User:Andrew Perry

From OpenWetWare

Contents 1 Contact Info 2 Online 3 Education 4 Research interests 4.1 General techniques 4.2 Specific areas 4.3 Areas I haven't published in, but would like to do some work in 5 Publications 6 Some links to useful OWW (and other) resources 7 Generic OWW links

Contact Info

• Andrew Perry
• Department of Biochemistry and Molecular Biology
• Monash University, Clayton Campus,
• PO Box 13d, VIC, 3800, Australia.

• Email me through OpenWetWare

I'm currently a Postdoctoral Fellow in the Whisstock Lab, Department of Biochemistry and Molecular Biology, Monash University. Previously I worked in the Lithgow Lab when they were at the University of Melbourne; this group has since moved and is now one of the labs in the Host-Pathogen Molecular Biology Unit 'supergroup' at Monash University. I did my PhD under the supervision of Paul Gooley, doing NMR spectroscopy of proteins for structure determination.

Online

• I keep a personal blog about science, bioinformatics and the web.
• A lot of interesting links and discussion appears in The Life Scientists Room on FriendFeed. I lurk around and try to contribute to projects of the Biogang.

Education

• 2006, PhD, University of Melbourne
• 2001, BSc(Hon), University of Melbourne

Research interests

General techniques

1. Structural bioinformatics
2. Structural biology, NMR spectroscopy and X-ray crystallography
3. Outer membrane proteins

Specific areas

1. Outer mitochondrial and bacterial protein structure
2. Mitochondrial protein import
3. Beta-barrel membrane protein transport, folding, insertion and assembly
4. Web application development, and new technologies for scientific collaboration and information dissemination

Areas I haven't published in, but would like to do some work in

1. Synthetic biology (esp. compartmentalization of in vitro systems and directed evolution)
2. DNA computing and "in vivo" computation
3. Protein engineering
4. probably lots of other stuff .... gotta stay focused :) !!

Publications

1. Gentle IE, Perry AJ, Alcock FH, Liki? VA, Dolezal P, Ng ET, Purcell AW, McConnville M, Naderer T, Chanez AL, Charrière F, Aschinger C, Schneider A, Tokatlidis K, and Lithgow T. Conserved motifs reveal details of ancestry and structure in the small TIM chaperones of the mitochondrial intermembrane space. Mol Biol Evol 2007 May; 24(5) 1149-60. doi:10.1093/molbev/msm031 pmid:17329230. PubMed HubMed [perry1]
2. Liki? VA, Perry A, Hulett J, Derby M, Traven A, Waller RF, Keeling PJ, Koehler CM, Curran SP, Gooley PR, and Lithgow T. Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20. J Mol Biol 2005 Mar 18; 347(1) 81-93. doi:10.1016/j.jmb.2004.12.057 pmid:15733919. PubMed HubMed [perry2]
3. Perry AJ, Hulett JM, Liki? VA, Lithgow T, and Gooley PR. Convergent evolution of receptors for protein import into mitochondria. Curr Biol 2006 Feb 7; 16(3) 221-9. doi:10.1016/j.cub.2005.12.034 pmid:16461275. PubMed HubMed [perry3]
4. Perry AJ, Hulett JM, Lithgow T, and Gooley PR. 1H, 13C and 15N resonance assignments of the cytosolic domain of Tom20 from Arabidopsis thaliana. J Biomol NMR 2005 Nov; 33(3) 198. doi:10.1007/s10858-005-2325-8 pmid:16331427. PubMed HubMed [perry4]

All Medline abstracts: PubMed HubMed

Some links to useful OWW (and other) resources

• Open writing projects/Beginning Python for Bioinformatics ... a great resource in the making.
• University of Chicago:NMR Software Guide ... it's a bit like "NMRPipe: the missing manual".
• NMRWiki ... a growing NMR knowledge base.

• User:Andrew Perry/Web2.0 For Scientists -- "Emerging Tools for Scientific Collaboration Online". Some rough notes for a talk I may give one day.
• User:Andrew_Perry/Other_Bioscience_Wikis -- a list of other bioscience wikis and some commentary.

Generic OWW links

• Introductory tutorial
• OpenWetWare help pages