IGEM:MIT/2009/Background Reading Materials

Phytochrome System Background

1. Sae Shimizu-Sato et al., “A light-switchable gene promoter system,” Nat Biotech 20, no. 10 (October 2002): 1041-1044. (PDF)

2. Gregory A. Gambetta and J. Clark Lagarias, “Genetic engineering of phytochrome biosynthesis in bacteria,” Proceedings of the National Academy of Sciences of the United States of America 98, no. 19 (2001): 10566-10571. (PDF)

3. Daisy W. Leung et al., “Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway,” Proceedings of the National Academy of Sciences 105, no. 35 (2008): 12797-12802. (PDF)

And here's a link to a vendor that sells biliverdin (precursor to PCB)... Fronteir Scientific, Inc.

4. Hoffman M., Gora M., Rytka J., "Identification of rate-limiting steps in yeast heme biosynthesis," Biochemical and Biophysical Research Communications 310 (2003) 1247-1253 (PDF)

5. Keng T., Alani E., Guarante L., "The Nine Amino-Terminal Residues of delta-Aminolevulinate Synthase Direct Beta-Galactosidase into the Mitochondrial Matrix," Mol. and Cell Bio. Vol. 6, No. 2, 355-364 (February 1986) (PDF)

6. Kohchi T et al , "Biosynthesis of chromophores for phytochrome and related photoreceptors," Plant Biotechnology 22, 409-413 (2005)

7. Bischoff M et al, "Excited-State Processes in Phycocyanobilin Studied by Femtosecond Spectroscopy," J. Phys. Chem. B 2000, 104, 1810-1816 (PDF)

8. Mukougawa K et al, "Metabolic engineering to produce phytochromes with phytochromobilin, phycocyanobilin, or phycoerythrobilin chromophore in Escherichia coli," FEBS Letters 580 (2006) 1333–1338 (PDF)

9. Frankenberg N, Lagarias JC, "Phycocyanobilin:Ferredoxin Oxidoreductase of Anabaena sp. PCC 7120," J. of Bio. Chem. Vol. 278, No. 11, Issue of March 14, pp. 9219–9226, 2003 (PDF)

10. Ni M, Tepperman JM, Quail PH, "Binding of phytochrome B to its nuclear signalling partner PIF3 is reversibly induced by light," Nature Vol. 400, 19 Aug 1999, pp. 781 - 784 (PDF)

11. Kim D et al., "Fungal Heme Oxygenases: Functional Expression and Characterization of Hmx1 from Saccharomyces cerevisiae and CaHmx1 from Candida albicans," Biochemistry 2006, 45, 14772-14780 (PDF)

12. Al-Sady B et al., "Photoactivated Phytochrome Induces Rapid PIF3 Phosphorylation Prior to Proteasome-Mediated Degradation," Molecular Cell 2006, 23, 439-446 (PDF)

13. Zhang L, Hach A, "Molecular mechanism of heme signaling in yeast: the transcriptional activator Hap1 serves as the key mediator," CMLS, Cell. Mol. Life Sci. 56 (1999) 415–426 (PDF)