Stephanopoulos:ALSYSTA
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ALSYSTA - Systems Analysis Software for Win98, ME, 2k, NT & XP.Outline:ALSYSTA is a software suite that includes a series of tools for the analysis of different aspects of biological systems, such as the expression phenotype and the metabolic flux profiles of cells, as well as various tools to search web based databases. The "Projection" moiety uses either Principal Component Analysis (PCA) - with various filtering tools, or Fisher Discriminant Analysis (FDA), to project gene expression data into a reduced dimensional space. This enables one to find patterns and structure in the expression phenotype which can be used either to reduce the gene set into fewer discriminatory gene, or facilitate further analysis. With the "Metabolic Analysis" moiety it is possible to draw a reaction network, with detailed carbon transition information, and automatically generate a stoichiometry matrix from the drawing itself, which can then be passed on to external programs for tracer experiment simulation and analysis. Downloads:
Supporting Papers:
Sample Data Sets:
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