Image:Knock-in&Knock out Mouse and Transgenic Mice.doc

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Knock-in&Knock_out_Mouse_and_Transgenic_Mice.doc (file size: 24 KB, MIME type: application/msword)

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The key difference between knock-in technology and transgenic technology is that a knock-in involves a gene inserted into a specific locus. Or, in other words, it is a "targeted" insertion, meaning the desired gene is inserted into a specific locus in the target genome via homologous recombination. This is important technique because it means the gene will achieve biological expression patterns and levels.

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current04:25, 18 March 2015 (24 KB)Hanah Cole (Talk | contribs) (The key difference between knock-in technology and transgenic technology is that a knock-in involves a gene inserted into a specific locus. Or, in other words, it is a "targeted" insertion, meaning the desired gene is inserted into a specific locus in the)

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