Protein Biotechnology:BIO501

Description CONTENTS Elements of Protein Biochemistry Ν. Μοschonas 3 hours Architectural elements of the genome, types of DNA sequences, genes coding for proteins, multi-gene families, structure-function relationships of proteins Μ. Κοkkinidis 6 hours Structural and physical chemical properties of proteins Enzyme Catalysis Κ. Petratos Introduction to Enzymes The chemical nature of enzymes and definitions of basic terms of enzymology Structural characteristics of known enzymes Enzyme Kinetics Basic Principles The 'Michaelis-Menten' Theory Definitions of kinetic parameters Estimation of kinetic parameters via plotting of appropriate functions Chemical kinetics of enzymatic reactions with multiple substrates Enzyme inhibition Analysis of the 'Hill' plots Regulation of enzymatic function Mechanisms of Enzymatic Catalysis General principles of enzymatic catalysis Vorgias CE Molecular Basis of some Genetic Diseases Contributions of the elucidation of the function of proteins Other