IGEM:IMPERIAL/2006/project/Oscillator/Theoretical Analyses/Approach

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Analysis of the Model of the Molecular Predation Oscillator

Overview of Our Approach

  • Principle 1: Study of Ever More Complex Models
  • We took an incremental approach to the study of the 3D model.
  • Under a reasonable set of assumptions the 3D model can be turned into a 2D system.
  • We used this property fully as we built up our analysis towards that of the full 3D model:
- First we studied 2D models
- We started with Lotka-Volterra
- We increased the complexity of the model each time until we obtained the 2D model which equivalent to the 3D model (under the set of assumptions)
- See Result section for list of models
- If time permitting: the whole 3D Model
  • Breaking up the complexity of the 3D system in the way we did it had several notable advantages.
- It allowed us to learn the basics of Dynamical Systems Analysis and practice them on simple models.
- By modifying the various terms of the model we got a better understanding on how they interact with each other.
- It allowed us to learn from the previous calculations and thus to push them further in an effective manner.

Summary of our approach
Summary of our approach

  • Principle 2: Normalisation Effort for a System Analysis
In order to make our results easy to read and comprehend, we normalised the various steps of our analyses and the presentation of our results.
  • First page of the analysis: most important results
See the following template for the way we normalised
  • Following Pages: Display of important simulations (and comments)
see the following tutorial for a possible way to present simulation results
  • More detailed analyses are made available for downloading
Detailed analysis = proofs of results, full sets of simulations...
pdf and Doc suggested formats for attachments

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