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We are very grateful for Professor Yingjin Yuan, Professor Wei Li and Assistant Professor Xiaobin Fan. They provided us with generous guidance and research resources.

Thanks to Adam Marblestone and Mingjie Dai from Harvard University who came so far and worked with us for one week.

Thanks to Professor Dan Luo from Cornell University for his advice on our project


Main References

DNA logic gate

  • Liu J, Lu Y, A DNAzyme Catalytic Beacon Sensor for Paramagnetic Cu2+ Ions in Aqueous Solution with High Sensitivity and Selectivity[J], J. Am. Chem. Soc., 2007(129): 9838-9839.
  • Wang H, Kim Y, Liu H, Zhu Z, Bamrungsap S, Tan W, Engineering a Unimolecular DNA-Catalytic Probe for Single Lead Ion Monitoring[J], J. Am. Chem. Soc., 2009(131): 8221–8226.
  • Stojanovic M N, Stefanovic D, A deoxyribozyme-based molecular automaton[J], Nature Biotechnology, 2003(21): 1069-1074.


  • Um S H, Lee J B, Park N, Kwon S Y, Umbach C C, Luo D, Enzyme-catalysed assembly of DNA hydrogel[J], Nature Materials, 2006(5): 797-801.

The Origami Amplifier

  • Harvard BIOMOD 2011 wiki

Strongly Recommended Reading

DNA logic gate

  • Penchovsky R, Braker R R, Computational design and experimental validation of oligonucleotide-sensing allosteric ribozymes[J], Nature Biotechnology, 2005(23): 1424-1433.
  • Stojanovic M N, Stefanovic´ D, Deoxyribozyme-Based Half-Adder[J], J. Am. Chem. Soc., 2003(125): 6673-6676.
  • Macdonald J, Li Y, Sutovic M, Lederman H, Pendri K, Lu W, Andrews B L, Stefanovic D, Stojanovic M N, Medium Scale Integration of Molecular[J], Nano Letters, 2006(6): 2598-2603.


  • Park N, Um S H, Funabashi H, Xu J, Luo D, A cell-free protein-producing gel[J], Nature Materials, 2009(8): 432-437
  • Li Y, Tseng Y D, Kwon S Y, Espaux L D, Bunch J S, Mceuen P L, Luo D, Controlled assembly of dendrimer-like DNA, Nature Materials, 2004(3): 38-42.

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