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Our main interest is to better understand the cellular and molecular basis for generation and maintenance of regulatory T cells (Tregs) in the suppression of autoimmunities and/or allergies in mouse models. We have been using intravital microscopy as the starting point for the in vivo imaging of Tregs. The use of a multi-photon microscope, the development of new intravital surgical tecniques and tools, and use of animal models that develop autoimmune and allergic diseases, we are evaluating what and where the important cell-cell contacts for Tregs generation/function happen. We hope that a better comprehension of generation and function of these Tregs will be crucial for the development of new therapies against human autoimmune and allergic diseases. Our lab is located at the Unit of Cell Imaging, IGC, Portugal.

Publications

1. Maraver A, Tadokoro CE, Badura ML, Shen J, Serrano M, and Lafaille JJ. . pmid:17626841. PubMed HubMed [Paper1]
2. Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, and Littman DR. . pmid:16990136. PubMed HubMed [Paper2]
3. Tadokoro CE, Shakhar G, Shen S, Ding Y, Lino AC, Maraver A, Lafaille JJ, and Dustin ML. . pmid:16533880. PubMed HubMed [Paper3]
4. Shen S, Ding Y, Tadokoro CE, Olivares-Villagómez D, Camps-Ramírez M, Curotto de Lafaille MA, and Lafaille JJ. . pmid:16294223. PubMed HubMed [Paper4]
5. Martín AP, de Moraes LV, Tadokoro CE, Commodaro AG, Urrets-Zavalia E, Rabinovich GA, Urrets-Zavalia J, Rizzo LV, and Serra HM. . pmid:15914623. PubMed HubMed [Paper5]
6. Oliveira MA, Tadokoro CE, Lima GM, Mosca T, Vieira LQ, Leenen PJ, and Abrahamsohn IA. . pmid:15725387. PubMed HubMed [Paper6]
7. Pinge-Filho P, Peron JP, de Moura TR, Menolli RA, Graça VK, Estevão D, Tadokoro CE, Jankevicius JV, and Rizzo LV. . pmid:15585334. PubMed HubMed [Paper7]
8. Martins GA, Campanelli AP, Silva RB, Tadokoro CE, Russo M, Cunha FQ, Rizzo LV, and Silva JS. . pmid:15488732. PubMed HubMed [Paper8]
9. Eckley CA, Michelsohn N, Rizzo LV, Tadokoro CE, and Costa HO. . pmid:15467608. PubMed HubMed [Paper9]
10. Tadokoro CE, Vallochi AL, Rios LS, Martins GA, Schlesinger D, Mosca T, Kuchroo VK, Rizzo LV, and Abrahamsohn IA. . pmid:15324929. PubMed HubMed [Paper10]
11. Malvezi AD, Cecchini R, de Souza F, Tadokoro CE, Rizzo LV, and Pinge-Filho P. . pmid:15094169. PubMed HubMed [Paper11]
12. Martins GA, Tadokoro CE, Silva RB, Silva JS, and Rizzo LV. . pmid:15067068. PubMed HubMed [Paper12]
13. Tadokoro CE and de Almeida Abrahamsohn I. . pmid:11348667. PubMed HubMed [Paper13]
14. Grisotto MG, D'Império Lima MR, Marinho CR, Tadokoro CE, Abrahamsohn IA, and Alvarez JM. . pmid:11260326. PubMed HubMed [Paper14]
15. Pinge-Filho P, Tadokoro CE, and Abrahamsohn IA. . pmid:10202116. PubMed HubMed [Paper15]
16. Borges MM, Kloetzel JK, Andrade HF Jr, Tadokoro CE, Pinge-Filho P, and Abrahamsohn I. . pmid:9719432. PubMed HubMed [Paper16]
17. Tadokoro CE, Macedo MS, and Abrahamsohn IA. . pmid:8958049. PubMed HubMed [Paper17]

Useful links

• Introductory tutorial
• OpenWetWare help pages