- It is useful to have independent control of cellular physical quantities.
- Outline of a system for controlling the mean and variance of protein expression population distributions.
- Ozbudak EM, Thattai M, Kurtser I, Grossman AD, and van Oudenaarden A. . pmid:11967532.
- Becskei A and Serrano L. . pmid:10850721.
- Swain PS. . pmid:15544806.
- Smolke CD, Carrier TA, and Keasling JD. . pmid:11097920.
- Carrier TA and Keasling JD. . pmid:9933514.
- Lamontagne B and Elela SA. . pmid:14581474.
- for more on the ideas of independence and reachability, look into control theory. Richard Murray at Caltech is working on a text, which is online: Feedback Systems - An Introduction for Scientists and Engineers. Also, the idea of observability is interesting to think about, in terms of what cellular processes we can study and understand.
- Also, the slides are best viewed with the soundtrack of MC Hammer's U Can't Touch This, a thoughtful piece on man's ability to use tools (symbolically the hammer) to manipulate and understand nature.
- please leave comments or feedback here: -Kelsic
- "sweetness is my weakness" - MC Hammer / Tsbayer