed or derived from our basic research, such as biomolecular sensors and actuators. [http://openwetware.org/wiki/User:Xiaodong_Liu#Publications relevant publications]

-	~~in collaboration with [http://bme.tsinghua.edu.cn Dr. BAI Jing at Tsinghua University]~~

-	~~4. Mechanisms and engineering of membrane nanoporation.<br>~~
-
-	~~in collaboration with Beijing Institute of Medical Devices~~

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		+

Xiaodong Liu at 10:10, 26 December 2010

Xiaodong Liu — Sun, 26 Dec 2010 10:10:00 GMT

←Older revision		Revision as of 10:10, 26 December 2010
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	4. Mechanisms and engineering of membrane nanoporation.<br>		4. Mechanisms and engineering of membrane nanoporation.<br>

-	(in collaboration with Beijing Institute of Medical Devices)	+	in collaboration with Beijing Institute of Medical Devices

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Xiaodong Liu at 10:09, 26 December 2010

Xiaodong Liu — Sun, 26 Dec 2010 10:09:41 GMT

←Older revision		Revision as of 10:09, 26 December 2010
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	3. Design and application of genetically encoded (optical) sensors.		3. Design and application of genetically encoded (optical) sensors.

-	[http://bme.tsinghua.edu.cn ~~in collaboration with~~ Dr. BAI Jing at Tsinghua University]	+	in collaboration with [http://bme.tsinghua.edu.cn Dr. BAI Jing at Tsinghua University]

	4. Mechanisms and engineering of membrane nanoporation.<br>		4. Mechanisms and engineering of membrane nanoporation.<br>

Xiaodong Liu at 10:08, 26 December 2010

Xiaodong Liu — Sun, 26 Dec 2010 10:08:51 GMT

←Older revision		Revision as of 10:08, 26 December 2010
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	3. Design and application of genetically encoded (optical) sensors.		3. Design and application of genetically encoded (optical) sensors.
		+
	[http://bme.tsinghua.edu.cn in collaboration with Dr. BAI Jing at Tsinghua University]		[http://bme.tsinghua.edu.cn in collaboration with Dr. BAI Jing at Tsinghua University]
		+
	4. Mechanisms and engineering of membrane nanoporation.<br>		4. Mechanisms and engineering of membrane nanoporation.<br>
		+
	(in collaboration with Beijing Institute of Medical Devices)		(in collaboration with Beijing Institute of Medical Devices)

Xiaodong Liu at 10:08, 26 December 2010

Xiaodong Liu — Sun, 26 Dec 2010 10:08:22 GMT

←Older revision		Revision as of 10:08, 26 December 2010
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	3. Design and application of genetically encoded (optical) sensors.		3. Design and application of genetically encoded (optical) sensors.
-	[http://bme.tsinghua.edu.cn in collaboration with Dr. BAI Jing at Tsinghua University]	+	[http://bme.tsinghua.edu.cn in collaboration with Dr. BAI Jing at Tsinghua University]
	4. Mechanisms and engineering of membrane nanoporation.<br>		4. Mechanisms and engineering of membrane nanoporation.<br>
-	(in collaboration with Beijing Institute of Medical Devices)	+	(in collaboration with Beijing Institute of Medical Devices)

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Xiaodong Liu at 05:29, 19 November 2010

Xiaodong Liu — Fri, 19 Nov 2010 05:29:11 GMT

←Older revision		Revision as of 05:29, 19 November 2010
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	3. Design and application of genetically encoded (optical) sensors.		3. Design and application of genetically encoded (optical) sensors.
-	[http://bme.tsinghua.edu.cn in collaboration with Dr. BAI Jing at Tsinghua University)	+	[http://bme.tsinghua.edu.cn in collaboration with Dr. BAI Jing at Tsinghua University]
	4. Mechanisms and engineering of membrane nanoporation.<br>		4. Mechanisms and engineering of membrane nanoporation.<br>
	(in collaboration with Beijing Institute of Medical Devices)		(in collaboration with Beijing Institute of Medical Devices)

Xiaodong Liu at 05:28, 19 November 2010

Xiaodong Liu — Fri, 19 Nov 2010 05:28:51 GMT

←Older revision		Revision as of 05:28, 19 November 2010
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	3. Design and application of genetically encoded (optical) sensors.		3. Design and application of genetically encoded (optical) sensors.
-	(in collaboration with Dr. BAI Jing at Tsinghua University)	+	[http://bme.tsinghua.edu.cn in collaboration with Dr. BAI Jing at Tsinghua University)
	4. Mechanisms and engineering of membrane nanoporation.<br>		4. Mechanisms and engineering of membrane nanoporation.<br>
	(in collaboration with Beijing Institute of Medical Devices)		(in collaboration with Beijing Institute of Medical Devices)

Xiaodong Liu at 01:21, 19 November 2010

Xiaodong Liu — Fri, 19 Nov 2010 01:21:10 GMT

←Older revision		Revision as of 01:21, 19 November 2010
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	3. Design and application of genetically encoded (optical) sensors.		3. Design and application of genetically encoded (optical) sensors.
-		+	(in collaboration with Dr. BAI Jing at Tsinghua University)
	4. Mechanisms and engineering of membrane nanoporation.<br>		4. Mechanisms and engineering of membrane nanoporation.<br>
-		+	(in collaboration with Beijing Institute of Medical Devices)

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Xiaodong Liu at 08:57, 3 November 2010

Xiaodong Liu — Wed, 03 Nov 2010 08:57:50 GMT

←Older revision		Revision as of 08:57, 3 November 2010
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-	~~<font face="Helvetica" size=4>~~
-	~~Journal Club~~
-	~~</font><br>~~

Xiaodong Liu at 01:49, 27 October 2010

Xiaodong Liu — Wed, 27 Oct 2010 01:49:33 GMT

←Older revision		Revision as of 01:49, 27 October 2010
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-	~~2010~~

-	~~ZHANG Yue 8/12 FRET-based FMT~~
-
-	~~XU Yanyan 9/10 GPCR/Sensory Neuron~~
-
-	~~ZHAO Shan (from Du Lab) 9/25 Remotely Triggerable Drug Delivery Systems~~
-
-	~~LIU Qing 10/15 reversible photoswitchable rsTagRFP for pcFRET~~
-
-	~~YU Tao (from Song Lab) 10/22 Tetracycline-regulatable factors with distinct dimerization~~
-	~~domains allow reversible growth inhibition by p16~~
-
-	~~XIE Xin 10/29~~