Haynes Lab:Notebook/Engineering PC-TFs

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Project Description/Abstract

  • Synthetic biology is an exciting new field that aims to create novel biological functions by artificially combining natural molecular parts. Rational design allows us to engineer the behaviors of protein-based drugs, in ways that we cannot accomplish with small molecule-based drugs. DNA assembly will be used to build a combinatorial library of over 200 synthetic transcription factors (Pc-Tfs) that will potentially activate therapeutic genes in cancer and stem cells. As time allows, a select group of Pc-TF protein will be purified and analyzed biochemically.

Notes

  • Cameron Gardner's Spring/Fall 2014-2015 project in the Haynes Lab at Arizona State University.
  • Cameron was accepted into the Fulton Undergraduate Research Initiative (FURI) for the Spring, Summer, and Fall 2014 and Spring 2015 semesters.


Recent changes

25 December 2014

+      02:59 Haynes Lab:Notebook/Engineering PC-TFs‎ (2 changes) . . (+16) . . (Page history) [Cameron Lee Gardner‎ (2×)]

23 December 2014

+ N    19:13 Haynes Lab:Notebook/Engineering PC-TFs/2014/12/23‎ (2 changes) . . (+1,082) . . (Page history) [Cameron Lee Gardner‎ (2×)]
+ N    19:11 Haynes Lab:Notebook/Engineering PC-TFs/2014/12/22‎ (2 changes) . . (+1,026) . . (Page history) [Cameron Lee Gardner‎ (2×)]


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