Yan Yan Shery Huang

Profile

Yan Yan Shery Huang

Dr Yan Yan Shery Huang

• Department of Engineering, University of Cambridge
• Email me through OpenWetWare

I am a Lecturer (Assistant Professor) in Bioengineering leading the Biointerface Group, at Engineering for Life Sciences, Department of Engineering, University of Cambridge. Please see my interview with 'The Meaning of Success: Insights from Women at Cambridge'.

Research

*** A PhD studentship is available in creating in vitro model for brain cancer (UK/EU/non-EU)

• • • See project proposal 'Biomimetic Niche Model of Glioblastoma' link to studentship competition details

My research group is interested in designing and developing biomimetic niche for tissue engineering, and organ-on-chip for high-throughput drug testing.

Living tissues are intricate ensembles of multiple cell types embedded in a complex, but well-defined extracellular matrix (ECM) of topographical and adhesive features ranging from nanometres to micrometres. Cell ladened ECMs act like units of reaction centres and information hubs. Corporation between these small units lead to a hierarchical structure (i.e. a human body) achieving homeostasis (balance).

We combine nanotechnology and new material fabrication techniques to construct the defined biochemical and physical inputs of an ECM scaffold, and to recapitulate the key attributes of a 'niche' unit. Our research is highly multi-disciplinary in nature, crossing fields of engineering, biology, chemistry, polymer physics and computer science. We aim to translate our scientific findings into exploring a new generation of tissue engineering constructs for personalised therapy, at affordable costs; and to provide new solutions for disease monitoring, drug testing, and better patient healthcare.

Projects

Please visit my lab's webpage for further information about our research work. Research projects are available in the following areas:

• Organ-on-chips
• Neural stem cell engineering
• Vascular tissue engineering
• Tumor niche models
• ​Multi-material deposition of tissue engineering scaffold