Yeo lab:Projects

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
Line 4: Line 4:
|style="background:#ffffff"|
|style="background:#ffffff"|
-
One of the major obstacles in translating potent drug candidates from bench to bedside is delivery. For example, small interfering RNA (siRNA) has been recognized as a promising new class of drugs for viral infections, neurodegenerative diseases, and cancer; however, its therapeutic potential has not been realized because of the instability in circulation and inefficient delivery to the target cells. Target-specific delivery of anti-cancer drugs with minimal side effects on normal tissues has long been a goal for cancer therapy, but their clinical application remains challenging. Research topics in my lab will focus on developing drug/gene delivery systems which can address these challenges in ‘delivery.’ Specific projects involve (i) addressing the obstacles in siRNA delivery using formulation approaches, (ii) developing nanoparticles which mimic leukocyte-rolling behavior for tumor targeting, and (iii) developing inhalable microparticles which allows for delivering combinations of drugs for cystic fibrosis therapy.
+
Under construction
|}<br style="clear:both" />
|}<br style="clear:both" />

Revision as of 00:54, 14 January 2007

Laboratory for Therapeutic Particle Engineering

Home        Research        Publications        Lab Members        Positions        Contact        Links        Internal       

Under construction


Personal tools