User:Daniel Mietchen/Notebook/Open Science/2011/03/05/Frontiers

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In the wake of the Guttenberg plagiarism case, I came across a free online tool for plagiarism detection that I had put to a test yesterday. Today, I performed some more tests on it, using three of my OA articles as examples.

Source article for this one: Mietchen D, Gaser C (2009) Computational morphometry for detecting changes in brain structure due to development, aging, learning, disease and evolution. Front Neuroinformatics 3:25. DOI:10.3389/neuro.11.025.2009 PMID: 19707517

Note: This article was drafted in part on-wiki, in the Citizendium pages Brain morphometry and Gyrification. The former of these has since been copied to Wikipedia.


Phrase Result Detail
Computational morphometry for detecting changes in brain structure due to development, aging, learning, disease and evolution |
Frontiers | | Frontiers in Neuroinformatics Mar 4, 2011 ... Computational morphometry for detecting changes in brain structure due to development, aging, learning, disease and evolution ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
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Frontiers | Oxygen-dependent gene expression in development and ... Mar 2, 2011 ... This action requires you to be registered with Frontiers and logged in. To register or login click here. Article Info. Abstract ... http://www.friendsoffrontiers.org/molecular_neuros... > Cached
To register or login click
Federated: Please Register or Login ... or an Institutional Investor in order to view this page. To register or login, click here. If you have any further questions please Contact Us. ... http://fiml.federatedinvestors.com/ > Cached
Computational morphometry for detecting changes in brain structure due to development, aging, learning, disease and evolution
Frontiers | | Frontiers in Neuroinformatics Mar 4, 2011 ... Computational morphometry for detecting changes in brain structure due to development, aging, learning, disease and evolution ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Structural Brain Mapping Group, Department of Psychiatry, University of Jena, D –
Christian Gaser, Ph.D. at Structural Brain Mapping Group Department of Psychiatry, University of Jena, Germany ... Structural Brain Mapping Group is powered by WordPress 3.0.5 and K2 ... http://dbm.neuro.uni-jena.de/people/christian-gase... > Cached
The brain, like any living tissue, is constantly changing in
Frontiers | | Frontiers in Neuroinformatics Mar 4, 2011 ... The brain, like any living tissue, is constantly changing in response to genetic and environmental cues and their interaction, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
response to genetic and environmental cues and their interaction, leading
Frontiers | | Frontiers in Neuroinformatics Mar 4, 2011 ... The brain, like any living tissue, is constantly changing in response to genetic and environmental cues and their interaction, leading to ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
to changes in brain function and structure, many of which
Frontiers | Computational morphometry for detecting changes in ... Feb 28, 2011... and their interaction, leading to changes in brain function and structure, many of which are now in reach of neuroimaging techniques. http://www.frontiersin.org/neuroinformatics/10.338... > Cached
has become the method of choice for studying macroscopic changes
Computational morphometry for detecting changes in brain structure ... Aug 11, 2009 ... Computational morphometry on the basis of Magnetic Resonance (MR) images has become the method of choice for studying macroscopic changes of ... http://www.ncbi.nlm.nih.gov/pubmed/19707517 > Cached
Thanks to computational advances and sophisticated study designs, both the
Computational morphometry for detecting changes in brain structure ... Aug 11, 2009 ... Thanks to computational advances and sophisticated study designs, both the minimal extent of change necessary for detection and, ... http://www.ncbi.nlm.nih.gov/pubmed/19707517 > Cached
minimal extent of change necessary for detection and, consequently, the
Computational morphometry for detecting changes in brain structure ... Aug 11, 2009... both the minimal extent of change necessary for detection and, consequently, the minimal periods over which such changes can be detected ... http://www.ncbi.nlm.nih.gov/pubmed/19707517 > Cached
minimal periods over which such changes can be detected have
Frontiers | | Frontiers in Neuroinformatics Mar 4, 2011... consequently, the minimal periods over which such changes can be detected have been reduced considerably during the last few years. http://www.frontiersin.org/neuroinformatics/10.338... > Cached
On the other hand, the growing availability of MR images
Computational morphometry for detecting changes in brain structure ... Aug 11, 2009 ... On the other hand, the growing availability of MR images of more and more diverse brain populations also allows more detailed inferences ... http://www.ncbi.nlm.nih.gov/pubmed/19707517 > Cached
of more and more diverse brain populations also allows more
Computational morphometry for detecting changes in brain structure ... Aug 11, 2009 ... On the other hand, the growing availability of MR images of more and more diverse brain populations also allows more detailed inferences ... http://www.ncbi.nlm.nih.gov/pubmed/19707517 > Cached
detailed inferences about brain changes that occur over larger time
Frontiers | | Frontiers in Neuroinformatics Mar 4, 2011... more detailed inferences about brain changes that occur over larger time scales, way beyond the duration of an average research project. http://www.frontiersin.org/neuroinformatics/10.338... > Cached
On this basis, a whole range of issues concerning the
Frontiers | | Frontiers in Neuroinformatics Mar 4, 2011 ... On this basis, a whole range of issues concerning the structures and functions of the brain are now becoming addressable, thereby providing ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
structures and functions of the brain are now becoming addressable,
Computational morphometry for detecting changes in brain structure ... Aug 11, 2009 ... On this basis, a whole range of issues concerning the structures and functions of the brain are now becoming addressable, thereby providing ... http://www.ncbi.nlm.nih.gov/pubmed/19707517 > Cached
thereby providing ample challenges and opportunities for further contributions from
Frontiers | | Frontiers in Neuroinformatics Mar 4, 2011... thereby providing ample challenges and opportunities for further contributions from neuroinformatics to our understanding of the brain ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
neuroinformatics to our understanding of the brain and how it
Frontiers | | Frontiers in Neuroinformatics Mar 4, 2011... contributions from neuroinformatics to our understanding of the brain and how it changes over a lifetime and in the course of evolution. http://www.frontiersin.org/neuroinformatics/10.338... > Cached
brain, or the number of neurons in it, as a
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... “It is tempting to take the volume of the brain, or the number of neurons in it, as a measure of its efficiency. Also, the relative sizes of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Also, the relative sizes of various subdivisions of the brain
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Also, the relative sizes of various subdivisions of the brain in different animal species (and even in individual human beings) are ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
These claims usually do not go much beyond the journalistic level
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The brain, like any living tissue, is constantly changing in response to genetic and environmental cues and their interaction, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
The central nervous system is a complex entity with an
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The central nervous system is a complex entity with an evolutionary history of over half a billion years that processes humongous amounts of ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
evolutionary history of over half a billion years that processes
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The central nervous system is a complex entity with an evolutionary history of over half a billion years that processes humongous amounts of ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
humongous amounts of internal and external information across multiple orders
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... years that processes humongous amounts of internal and external information across multiple orders of magnitude in time and space. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Consequently, a profound understanding of brain structures and functions (and
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Consequently, a profound understanding of brain structures and functions (and changes thereof) across scales can only be achieved by ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
changes thereof) across scales can only be achieved by integrating
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... a profound understanding of brain structures and functions (and changes thereof) across scales can only be achieved by integrating ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
insights from a range of experimental and theoretical approaches, which
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... achieved by integrating insights from a range of experimental and theoretical approaches, which poses a considerable challenge for both ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
poses a considerable challenge for both the generators and analyzers
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... and theoretical approaches, which poses a considerable challenge for both the generators and analyzers of the underlying data. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
interest, since their nature as a macroscopically observable ensemble property
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... Magnetic Resonance (MR) techniques are of particular interest, since their nature as a macroscopically observable ensemble property of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
of essentially subatomic origin makes them suitable as a bridge
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... since their nature as a macroscopically observable ensemble property of essentially subatomic origin makes them suitable as a bridge ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
between scales in space and time and applicable almost uniformly
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... them suitable as a bridge between scales in space and time and applicable almost uniformly across biological systems, living or not. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
These structural changes take place on longer time scales than
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... These structural changes take place on longer time scales than changes in brain function, which makes them robust indicators in clinical ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
changes in brain function, which makes them robust indicators in
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... These structural changes take place on longer time scales than changes in brain function, which makes them robust indicators in clinical ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
A brain morphometric study consists of two major components: First,
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... A brain morphometric study consists of two major components: First, a spatial representation of the brain or its components is obtained by ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
a spatial representation of the brain or its components is
Brain morphometry - Wikipedia, the free encyclopedia ... most studies in living subjects will by necessity have to use an indirect approach: A spatial representation of the brain or its components is obtained ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
obtained by repetitive application of some non-invasive neuroimaging technique (for
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... components is obtained by repetitive application of some non-invasive neuroimaging technique (for an overview of the available options, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
an overview of the available options, see Kim and Zee,
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... repetitive application of some non-invasive neuroimaging technique (for an overview of the available options, see Kim and Zee, 2007 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
This can be done with a number of different brains
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... This can be done with a number of different brains (a so-called cross-sectional study) or with one brain at several points in time (a ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
cross-sectional studies can provide supplementary information whose value outweighs
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... scales longer than a research project) cross-sectional studies can provide supplementary information whose value outweighs the effects ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
the effects of the additional source of error provided by
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... supplementary information whose value outweighs the effects of the additional source of error provided by interindividual variance. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Second, the morphometric measures can then be extracted from the
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Second, the morphometric measures can then be extracted from the image series and statistically analyzed, typically in the framework of a ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
image series and statistically analyzed, typically in the framework of
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Second, the morphometric measures can then be extracted from the image series and statistically analyzed, typically in the framework of a ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
a group comparison (for a comprehensive treatise, see Toga and
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... statistically analyzed, typically in the framework of a group comparison ( for a comprehensive treatise, see Toga and Mazziotta, 2002 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
The quantification of brain structural changes in time series of
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... The quantification of brain structural changes in time series of Magnetic Resonance (MR) images has previously been reviewed in detail, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Building on this foundation, we will provide an outline of
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Building on this foundation, we will provide an outline of more recent developments and highlight that, while the current focus of brain ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
more recent developments and highlight that, while the current focus
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Building on this foundation, we will provide an outline of more recent developments and highlight that, while the current focus of brain ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
of brain morphometry clearly is on clinically relevant changes, the
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... while the current focus of brain morphometry clearly is on clinically relevant changes, the computational approaches can also generate ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
computational approaches can also generate new insights into development, aging,
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... relevant changes, the computational approaches can also generate new insights into development, aging, learning and evolution. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Their integration with findings based on different methodologies and model
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Their integration with findings based on different methodologies and model systems provides ample challenges and opportunities on the way to ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
systems provides ample challenges and opportunities on the way to
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Their integration with findings based on different methodologies and model systems provides ample challenges and opportunities on the way to ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
an improved understanding of the relationships between brain structure and
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... ample challenges and opportunities on the way to an improved understanding of the relationships between brain structure and function. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
That these relationships are not obvious, is illustrated by Braitenberg’ s
Amazon.com: Vehicles: Experiments in Synthetic Psychology ... Braitenberg shows that these attributes and patterns of behavior can be .... and yet they are ultimately made up of "simple electro-mechanical relationships". ... Braitenburg could not be more obvious in the subtext of this book. ... http://www.amazon.com/Vehicles-Experiments-Psychol... > Cached
nuclei, of electromagnetic radiation at a frequency dependent upon the
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Magnetic Resonance (MR) is the selective absorption, by some atomic nuclei, of electromagnetic radiation at a frequency dependent upon the ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Dedicated protocols (MR pulse sequences) that vary these electromagnetic fields
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Dedicated protocols (MR pulse sequences) that vary these electromagnetic fields in a precise manner across space and time allow to record ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
in a precise manner across space and time allow to
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Dedicated protocols (MR pulse sequences) that vary these electromagnetic fields in a precise manner across space and time allow to record ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
record the three-dimensional distribution of these nuclei and some properties
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... and time allow to record the three-dimensional distribution of these nuclei and some properties of their physicochemical environment, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Image contrast can then be generated for specific purposes on
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Image contrast can then be generated for specific purposes on the basis of a selected subset of these properties, e.g. blood oxygenation for ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
blood oxygenation for functional MR imaging (Ogawa and Sung, 2007
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... e.g. blood oxygenation for functional MR imaging (Ogawa and Sung, 2007), diffusion for nerve fiber tracking (Hagmann et al., 2006), ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
relaxation characteristics for differentiating between different types of brain tissue (Mikulis and Roberts, 2007
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... brain morphometry – relaxation characteristics for differentiating between different types of brain tissue (Mikulis and Roberts, 2007; ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
thereof are gaining ground along with the spread of high-field
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Albeit approaches based on T2 or other contrasts and combinations thereof are gaining ground along with the spread of high-field MR imaging ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
In the wake of a wider availability of high-quality T1-weighted
Computational morphometry for detecting changes in brain structure ... Aug 11, 2009 ... In the wake of a wider availability of high-quality T1-weighted. MR images of diverse brain populations, MR-based brain mor- ... http://dbm.neuro.uni-jena.de/pdf-files/Mietchen-Fi... > Cached
MR images of diverse brain populations, MR-based brain morphometry has
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... In the wake of a wider availability of high-quality T1-weighted MR images of diverse brain populations, MR-based brain morphometry has ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Even within a given class of MR imaging protocols, however,
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Even within a given class of MR imaging protocols, however, details of the implementation can confound any analysis and have to be taken ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
details of the implementation can confound any analysis and have
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Even within a given class of MR imaging protocols, however, details of the implementation can confound any analysis and have to be taken ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
to be taken into account (for studies comparing different T1-weighted
Voxel-based morphometric multisite collaborative study on ... ... details of the implementation can confound any analysis and have to be taken into account (for studies comparing different T1-weighted pulse sequences, ... http://ukpmc.ac.uk/abstract/MED/18997157 > Cached
the volume of the brain, or the total number of neurons in it
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... As implied by Braitenberg (2007), measures on the whole-brain scale, e.g. the volume of the brain, or the total number of neurons in it1, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
, are the result of many different processes and will rarely reflect specific proficiencies
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... or the total number of neurons in it 1 , are the result of many different processes and will rarely reflect specific proficiencies. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
in various performances, it is hard to imagine how they
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... measured on several occasions) consistently differ in their proficiencies in various performances, it is hard to imagine how they could ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
could be structurally identical across all of their levels of
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... various performances, it is hard to imagine how they could be structurally identical across all of their levels of brain organization. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Taking advantage of the relatively high spatial resolution with respect
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Taking advantage of the relatively high spatial resolution with respect to other in vivo neuroimaging techniques, MR-based brain ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
to other in vivo neuroimaging techniques, MR-based brain morphometric measures
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... spatial resolution with respect to other in vivo neuroimaging techniques, MR -based brain morphometric measures now typically used are of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
the volume or thickness of the cerebral cortex in a
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... MR-based brain morphometric measures now typically used are of a local nature – e.g. the volume or thickness of the cerebral cortex in a ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
specific part of a gyrus, or the local extent of
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... or thickness of the cerebral cortex in a specific part of a gyrus, or the local extent of the cortical convolutions (i.e. gyrification) ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
and analyzed within a larger region of interest or even across the whole brain
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... of the cortical convolutions (i.e. gyrification) – and analyzed within a larger region of interest or even across the whole brain. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Indeed, it is often a whole-brain pattern of local-level structural
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Indeed, it is often a whole-brain pattern of local-level structural changes that distinguishes between groups of participants in a study or ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
changes that distinguishes between groups of participants in a study
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Indeed, it is often a whole-brain pattern of local-level structural changes that distinguishes between groups of participants in a study or ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
These measures are predominantly demographic but can, in principle, be
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... These measures are predominantly demographic but can, in principle, be any quantifiable phenotype hypothesized to be reflected in morphology ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
clinical diagnosis, medication or genotype
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... in principle, be any quantifiable phenotype hypothesized to be reflected in morphology, e.g. clinical diagnosis, medication or genotype. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
While many of these also modulate brain function, morphometric measures are more stable over time
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... While many of these also modulate brain function, morphometric measures are more stable over time. Preprocessing of MR images for brain ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
As pointed out above, MR images are generated by a
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... As pointed out above, MR images are generated by a complex interaction between static and dynamic electromagnetic fields and the tissue of ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
complex interaction between static and dynamic electromagnetic fields and the
Brain morphometry - Wikipedia, the free encyclopedia MR images are generated by a complex interaction between static and dynamic electromagnetic fields and the tissue of interest, namely the brain that is ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
the brain that is encapsulated in the head of the subject
Brain morphometry - Wikipedia, the free encyclopedia ... between static and dynamic electromagnetic fields and the tissue of interest , namely the brain that is encapsulated in the head of the subject. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Hence, the raw images contain noise from various sources –
Brain morphometry - Wikipedia, the free encyclopedia Hence, the raw images contain noise from various sources -- namely head movements (a scan suitable for morphometry typically takes on the order of 10 min) ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
In the following, the image is segmented into non-brain and
Brain morphometry - Wikipedia, the free encyclopedia In the following, the image is segmented into non-brain and brain tissue, with the latter usually being sub-segmented into at least gray matter (GM), ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
brain tissue, with the latter usually being sub-segmented into at
Brain morphometry - Wikipedia, the free encyclopedia In the following, the image is segmented into non-brain and brain tissue, with the latter usually being sub-segmented into at least gray matter (GM), ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
for a review of available segmentation methods, see Pham et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... matter (WM) and cerebrospinal fluid (CSF; for a review of available segmentation methods, see Pham et al., 2000 , see also Figure 1 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Since image voxels near the class boundaries do not generally
Brain morphometry - Wikipedia, the free encyclopedia Since image voxels near the class boundaries do not generally contain just one kind of tissue, partial volume effects ensue that can be corrected for. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
contain just one kind of tissue, partial volume effects ensue
Brain morphometry - Wikipedia, the free encyclopedia Since image voxels near the class boundaries do not generally contain just one kind of tissue, partial volume effects ensue that can be corrected for. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Several peaks –
A Particle Swarm Model for Tracking Multiple Peaks in a Dynamic ... Dynamic multimodal environments may change in several ways - peaks may shift spatially, change shape and change height. Note that a dynamic multimodal ... http://citeseerx.ist.psu.edu/viewdoc/download%3Fdo... > Cached
can be differentiated
PLoS ONE: Democrats and Republicans Can Be Differentiated from ... Citation: Rule NO, Ambady N (2010) Democrats and Republicans Can Be Differentiated from Their Faces. PLoS ONE 5(1): e8733. doi:10.1371/journal.pone. 0008733 ... http://www.plosone.org/article/info:doi/10.1371/jo... > Cached
In the next step, gaussian curves for each tissue class
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... In the next step, gaussian curves for each tissue class are fitted into the histogram to estimate the probability of a voxel belonging to ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
are fitted into the histogram to estimate the probability of
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... In the next step, gaussian curves for each tissue class are fitted into the histogram to estimate the probability of a voxel belonging to ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
using a Bayesian approach
Comparison of Spectra Using a Bayesian Approach. An Argument Using ... Dec 13, 2004 ... Comparison of Spectra Using a Bayesian Approach. An Argument Using Oil Spills as an Example. Abstract; HTML Full Text HTML; PDF ... http://pubs.acs.org/doi/abs/10.1021/ac048894j > Cached
are usually eliminated by registering the individual images to the
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... differences in brain shape are usually eliminated by registering the individual images to the stereotactic space of a template brain ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
This registration process also often involves a normalization of brain
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... This registration process also often involves a normalization of brain size, though this is not always desirable (e.g. when cortical ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
), and templates can be generated from the study’ s pool of brains (e
Brain morphometry - Wikipedia, the free encyclopedia These variables can then be mapped within the brain volume or on the brain surface, .... and templates can be generated from the study's pool of brains, ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Ashburner, 2007
A fast diffeomorphic image registration algorithm. Neuroimage. 2007 Oct 15;38(1):95-113. Epub 2007 Jul 18. A fast diffeomorphic image registration algorithm. Ashburner J. ... http://www.ncbi.nlm.nih.gov/pubmed/17761438 > Cached
Both the registered images and the deformation fields generated upon
Brain morphometry - Wikipedia, the free encyclopedia Both the registered images and the deformation fields generated upon registration can be used for morphometric analyses, thereby providing the basis for ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
registration can be used for morphometric analyses, thereby providing the
Brain morphometry - Wikipedia, the free encyclopedia Both the registered images and the deformation fields generated upon registration can be used for morphometric analyses, thereby providing the basis for ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
In the next section, we will briefly describe these three approaches to extract morphometric features from MR images
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... In the next section, we will briefly describe these three approaches to extract morphometric features from MR images. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
After the individual images were segmented, they are registered to the template
Brain morphometry - Wikipedia, the free encyclopedia After the individual images were segmented, they are registered to the template. Each voxel then contains a measure of the probability, according to which ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Each voxel then contains a measure of the probability, according to which it belongs to a specific segmentation class
Brain morphometry - Wikipedia, the free encyclopedia Each voxel then contains a measure of the probability, according to which it belongs to a specific segmentation class. For gray matter, this quantity is ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
For gray matter, this quantity is usually referred to as gray matter density
Brain morphometry - Wikipedia, the free encyclopedia For gray matter, this quantity is usually referred to as gray matter density ( GMD) or gray matter concentration (GMC), or gray matter probability (GMP). ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
In order to correct for the volume changes due to
Brain morphometry - Wikipedia, the free encyclopedia In order to correct for the volume changes due to the registration, the gray matter volume (GMV) in the original brain can be calculated by multiplying the ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
brain can be calculated by multiplying the GMD with the
Brain morphometry - Wikipedia, the free encyclopedia ... the gray matter volume (GMV) in the original brain can be calculated by multiplying the GMD with the Jacobian determinants of the deformations used to ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Jacobian determinants of the deformations used to register the brain
Brain morphometry - Wikipedia, the free encyclopedia ... original brain can be calculated by multiplying the GMD with the Jacobian determinants of the deformations used to register the brain to the template. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Class-specific volumes for WM and CSF are defined analogously
Brain morphometry - Wikipedia, the free encyclopedia Class-specific volumes for WM and CSF are defined analogously. The local differences in the density or volume of the different segmentation classes can then ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
The local differences in the density or volume of the
Brain morphometry - Wikipedia, the free encyclopedia The local differences in the density or volume of the different segmentation classes can then be statistically analyzed across scans and interpreted in ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
different segmentation classes can then be statistically analyzed across scans
Brain morphometry - Wikipedia, the free encyclopedia The local differences in the density or volume of the different segmentation classes can then be statistically analyzed across scans and interpreted in ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
), it provides an efficient tool to test or generate specific hypotheses about brain changes over time
Brain morphometry - Wikipedia, the free encyclopedia ... neuroimaging software packages (e.g. FSL and SPM), it provides an efficient tool to test or generate specific hypotheses about brain changes over time. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
), highly non-linear registration algorithms are used, and the statistical
Brain morphometry - Wikipedia, the free encyclopedia In DBM, highly non-linear registration algorithms are used, and the statistical analyses are not performed on the registered voxels but on the deformation ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
analyses are not performed on the registered voxels but on
Brain morphometry - Wikipedia, the free encyclopedia In DBM, highly non-linear registration algorithms are used, and the statistical analyses are not performed on the registered voxels but on the deformation ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
is based on the Jacobian determinant of the deformation matrix (Lepore et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... referred to as Tensor-based morphometry (TBM) – is based on the Jacobian determinant of the deformation matrix (Lepore et al., 2008 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
patient with schizophrenia at his first episode and after 7
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Left: This example shows two T1 images of a male patient with schizophrenia at his first episode and after 7 months. In the close-up views ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
In the close-up views at the bottom, the enlarged lateral
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... In the close-up views at the bottom, the enlarged lateral ventricles at the second time point can be clearly seen. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
The principle of DBM is to warp the second scan to the baseline scan by introducing high-dimensional deformations
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The principle of DBM is to warp the second scan to the baseline scan by introducing high-dimensional deformations. Once this is achieved, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Once this is achieved, the differences between both images are encoded in the deformations applied for the warp
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Once this is achieved, the differences between both images are encoded in the deformations applied for the warp. These deformations can then ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
These deformations can then be used to calculate volume changes by way of the Jacobian determinant
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... These deformations can then be used to calculate volume changes by way of the Jacobian determinant (right image). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Of course, multiple solutions exist for such non-linear warping procedures,
Brain morphometry - Wikipedia, the free encyclopedia Of course, multiple solutions exist for such non-linear warping procedures, and to balance appropriately between the potentially opposing requirements for ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
and to balance appropriately between the potentially opposing requirements for
Brain morphometry - Wikipedia, the free encyclopedia Of course, multiple solutions exist for such non-linear warping procedures, and to balance appropriately between the potentially opposing requirements for ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
global and local shape fit, ever more sophisticated registration algorithms
Brain morphometry - Wikipedia, the free encyclopedia ... between the potentially opposing requirements for global and local shape fit , ever more sophisticated registration algorithms are being developed. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Most of these, however, are computationally expensive if applied with a high-resolution grid
Brain morphometry - Wikipedia, the free encyclopedia Most of these, however, are computationally expensive if applied with a high- resolution grid. The biggest advantage of DBM with respect to VBM is its ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Furthermore, DBM and VBM can be considered a continuum in
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Furthermore, DBM and VBM can be considered a continuum in terms of the resolution of image registration algorithms, and so it is difficult ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
terms of the resolution of image registration algorithms, and so
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Furthermore, DBM and VBM can be considered a continuum in terms of the resolution of image registration algorithms, and so it is difficult ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
it is difficult to delineate a clear boundary between the
Bacterial contribution to manganese oxidation in a deep coastal ... For the same reason, it is difficult to delineate a clear boundary between the manganese oxidation and reduction zones in this sediment core. ... http://linkinghub.elsevier.com/retrieve/pii/027277... > Cached
two in practice, despite important differences in the underlying theoretical
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... a clear boundary between the two in practice, despite important differences in the underlying theoretical frameworks (Ashburner, 2007 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Due to the vast variety of registration algorithms, no widely
Brain morphometry - Wikipedia, the free encyclopedia However, due to the vast variety of registration algorithms, no widely accepted standard for DBM exists, which also prevented its incorporation into major ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
accepted standard for DBM exists, even though a number of
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Due to the vast variety of registration algorithms, no widely accepted standard for DBM exists, even though a number of stand-alone tools ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
compared with each other, and results are mapped back to
Surface-based morphometry - encyclopedia article - Citizendium Apr 9, 2010... sphere on which their original properties can be compared with each other, and results are mapped back to a reference brain surface. ... http://en.citizendium.org/wiki/Surface-based_morph... > Cached
The surfaces most appropriate for cortical analyses are the boundaries
Surface-based morphometry - encyclopedia article - Citizendium Apr 9, 2010 ... The surfaces most appropriate for cortical analyses are the boundaries between white and grey matter or between grey matter and ... http://en.citizendium.org/wiki/Surface-based_morph... > Cached
between WM and GM or between GM and CSF ,
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... The surfaces most appropriate for cortical analyses are the boundaries between WM and GM or between GM and CSF (the latter is also often ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
appropriate surfaces can be defined in a similar way, while
Surface-based morphometry - encyclopedia article - Citizendium Apr 9, 2010 ... For some subcortical structures (e.g. the hippocampus or basal ganglia), appropriate surfaces can be defined in a similar way, while lateral ... http://en.citizendium.org/wiki/Surface-based_morph... > Cached
Statistical analyses in SBM are based on properties of the individual mesh elements and aggregations thereof
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Statistical analyses in SBM are based on properties of the individual mesh elements and aggregations thereof. These latter ones include, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
These latter ones include, foremostly, some measure of the distance between different surfaces –
Surface-based morphometry - encyclopedia article - Citizendium Apr 9, 2010 ... These latter ones include, foremostly, some measure of the distance between different surfaces — typically the cortical thickness — or ... http://en.citizendium.org/wiki/Surface-based_morph... > Cached
, here shown not to be correlated with cortical thickness
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... here shown not to be correlated with cortical thickness in a large sample of adult male–male twin pairs), curvature (e.g. gyrification; ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
in a large sample of adult male– male twin pairs),
Dietary sodium intake in a sample of adult male population in ... Mar 10, 2010 ... sodium intake in a large unselected sample of adult male population in southern Italy. We found that the dietary ... http://www2.warwick.ac.uk/fac/med/staff/cappuccio/... > Cached
via spherical wavelets, spherical harmonics or Laplace-Beltrami spectra, cf
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Van Essen et al., 2006) or overall shape (e.g. via spherical wavelets, spherical harmonics or Laplace-Beltrami spectra, cf. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Niethammer et al
ZFIN: Publication: Niethammer et al., 2009. A tissue-scale ... PubMed: 19494811 Full text @ Nature · FIGURES (current status). ABSTRACT: Barrier structures (for example, epithelia around tissues and plasma membranes ... http://zfin.org/cgi-bin/webdriver%3FMIval%3Daa-pub... > Cached
rather stable property of a given brain, suitable for comparisons
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... fissuration or fissurization), a rather stable property of a given brain, suitable for comparisons across long time spans. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Gyrification refers to both the process and the extent of
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... In the brain sciences, gyrification refers to both the process and the extent of folding of the cerebral cortex in mammals as a consequence ... http://en.citizendium.org/wiki/Gyrification > Cached
folding of the mammalian cerebral cortex as a consequence of
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Gyrification refers to both the process and the extent of folding of the mammalian cerebral cortex as a consequence of brain growth during ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
The degree of folding can be quantified in multiple ways (cf
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... The degree of folding can be quantified in multiple ways (cf. Pienaar et al., 2008; Rodriguez-Carranza et al., 2008): Currently the most ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
): Currently the most popular is the slice-based gyrification index (GI
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Pienaar et al., 2008 ; Rodriguez-Carranza et al., 2008 ): Currently the most popular is the slice-based gyrification index (GI; Zilles et ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
It involves tracing the contour of the brain’ s surface
Fully Automatic Segmentation Of The Brain In MRI - Medical Imaging ... Our hybrid method is typical in that it involves some image processing steps first: ..... these slices a radiologist traced the brain contour manually, and ... http://citeseerx.ist.psu.edu/viewdoc/download%3Fdo... > Cached
outer contour) and is defined as the ratio between the complete and the outer contours within a given slice
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... (like the arachnoid mater; outer contour) and is defined as the ratio between the complete and the outer contours within a given slice. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Consequently, the more folded a surface, the higher its GI
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Consequently, the more folded a surface, the higher its GI. The GI can be averaged across slices and even across image orientations but it ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
The GI can be averaged across slices and even across
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The GI can be averaged across slices and even across image orientations but it cannot quantify local curvature, while some mesh-based ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
image orientations but it cannot quantify local curvature, while some
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The GI can be averaged across slices and even across image orientations but it cannot quantify local curvature, while some mesh-based ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
an example is the generalization of the GI from slice-based to surface-based contour ratios, as illustrated in Figure 3
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... measures can – an example is the generalization of the GI from slice-based to surface-based contour ratios, as illustrated in Figure 3 . ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
The traditional gyrification index can be calculated as the ratio
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The traditional gyrification index can be calculated as the ratio between the outer and inner contour of the cortex in coronal slices (upper ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
between the outer and inner contour of the cortex in
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The traditional gyrification index can be calculated as the ratio between the outer and inner contour of the cortex in coronal slices (upper ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Van Essen and Dierker, 2007
ARTICLE IN PRESS Comments and Controversies. On navigating the human cerebral cortex: Response to . 'in praise of tedious anatomy'. David C. Van Essen. ⁎ and Donna Dierker ... http://joedevlin.psychol.ucl.ac.uk/pubs/van_essen_... > Cached
) that provide, in principle, for an automated generation, analysis
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... AFNI SUMA 8 and the commercial BrainVoyager 9 ) that provide, in principle, for an automated generation, analysis and visualization of ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
and visualization of brain surface meshes and that perform reasonably
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... for an automated generation, analysis and visualization of brain surface meshes and that perform reasonably well on individual brains of ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Lyttelton et al
Humphrey Lyttelton Rare 7", 12" & Lp Vinyl Records & Humphrey ... HUMPHREY LYTTELTON et al Set Of Ten Caligraph LPs (Amazing straight run of numbers ONE TO TEN on Humphrey's own Caligraph label, a total of 110 tracks ... http://eil.com/shop/artistlist.asp%3Fartistname%3D... > Cached
Brain changes generally affect several levels of organization in the brain –
Question Everything: Brain Complexity at Multiple Scales Jan 6, 2011 ... One effect (7) reinforces the sensitivity of the post-synaptic compartment ... Generally only long distance axons (from one brain region to another) are sheathed. ... Synapses that strengthen due to high levels of activity at ..... the brain the changes have been based on simple modifications at one ... http://questioneverything.typepad.com/question_eve... > Cached
whose individual contributions are hard to disentangle at the spatial scales currently employed by MR-based morphometry
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... cellular one – whose individual contributions are hard to disentangle at the spatial scales currently employed by MR-based morphometry. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
The qualitatively largest changes within an individual occur during early
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The qualitatively largest changes within an individual occur during early development and more subtle ones during aging and learning, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
development and more subtle ones during aging and learning, whereas
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... during early development and more subtle ones during aging and learning, whereas pathological changes can vary highly in their extent, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
pathological changes can vary highly in their extent, and interindividual
Brain morphometry - Wikipedia, the free encyclopedia ... while pathological changes can vary highly in their extent and interindividual differences increase both during and across lifetimes. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
MR imaging has been applied to ever more brain populations
Brain morphometry - Wikipedia, the free encyclopedia ... and MR imaging has been applied to ever more brain populations relevant to these time scales, both within humans and across species. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
relevant to all of these time scales, both within humans
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... MR imaging has been applied to ever more brain populations relevant to all of these time scales, both within humans and across species, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
and across species, and the above-described morphometric methods provide the
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... both within humans and across species, and the above-described morphometric methods provide the means to analyze such changes ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
means to analyze such changes quantitatively on spatial scales in
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... and the above-described morphometric methods provide the means to analyze such changes quantitatively on spatial scales in the ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Currently, most applications of MR-based brain morphometry have a clinical focus (Mazziotta et al
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Currently, most applications of MR-based brain morphometry have a clinical focus (Mazziotta et al., 2000; Toga and Thompson, 2003), ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
they help to diagnose and monitor neuropsychiatric disorders, in particular neurodegenerative diseases on just two brain morphometric measures –
Brain morphometry - Wikipedia, the free encyclopedia Each voxel then contains a measure of the probability, according to which it belongs to a specific segmentation class. ... i.e. they help to diagnose and monitor neuropsychiatric disorders, in particular neurodegenerative diseases ( like ... Brain diseases are the field to which brain morphometry is most often ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
gray matter density as a relatively sensitive measure useful for
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... appropriate) on just two brain morphometric measures – gray matter density as a relatively sensitive measure useful for comparisons over ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
comparisons over shorter time scales and gyrification as a robust
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... comparisons over shorter time scales and gyrification as a robust structural property suitable for comparisons over large time scales. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Both are observable with existing methodologies, and both highlight, at
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Both are observable with existing methodologies, and both highlight, at different spatial scales, the multiple levels at which biological ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
different spatial scales, the multiple levels at which biological processes
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... at different spatial scales, the multiple levels at which biological processes interact to produce changes in brain structure. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
or shortly after birth, as in ferrets (Neal et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... development – in humans around mid-gestation (Armstrong et al., 1995 ) – or shortly after birth, as in ferrets (Neal et al., 2007 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
It proceeds synchronously in both hemispheres by an expansion of
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... It proceeds synchronously in both hemispheres by an expansion of gyral tissue, while the sulcal roots remain in a relatively stable position ... http://en.citizendium.org/wiki/Gyrification > Cached
In humans, all major gyri and sulci are usually present
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... In humans, all major gyri and sulci are usually present around birth, and gyrification reaches adult values around the age of 10 years ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
around birth, and gyrification reaches adult values around the age
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... In humans, all major gyri and sulci are usually present around birth, and gyrification reaches adult values around the age of 10 years ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
The primary effect of a folding process is always an increase of surface area relative to volume
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... The primary effect of a folding process is always an increase of surface area relative to volume. Due to the laminar arrangement of the ... http://en.citizendium.org/wiki/Gyrification > Cached
Due to the laminar arrangement of the cerebral cortex, an
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... Due to the laminar arrangement of the cerebral cortex, an increased cerebral surface area correlates with an increased number of neurons, ... http://en.citizendium.org/wiki/Gyrification > Cached
increased cortical surface area correlates with an increased number of
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Due to the laminar arrangement of the cerebral cortex, an increased cortical surface area correlates with an increased number of neurons ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
), which is presumed to enhance the computational capacities of
Gyrification - encyclopedia article - Citizendium Jul 28, 2010... of neurons, which is presumed to enhance the computational capacities of the cortex within some metabolic and connectivity limits. ... http://en.citizendium.org/wiki/Gyrification > Cached
the cortex within some metabolic and connectivity limits (Wen and
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... to enhance the computational capacities of the cortex within some metabolic and connectivity limits (Wen and Chklovskii, 2005 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
While the extent of cortical folding has been found to be partly determined by genetic factors (Kippenhan et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... While the extent of cortical folding has been found to be partly determined by genetic factors (Kippenhan et al., 2005 ; Kerjan and Gleeson, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
), the underlying biomechanical mechanisms are not yet well understood
Gyrification - encyclopedia article - Citizendium Jul 28, 2010... partly determined by genetic factors, the underlying biomechanical mechanisms are not yet well understood. The overall folding pattern, ... http://en.citizendium.org/wiki/Gyrification > Cached
The overall folding pattern, however, can be mechanistically explained in
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... The overall folding pattern, however, can be mechanistically explained in terms of the cerebral cortex buckling under the influence of ... http://en.citizendium.org/wiki/Gyrification > Cached
terms of the cerebral cortex buckling under the influence of
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... The overall folding pattern, however, can be mechanistically explained in terms of the cerebral cortex buckling under the influence of ... http://en.citizendium.org/wiki/Gyrification > Cached
Possible causes of the non-isotropy include differential growth of the
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... Possible causes of the non-isotropy include differential growth of the cortical layers due to variations in the number and timing of cell ... http://en.citizendium.org/wiki/Gyrification > Cached
cortical layers due to variations in the number and timing
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... Possible causes of the non-isotropy include differential growth of the cortical layers due to variations in the number and timing of cell ... http://en.citizendium.org/wiki/Gyrification > Cached
of cell divisions, cell migration, myelination, cortical connectivity, thalamic input,
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... layers due to variations in the number and timing of cell divisions, cell migration, myelination, cortical connectivity, thalamic input, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
MR imaging is rarely performed during pregnancy and the neonatal
Brain morphometry - Wikipedia, the free encyclopedia MR imaging is rarely performed during pregnancy and the neonatal period, in order to avoid stress for mother and child. In the cases of birth complications ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
In the cases of complications during pregnancy or birth, however, such data are being acquired
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... In the cases of complications during pregnancy or birth, however, such data are being acquired. Grossman et al. (2006) , for instance ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
, for instance, performed in utero MR-based brain volumetry and
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... (2006), for instance, performed in utero MR-based brain volumetry and found associations between different brain pathologies and ventricular ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
found associations between different brain pathologies and ventricular or parenchymal
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... in utero MR-based brain volumetry and found associations between different brain pathologies and ventricular or parenchymal volumes. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
analyzed gyrification in premature newborns at birth and found it
Brain morphometry - Wikipedia, the free encyclopedia Dubois et al., 2008, for instance, analyzed gyrification in premature newborns at birth and found it to be predictive of a functional score at ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Beyond preterms, there have been a number of large-scale longitudinal
Brain morphometry - Wikipedia, the free encyclopedia Beyond preterms, there have been a number of large-scale longitudinal MR- morphometric studies (often combined with cross-sectional approaches and other ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
MR-morphometric studies (often combined with cross-sectional approaches and other neuroimaging
Brain morphometry - Wikipedia, the free encyclopedia ... MR-morphometric studies (often combined with cross-sectional approaches and other neuroimaging modalities) of normal brain development in humans. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
modalities) of normal brain development in humans, most notably by
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... with cross-sectional approaches and other neuroimaging modalities) of normal brain development in humans, most notably by Giedd et al. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
and Thompson et al
P 8.1 An Update to the Supercell Composite and Significant Tornado ... and Thompson et al. 2004b, respectively. Other changes include the addition of a convective inhibition (CIN) term to the STP ... http://www.spc.noaa.gov/publications/thompson/stp_... > Cached
Using voxel-based and a number of complementary approaches, these studies revealed
Brain morphometry - Wikipedia, the free encyclopedia Using voxel-based and a number of complementary approaches, these studies revealed (or non-invasively confirmed, from the perspective of previous ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
from early development onto adolescence
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... (2006) , Lenroot and Giedd (2006) ; from early development onto adolescence. In order to interpret these findings, cellular processes have ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
In order to interpret these findings, cellular processes have to
Brain morphometry - Wikipedia, the free encyclopedia In order to interpret these findings, cellular processes have to be taken into consideration, especially those governing the pruning of axons, dendrites and ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
be taken into consideration, especially those governing the pruning of
Brain morphometry - Wikipedia, the free encyclopedia In order to interpret these findings, cellular processes have to be taken into consideration, especially those governing the pruning of axons, dendrites and ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
axons, dendrites and synapses (reviewed by Luo and O’ Leary,
Axon retraction and degeneration in development and disease. Luo L, O'Leary DD. Department of Biological Sciences, ... The selective elimination of axons, dendrites, axon and dendrite branches, and synapses, without loss of the ... Here we review examples of these phenomena and consider potential ... http://www.ncbi.nlm.nih.gov/pubmed/16022592 > Cached
) until an adult pattern of whole-brain connectivity is achieved
Brain morphometry - Wikipedia, the free encyclopedia ... dendrites and synapses until an adult pattern of whole-brain connectivity is achieved (which can best be monitored using diffusion-weighted techniques). ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
manifests itself in multiple ways (for reviews, see Cabeza et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Aging – the prototypical change over a lifetime – manifests itself in multiple ways (for reviews, see Cabeza et al., 2005 ; Raz and Rodrigue ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
) and possibly even the number of neurons (Pakkenberg et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... 2006 ) and possibly even the number of neurons (Pakkenberg et al., 2003 ) and some glial subpopulations (Pelvig et al., 2008 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Tisserand et al
New R Coronae Borealis stars discovered in OGLE-III Galactic Bulge ... Title: New R Coronae Borealis stars discovered in OGLE-III Galactic Bulge fields from their mid- and near- infrared properties. Authors: ... http://adsabs.harvard.edu/abs/2010arXiv1007.0800T > Cached
), they are hard to interpret at a mechanistic level
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... they are hard to interpret at a mechanistic level because the signal intensity in a voxel is a function of all these contributions, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
because the signal intensity in a voxel is a function
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... they are hard to interpret at a mechanistic level because the signal intensity in a voxel is a function of all these contributions, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
of all these contributions, and image registration is complicated by
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... is a function of all these contributions, and image registration is complicated by an age-related increase in morphological variability. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Age-associated changes in gyrification (albeit measurable
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Age-associated changes in gyrification (albeit measurable; Magnotta et al., 1999 ) face the same interpretational difficulties. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
) face the same interpretational difficulties
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Age-associated changes in gyrification (albeit measurable; Magnotta et al., 1999 ) face the same interpretational difficulties. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
It is thus clear that a deeper understanding of aging
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... It is thus clear that a deeper understanding of aging processes at the spatial scale of MR-based morphometry will require integration with ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
processes at the spatial scale of MR-based morphometry will require
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... It is thus clear that a deeper understanding of aging processes at the spatial scale of MR-based morphometry will require integration with ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
) as well as an extensive use of animal models (Toussaint et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... Raz and Rodrigue, 2006 ) as well as an extensive use of animal models ( Toussaint et al., 2000 ; Tapp et al., 2006 ; Alexander et al., ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
contrast agents
Contrast Agents Contrast agents, also known as contrast media, often are used during medical imaging examinations to highlight specific parts of the body and make them ... http://www.asrt.org/content/ThePublic/AboutRadiolo... > Cached
Perhaps the most profound impact to date of brain morphometry
Brain morphometry - Wikipedia, the free encyclopedia Perhaps the most profound impact to date of brain morphometry on our understanding of the relationships between brain structure and function has been ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
on our understanding of the relationships between brain structure and
Brain morphometry - Wikipedia, the free encyclopedia Perhaps the most profound impact to date of brain morphometry on our understanding of the relationships between brain structure and function has been ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
function has been provided by a series of VBM studies
Brain morphometry - Wikipedia, the free encyclopedia ... on our understanding of the relationships between brain structure and function has been provided by a series of VBM studies targeted at proficiency in ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
targeted precisely at proficiency in various performances: Licensed cab drivers
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... provided by a series of VBM studies targeted precisely at proficiency in various performances: Licensed cab drivers in London were found ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
in London were found to exhibit bilaterally increased gray matter
Brain morphometry - Wikipedia, the free encyclopedia ... performances: Licensed taxicab drivers in London were found to exhibit bilaterally increased gray matter volume in the posterior part of the hippocampus ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
volume in the posterior part of the hippocampus, both relative
Brain morphometry - Wikipedia, the free encyclopedia ... to exhibit bilaterally increased gray matter volume in the posterior part of the hippocampus, both relative to controls from the general population and ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
) and to London bus drivers matched for driving experience and stress levels (Maguire et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... 2000 ) and to London bus drivers matched for driving experience and stress levels (Maguire et al., 2006 , this study also reported an ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
, this study also reported an accompanying gray matter reduction in the anterior part of the hippocampus)
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... levels (Maguire et al., 2006 , this study also reported an accompanying gray matter reduction in the anterior part of the hippocampus). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Similarly, gray matter changes were also found to correlate with professional experience in musicians (Gaser and Schlaug, 2003
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Similarly, gray matter changes were also found to correlate with professional experience in musicians (Gaser and Schlaug, 2003; Azizi, 2009; ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
What is more, bilateral gray matter changes in the posterior
Brain morphometry - Wikipedia, the free encyclopedia What is more, bilateral gray matter changes in the posterior and lateral parietal cortex of medical students memorizing for an intermediate exam could be ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
and lateral parietal cortex of medical students memorizing for an
Brain morphometry - Wikipedia, the free encyclopedia What is more, bilateral gray matter changes in the posterior and lateral parietal cortex of medical students memorizing for an intermediate exam could be ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
intermediate exam could be detected over a period of just
Brain morphometry - Wikipedia, the free encyclopedia ... the posterior and lateral parietal cortex of medical students memorizing for an intermediate exam could be detected over a period of just three months. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
These studies of professional training inspired questions about the limits
Brain morphometry - Wikipedia, the free encyclopedia These studies of professional training inspired questions about the limits of MR -based morphometry in terms of time periods over which structural brain ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
of MR-based morphometry in terms of time periods over which
Brain morphometry - Wikipedia, the free encyclopedia These studies of professional training inspired questions about the limits of MR -based morphometry in terms of time periods over which structural brain ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Important determinants of these limits are the speed and spatial extent of the changes themselves
Brain morphometry - Wikipedia, the free encyclopedia Important determinants of these limits are the speed and spatial extent of the changes themselves. Of course, some events like accidents, a stroke, ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Of course, some events like accidents, a stroke, a tumor metastasis or a surgical intervention (cf
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Of course, some events like accidents, a stroke, a tumor metastasis or a surgical intervention (cf. Figure ​Figure4)4) can profoundly change ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
) can profoundly change brain structure during very short periods,
Brain morphometry - Wikipedia, the free encyclopedia ... some events like accidents, a stroke, a tumor metastasis or a surgical intervention can profoundly change brain structure during very short periods, ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
and these changes can be visualized with MR and other
Brain morphometry - Wikipedia, the free encyclopedia ... can profoundly change brain structure during very short periods, and these changes can be visualized with MR and other neuroimaging techniques. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Given the time constraints under such conditions, brain morphometry is
Brain morphometry - Wikipedia, the free encyclopedia Given the time constraints under such conditions, brain morphometry is rarely involved in diagnostics but rather used for progress monitoring over periods ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
rarely involved in diagnostics but rather used for progress monitoring
Brain morphometry - Wikipedia, the free encyclopedia Given the time constraints under such conditions, brain morphometry is rarely involved in diagnostics but rather used for progress monitoring over periods ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
over periods of weeks and months and longer (for an
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... for progress monitoring over periods of weeks and months and longer (for an overview with respect to stroke, see Makris et al., 2005). ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
DBM can be used to detect very subtle changes in the brain even in a single case
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... DBM can be used to detect very subtle changes in the brain even in a single case . In this example, T1-weighted images were acquired from a ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
This means that the primary motor cortex is unaffected by
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... This means that the primary motor cortex is unaffected by the prosthesis, while the somatosensory cortex reveals a small increase in volume ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
the prosthesis, while the somatosensory cortex reveals a small increase
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... This means that the primary motor cortex is unaffected by the prosthesis, while the somatosensory cortex reveals a small increase in volume ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
found that juggling novices showed a bilateral gray matter expansion
Brain morphometry - Wikipedia, the free encyclopedia One study found that juggling novices showed a bilateral gray matter expansion in the medial temporal visual area (also known as V5) over a three-month ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
in the medial temporal visual area (also known as V5)
Brain morphometry - Wikipedia, the free encyclopedia One study found that juggling novices showed a bilateral gray matter expansion in the medial temporal visual area (also known as V5) over a three-month ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
over a 3-month period during which they had learned to
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... area (also known as V5) over a 3-month period during which they had learned to sustain a three-ball cascade for at least a minute. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
No changes were observed in a control group that did not engage in juggling
Brain morphometry - Wikipedia, the free encyclopedia No changes were observed in a control group that did not engage in juggling. The extent of these changes in the jugglers reduced during a subsequent ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
The extent of these changes in the jugglers reduced during
Brain morphometry - Wikipedia, the free encyclopedia The extent of these changes in the jugglers reduced during a subsequent three- month period in which they did not practice juggling. To further resolve the ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
a subsequent 3-month period in which they did not practice
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The extent of these changes in the jugglers reduced during a subsequent 3-month period in which they did not practice juggling. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
To further resolve the time course of these changes, Driemeyer et al
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... To further resolve the time course of these changes, Driemeyer et al. (2008) repeated the experiment with another young cohort but scanned ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
repeated the experiment with another young cohort but scanned them
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... (2008) repeated the experiment with another young cohort but scanned them in shorter intervals, and the by then typical changes in V5 could ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
in shorter intervals, and the by then typical changes in
Brain morphometry - Wikipedia, the free encyclopedia ... the experiment was repeated with another young cohort scanned in shorter intervals, and the by then typical changes in V5 could already be found after ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
V5 could already be found after just 7 days of
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... scanned them in shorter intervals, and the by then typical changes in V5 could already be found after just 7 days of juggling practice. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Interestingly, the observed changes were larger in the initial learning phase than during continued training
Brain morphometry - Wikipedia, the free encyclopedia Interestingly, the observed changes were larger in the initial learning phase than during continued training. Whereas the former two studies involved ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Whereas the former two studies involved students in their early
Brain morphometry - Wikipedia, the free encyclopedia Whereas the former two studies involved students in their early twenties, the experiments were recently repeated with an elderly cohort, revealing the same ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
twenties, the experiments were recently repeated with an elderly cohort,
Brain morphometry - Wikipedia, the free encyclopedia Whereas the former two studies involved students in their early twenties, the experiments were recently repeated with an elderly cohort, revealing the same ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
revealing the same kind structural changes, although attenuated by lower
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... revealing the same kind structural changes, although attenuated by lower juggling performance of this group (Boyke et al., 2008). ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
application of Transcranial Magnetic Stimulation in daily sessions over 5 days –
Transcranial Magnetic Stimulation and Cranial Electrical Stimulation Patients received 5 consecutive days of active, low-frequency rTMS or ... The authors concluded that low-frequency rTMS administered over the .... The application of transcranial magnetic stimulation in psychiatry and neurosciences research. ... by five daily sessions of repetitive transcranial magnetic stimulation ... http://www.aetna.com/cpb/medical/data/400_499/0469... > Cached
observed changes in and near the TMS target areas as
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... (2007) observed changes in and near the TMS target areas as well as in the basal ganglia of volunteers in their mid-twenties, compared to a ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
well as in the basal ganglia of volunteers in their
Brain morphometry - Wikipedia, the free encyclopedia ... target areas as well as in the basal ganglia of volunteers in their mid- twenties, compared to a control group that had received placeboic TMS treatment. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
mid-twenties, compared to a control group that had received placeboic
Brain morphometry - Wikipedia, the free encyclopedia ... target areas as well as in the basal ganglia of volunteers in their mid- twenties, compared to a control group that had received placeboic TMS treatment. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
It is possible, though, that these changes simply reflect vascularization effects
Brain morphometry - Wikipedia, the free encyclopedia It is possible, though, that these changes simply reflect vascularization effects. Taken together, these morphometric studies strongly support the notion ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Taken together, these morphometric studies strongly support the notion that brain plasticity –
Brain morphometry - Wikipedia, the free encyclopedia Taken together, these morphometric studies strongly support the notion that brain plasticity -- changes of brain ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
) and may well be an adaptation to changes in
Brain morphometry - Wikipedia, the free encyclopedia ... remains possible throughout life and may well be an adaptation to changes in brain function which has also been shown to change with experience. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
brain function which has also been shown to change with
Brain morphometry - Wikipedia, the free encyclopedia ... remains possible throughout life and may well be an adaptation to changes in brain function which has also been shown to change with experience. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Golestani et al
Experience-dependant brain structural and functional plasticity in ... Sep 24, 2009... it has been shown that there is a more pronounced left > right asymmetry in parietal lobe white matter volumes (Golestani et al, ... http://virtualinstitute.eti.unige.ch/virtualinstit... > Cached
In other words, learning and plasticity provide two perspectives –
Child development - Wikipedia, the free encyclopedia Some aspects of child development are notable for their plasticity, ... characteristics cause other people to respond in certain ways, providing a ..... From around 18 months the child starts to combine words into two word sentences. .... Non word repetition and word learning: The nature of the relationship. ... http://en.wikipedia.org/wiki/Child_development > Cached
Brain diseases are the field to which brain morphometry is
Brain morphometry - Wikipedia, the free encyclopedia Brain diseases are the field to which brain morphometry is most often applied, and the volume of the literature on this is vast. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
most often applied, and the volume of the literature on
Brain morphometry - Wikipedia, the free encyclopedia Brain diseases are the field to which brain morphometry is most often applied, and the volume of the literature on this is vast. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
this is vast: For chronic schizophrenics alone, 19 VBM studies
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... and the volume of the literature on this is vast: For chronic schizophrenics alone, 19 VBM studies were recently reviewed by Williams ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
, and a review of our current understanding of schizophrenia makes heavy use of brain morphometric findings (DeLisi, 2008
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... and a review of our current understanding of schizophrenia makes heavy use of brain morphometric findings (DeLisi, 2008). ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
The situation is similar for Alzheimer’ s disease (Apostolova and Thompson, 2007
» When Alzheimers strikes: Five ways to respond | AdvisorAnalyst ... Feb 22, 2011 ... Here are five strategies you can use when Alzheimers strike a client's ... to tell clients that you've run into other situations similar to ... http://advisoranalyst.com/advisor/2011/02/22/when-... > Cached
polymicrogyria or lissencephalic disorders like agyria and pachygyria
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... exist of which abnormal gyrification is a dominant feature, e.g. polymicrogyria or lissencephalic disorders like agyria and pachygyria. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
, unilateral lissencephaly, have been described
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... They usually occur bilaterally but cases of, e.g., unilateral lissencephaly, have been described. Beyond these gross modifications of ... http://en.citizendium.org/wiki/Gyrification > Cached
Beyond these gross modifications of gyrification, more subtle variations occur
Gyrification - encyclopedia article - Citizendium Jul 28, 2010 ... Beyond these gross modifications of gyrification, more subtle variations occur in a number of neuropsychiatric disorders whose variety ... http://en.citizendium.org/wiki/Gyrification > Cached
in a number of neuropsychiatric disorders whose variety reflects the
Gyrification - encyclopedia article - Citizendium Jul 28, 2010... variations occur in a number of neuropsychiatric disorders whose variety reflects the multitude of processes underlying gyrification. ... http://en.citizendium.org/wiki/Gyrification > Cached
multitude of processes underlying gyrification (for overview, see Francis et
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... whose variety reflects the multitude of processes underlying gyrification ( for overview, see Francis et al., 2006; Razek et al., 2009). ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
MR-based morphometry of gyrification is gaining importance for clinical diagnostics,
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... MR-based morphometry of gyrification is gaining importance for clinical diagnostics, precisely because the cortical folding pattern is very ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
precisely because the cortical folding pattern is very stable throughout
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... precisely because the cortical folding pattern is very stable throughout adult life in non-patient populations (Armstrong et al., ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
This means that a deviation from normal gyrification rates has a high probability to indicate a brain malformation
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... This means that a deviation from normal gyrification rates has a high probability to indicate a brain malformation. As a result, a number of ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
As a result, a number of reports have been published
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... As a result, a number of reports have been published that found globally or regionally abnormal gyrification in a variety of disorders, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
that found globally or regionally abnormal gyrification in a variety
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... As a result, a number of reports have been published that found globally or regionally abnormal gyrification in a variety of disorders, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Brain changes also accumulate over periods longer than an individual
Brain morphometry - Wikipedia, the free encyclopedia Brain changes also accumulate over periods longer than an individual life but even though twin studies have established that human brain structure is highly ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
life but even though twin studies have established that human
Brain morphometry - Wikipedia, the free encyclopedia Brain changes also accumulate over periods longer than an individual life but even though twin studies have established that human brain structure is highly ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
), brain morphometric studies with such a broadened scope are rare
Brain morphometry - Wikipedia, the free encyclopedia ... brain morphometric studies with such a broadened scope are rare. However, in the context of disorders with a known or suspected hereditary component, ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
However, in the context of disorders with a known or
Brain morphometry - Wikipedia, the free encyclopedia However, in the context of disorders with a known or suspected hereditary component, a number of studies have compared the brain morphometry of patients ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
suspected hereditary component, a number of studies have compared the
Brain morphometry - Wikipedia, the free encyclopedia However, in the context of disorders with a known or suspected hereditary component, a number of studies have compared the brain morphometry of patients ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
brain morphometry of patients with both that of non-affected controls
Brain morphometry - Wikipedia, the free encyclopedia ... have compared the brain morphometry of patients with both that of non- affected controls and that of subjects at high risk for developing the disorder. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
and that of subjects at high risk for developing the
Brain morphometry - Wikipedia, the free encyclopedia ... have compared the brain morphometry of patients with both that of non- affected controls and that of subjects at high risk for developing the disorder. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
, a study identifying the GMD of the caudate nucleus
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... e.g., a study identifying the GMD of the caudate nucleus as correlating with the severity of verbal dyspraxia (Watkins et al., ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
as correlating with the severity of verbal dyspraxia (Watkins et
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... e.g., a study identifying the GMD of the caudate nucleus as correlating with the severity of verbal dyspraxia (Watkins et al., ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
) and a study that found thalamic GMD to differ
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... 2002) and a study that found thalamic GMD to differ between the parents of schizophrenics with, respectively, high and low genetic risks ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
between the parents of schizophrenics with, respectively, high and low
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... between the parents of schizophrenics with, respectively, high and low genetic risks for developing schizophrenia (Lui et al., 2009 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Even larger time gaps can be bridged by comparing human
Brain morphometry - Wikipedia, the free encyclopedia Even larger time gaps can be bridged by comparing human populations with a sufficiently long history of genetic separation, such as Central Europeans and ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
populations with a sufficiently long history of genetic separation, such
Brain morphometry - Wikipedia, the free encyclopedia Even larger time gaps can be bridged by comparing human populations with a sufficiently long history of genetic separation, such as Central Europeans and ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
One surface-based study compared the brain shape between these two
Brain morphometry - Wikipedia, the free encyclopedia One surface-based study compared the brain shape between these two groups and found a difference in their gender-dependent brain asymmetries. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
groups and found a difference in their gender-dependent brain asymmetries
Brain morphometry - Wikipedia, the free encyclopedia One surface-based study compared the brain shape between these two groups and found a difference in their gender-dependent brain asymmetries. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Neuroimaging studies of this kind, combined with functional ones and
Brain morphometry - Wikipedia, the free encyclopedia Neuroimaging studies of this kind, combined with functional ones and behavioural data, provide promising and so far largely unexplored avenues to understand ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
behavioural data, provide promising and so far largely unexplored avenues
Brain morphometry - Wikipedia, the free encyclopedia Neuroimaging studies of this kind, combined with functional ones and behavioural data, provide promising and so far largely unexplored avenues to understand ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
to understand similarities and differences between different groups of people
Brain morphometry - Wikipedia, the free encyclopedia ... behavioural data, provide promising and so far largely unexplored avenues to understand similarities and differences between different groups of people. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Whereas morphological analyses that compare brains at different ontogenetic or
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Whereas morphological analyses that compare brains at different ontogenetic or pathogenetic stages can reveal important information about ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
pathogenetic stages can reveal important information about normal or abnormal
Brain morphometry - Wikipedia, the free encyclopedia Like morphological analyses that compare brains at different ontogenetic or pathogenetic stages can reveal important information about normal or abnormal ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
development within a given species, cross-species comparative studies have a
Brain morphometry - Wikipedia, the free encyclopedia ... information about the progression of normal or abnormal development within a given species, cross-species comparative studies have a similar potential ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Three principle sources exist for comparative evolutionary investigations: Fossils, fresh-preserved post-mortem or in vivo studies
Brain morphometry - Wikipedia, the free encyclopedia Three principle sources exist for comparative evolutionary investigations: Fossils, fresh-preserved post-mortem or in vivo studies. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
The fossil record is dominated by structures that were already biomineralized during the lifetime of the respective organism
Brain morphometry - Wikipedia, the free encyclopedia The fossil record is dominated by structures that were already biomineralized during the lifetime of the respective organism (in the case of vertebrates, ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Brains, like other soft tissues, rarely fossilize, but occasionally they do
Brain morphometry - Wikipedia, the free encyclopedia Brains, like other soft tissues, rarely fossilize, but occasionally they do. The probably oldest vertebrate brain known today belonged to a ratfish that ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
The probably oldest vertebrate brain known today belonged to a
Brain morphometry - Wikipedia, the free encyclopedia The probably oldest vertebrate brain known today belonged to a ratfish that lived around 300 million years ago (Pradel et al., 2009). ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
ratfish that lived around 300 million years ago (Pradel et
Brain morphometry - Wikipedia, the free encyclopedia The probably oldest vertebrate brain known today belonged to a ratfish that lived around 300 million years ago (Pradel et al., 2009). ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
While the technique most widely used to image fossils is Computed Tomography (CT
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... While the technique most widely used to image fossils is Computed Tomography (CT ; reviewed in Zollikofer and Ponce de León, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
), this particular specimen was imaged by synchrotron tomography, and recent MR imaging studies with fossils (Mietchen et al
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... 2005), this particular specimen was imaged by synchrotron tomography, and recent MR imaging studies with fossils (Mietchen et al., ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
) suggest that this method can be used to image at least a subset of fossilized brains
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... studies with fossils (Mietchen et al., 2008 ) suggest that this method can be used to image at least a subset of fossilized brains. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
MR images have also been obtained from the brain of a 3200-year-old Egyptian mummy (Karlik et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... MR images have also been obtained from the brain of a 3200-year-old Egyptian mummy (Karlik et al., 2007 ), and MRI investigations of a ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
), and MRI investigations of a semi-fossil human brain
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... 2007), and MRI investigations of a semi-fossil human brain (aged over 2000 years) found at the Heslington site near York are currently ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
The perspectives are slim, however, that any three-dimensional imaging dataset
Brain morphometry - Wikipedia, the free encyclopedia The perspectives are slim, however, that any three-dimensional imaging dataset of a fossil, semi-fossil or mummified brain will ever be of much use to ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
of a fossil, semi-fossil or mummified brain will ever be
Brain morphometry - Wikipedia, the free encyclopedia The perspectives are slim, however, that any three-dimensional imaging dataset of a fossil, semi-fossil or mummified brain will ever be of much use to ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
of much use to morphometric analyses of the kind described
Brain morphometry - Wikipedia, the free encyclopedia ... semi-fossil or mummified brain will ever be of much use to morphometric analyses of the kind described here, since the processes of mummification and ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
here, since the processes of mummification and fossilization heavily alter
Brain morphometry - Wikipedia, the free encyclopedia ... of the kind described here, since the processes of mummification and fossilization heavily alter the structure of soft tissues in a way specific to the ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
the structure of soft tissues in a way specific to
Brain morphometry - Wikipedia, the free encyclopedia ... of mummification and fossilization heavily alter the structure of soft tissues in a way specific to the individual specimen and subregions therein. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Post-mortem samples of living or recently extinct species, on the
Brain morphometry - Wikipedia, the free encyclopedia Post-mortem samples of living or recently extinct species, on the other hand, generally allow to obtain MR image qualities sufficient for morphometric ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
other hand, generally allow to obtain MR image qualities sufficient
Brain morphometry - Wikipedia, the free encyclopedia Post-mortem samples of living or recently extinct species, on the other hand, generally allow to obtain MR image qualities sufficient for morphometric ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
for morphometric analyses, though preservation artifacts would have to be
Brain morphometry - Wikipedia, the free encyclopedia ... generally allow to obtain MR image qualities sufficient for morphometric analyses, though preservation artifacts would have to be taken into account. ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
Previous MR imaging studies include specimens preserved in formalin (Pfefferbaum et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Previous MR imaging studies include specimens preserved in formalin (Pfefferbaum et al., 2004 ; Hakeem et al., 2005 , human and elephant ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
, human and elephant brains), by freezing (Corfield et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... 2005 , human and elephant brains), by freezing (Corfield et al., 2008 , kiwi brains) or in alcohol (Chanet et al., 2009 , carps). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
The third line of comparative evidence would be cross-species in
Brain morphometry - Wikipedia, the free encyclopedia The third line of comparative evidence would be cross-species in vivo MR imaging studies like the one by Rilling & Insel (1998) who investigated brains from ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
vivo MR imaging studies like the one by Rilling and
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... The third line of comparative evidence would be cross-species in vivo MR imaging studies like the one by Rilling and Insel (1998, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
, this is the first in a series of papers)
Transport - Transport Papers Series This is the first in a series of papers addressing transit for landlocked countries. TP-12: Maternal and Child Mortality Development Goals: What Can the ... http://web.worldbank.org/WBSITE/EXTERNAL/TOPICS/EX... > Cached
who investigated brains from 11 primate species by VBM in
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... in a series of papers) who investigated brains from 11 primate species by VBM in order to shed new light on primate brain evolution. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Other studies have combined morphometric with behavioural measures (social uprearing in monkeys, Sanchez et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Other studies have combined morphometric with behavioural measures (social uprearing in monkeys, Sanchez et al., 1998 ), and brain evolution ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
), and brain evolution does not only concern primates: Gyrification
Brain morphometry - Wikipedia, the free encyclopedia Other studies have combined morphometric with behavioural measures, and brain evolution does not only concern primates: Gyrification occurs across mammalian ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
occurs across mammalian brains if they reach a size of
Brain morphometry - Wikipedia, the free encyclopedia ... and brain evolution does not only concern primates: Gyrification occurs across mammalian brains if they reach a size of several centimeters—with ... http://en.wikipedia.org/wiki/Brain_morphometry > Cached
and generally increases slowly with overall brain size, following a power law (Hofman, 1989
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... dominating the upper end of the spectrum – and generally increases slowly with overall brain size, following a power law (Hofman, 1989). ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Finally, since many biological mechanisms behind development, aging, learning and
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Finally, since many biological mechanisms behind development, aging, learning and disease are shared between a wide range of organisms (for ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
disease are shared between a wide range of organisms (for
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Finally, since many biological mechanisms behind development, aging, learning and disease are shared between a wide range of organisms (for ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
), evolutionary studies can feed back on clinical ones through model organisms
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... see Carroll, 2005 ), evolutionary studies can feed back on clinical ones through model organisms (see Discussion below). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Given that in vivo MR images have been acquired from the brains of many different species –
In Vivo Structural Brain Assessment Given the complexity and individual variability of each brain, issues of reliability .... New capabilities for 3D display of brain images have greatly expanded options for .... Several different approaches to image acquisition to facilitate subsequent matching of acquired PET and MR images have been developed . ... http://www.acnp.org/g4/GN401000089/CH.html > Cached
the major barrier to cross-species MR-based brain morphometry is not
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... 2009) and even insects (Null et al., 2008) – the major barrier to cross- species MR-based brain morphometry is not the lack of data nor ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
the lack of data nor analytical tools but barriers preventing
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... to cross-species MR-based brain morphometry is not the lack of data nor analytical tools but barriers preventing to combine them. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Some exceptions already exist, though: Rilling and Insel
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Some exceptions already exist, though: Rilling and Insel (1998) , for instance, have shared their dataset 10 , and a number of multicenter ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
, and a number of multicenter initiatives have been set up for that same purpose
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... for instance, have shared their dataset 10 , and a number of multicenter initiatives have been set up for that same purpose. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Amongst the many open research questions pertaining to MR-based brain
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Amongst the many open research questions pertaining to MR-based brain morphometry, we have selected four, progress in which we expect to ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
morphometry, we have selected four, progress in which we expect
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Amongst the many open research questions pertaining to MR-based brain morphometry, we have selected four, progress in which we expect to ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
The relationship between different morphometric measures across time scales or
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... The relationship between different morphometric measures across time scales or brain populations has not received much attention so far, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
brain populations has not received much attention so far, partly
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... scales or brain populations has not received much attention so far, partly because the focus of most studies was on group differences, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
because the focus of most studies was on group differences,
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... attention so far, partly because the focus of most studies was on group differences, for which simply the most suited measure was used. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
A profound understanding of brain structure and its changes, however,
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... A profound understanding of brain structure and its changes, however, has to systematically seek answers to questions like the following: ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
has to systematically seek answers to questions like the following:
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... A profound understanding of brain structure and its changes, however, has to systematically seek answers to questions like the following: ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
brain size according to power laws, what does this mean
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... 2005 ) to increase with a species' brain size according to power laws, what does this mean for the relationship between gyrification and ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
for the relationship between gyrification and cortical thickness within a
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... size according to power laws, what does this mean for the relationship between gyrification and cortical thickness within a species? ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Toro and Burnod, 2005
Brain Size and Folding of the Human Cerebral Cortex — Cereb Cortex Feb 10, 2008 ... 1999; Chenn and Walsh 2002) and put forward theoretically as a major cause of cortical folding (Toro and Burnod 2005). ... http://cercor.oxfordjournals.org/content/18/10/235... > Cached
Many details of the interaction between brain structure and function remain to be understood (Casey et al
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Many details of the interaction between brain structure and function remain to be understood (Casey et al., 2000) but it is clear that most ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
) but it is clear that most of it takes place at the cellular level
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... 2000 ) but it is clear that most of it takes place at the cellular level. Synaptic activity, for instance, controls both the remodeling ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Synaptic activity, for instance, controls both the remodeling of axons (Saxena and Caroni, 2007
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Synaptic activity, for instance, controls both the remodeling of axons (Saxena and Caroni, 2007) and dendritic spines (Bloodgood and ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
) but is mediated by glia cells which, in turn
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... 2007) and dendritic spines (Bloodgood and Sabatini, 2007) but is mediated by glia cells which, in turn guided by synaptic activity, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
guided by synaptic activity, control myelination and vascularization (Haydon and
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... in turn guided by synaptic activity, control myelination and vascularization (Haydon and Carmignoto, 2006 ). A single voxel in brain ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
A single voxel in brain morphometric MR images usually contains
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... A single voxel in brain morphometric MR images usually contains large numbers of such cellular interaction sites and can thus at present not ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
large numbers of such cellular interaction sites and can thus
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... A single voxel in brain morphometric MR images usually contains large numbers of such cellular interaction sites and can thus at present not ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Spatial and temporal resolution in MR imaging can be traded
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Spatial and temporal resolution in MR imaging can be traded for each other and for gains and losses in a number of other parameters over ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
for each other and for gains and losses in a
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Spatial and temporal resolution in MR imaging can be traded for each other and for gains and losses in a number of other parameters over ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
number of other parameters over several orders of magnitude, so
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... for each other and for gains and losses in a number of other parameters over several orders of magnitude, so most resolution limits will ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
most resolution limits will be soft and lend themselves to
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... so most resolution limits will be soft and lend themselves to further technological developments, e.g. in terms of the strength and ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
in terms of the strength and homogeneity of the applied
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... e.g. in terms of the strength and homogeneity of the applied fields, the arrangement of the coils, or the pulse sequences (Blamire, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
fields, the arrangement of the coils, or the pulse sequences
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... e.g. in terms of the strength and homogeneity of the applied fields, the arrangement of the coils, or the pulse sequences (Blamire, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
) and application of contrast agents allowed to reach that level also in the mouse brain (Heyn et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... 2007 ) and application of contrast agents allowed to reach that level also in the mouse brain (Heyn et al., 2006 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Other, and much less negotiable, limits have to be kept in mind, however
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Other, and much less negotiable, limits have to be kept in mind, however. These include the comfort of the subjects – they (patients and ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
These include the comfort of the subjects –
Thoughts on: Moving beyond instructional comfort zones with online ... Aug 17, 2007 ... The specification needs to include some form of capability or performance and ... These assessments are characterised by meaningful and authentic ... of this problem based learning approach in their subject area if they ... http://elearningnews.edublogs.org/2007/08/17/thoug... > Cached
they will rarely be available for scan sessions of an hour or more –
24 Hour Fitness - Hollywood - Los Angeles, CA I haven't experienced a single broken machine, my session with the trainer Chris was great, and they've got ... They will not honor them. Probably not even in writing. ... It's called 24Hr Fitness but this branch closes at 11PM on… Read more » .... Group X: Body Pump is decent but the class rarely starts on time. ... http://www.yelp.com/biz/24-hour-fitness-los-angele... > Cached
and their safety: MR spectroscopy has been performed in static fields of up to 45 T (Gan et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... for scan sessions of an hour or more – and their safety: MR spectroscopy has been performed in static fields of up to 45 T (Gan et al., ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
), but MR imaging of humans at that field strength
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... 2008), but MR imaging of humans at that field strength would be prohibitive because the blood flow-induced current density at the ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
would be prohibitive because the blood flow-induced current density at
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... but MR imaging of humans at that field strength would be prohibitive because the blood flow-induced current density at the cardiac ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
the cardiac pacemaker then approaches the threshold for causing arrhythmia
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... current density at the cardiac pacemaker then approaches the threshold for causing arrhythmia (for review, see Schenck, 2005 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
their specialized brain architecture because of their profession or whether
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... mathematicians) have their specialized brain architecture because of their profession or whether their brain structure predisposed them ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
their brain structure predisposed them to this decision, MR-based morphometric
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... of their profession or whether their brain structure predisposed them to this decision, MR-based morphometric approaches will thus have ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
approaches will thus have to be integrated with results obtained
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... MR-based morphometric approaches will thus have to be integrated with results obtained by complementary methodologies. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
There are ethical and practical limits to investigations of human brains, be they healthy or not
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... There are ethical and practical limits to investigations of human brains, be they healthy or not. While rare clinical cases like that of the ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
a patient who became amnesic after bilateral removal of major parts of his hippocampus
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... Molaison (better known as H. M. – a patient who became amnesic after bilateral removal of major parts of his hippocampus; Salat et al., ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
) may provide for significant advances in a whole field
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... 2006) may provide for significant advances in a whole field of inquiry (in this case memory research), systematic experimentation is ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
and functional aspects of these processes in the intact or
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... provide important insights into structural and functional aspects of these processes in the intact or malfunctioning human brain – e.g. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
and this is a very active field of research (for an overview, see Dijkhuizen and Nicolay, 2003
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... 2007) – and this is a very active field of research (for an overview, see Dijkhuizen and Nicolay, 2003; Beuf et al., 2006). ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Neuroimaging research is currently experiencing a transition to high-throughput data
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Neuroimaging research is currently experiencing a transition to high-throughput data generation that previously led a number of other fields ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
generation that previously led a number of other fields to
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... a transition to high-throughput data generation that previously led a number of other fields to adopt a culture in which data, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
adopt a culture in which data, tools and computational models
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... led a number of other fields to adopt a culture in which data, tools and computational models are shared (Marcus et al., 2007 ). ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Once the data, tools and models are accessible to every researcher, new kinds of research become possible
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... The brain, like any living tissue, is constantly changing in response to genetic and environmental cues and their interaction, ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Looking backward, legacy neuroimaging data can be combined with new
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Looking backward, legacy neuroimaging data can be combined with new analytical tools to provide insights that would not have been possible ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
analytical tools to provide insights that would not have been
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Looking backward, legacy neuroimaging data can be combined with new analytical tools to provide insights that would not have been possible ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
), and existing data from different scanners can be pooled to reach higher statistical power (Moorhead et al
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... 2006 ), and existing data from different scanners can be pooled to reach higher statistical power (Moorhead et al., 2009 ; Segall et al. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
Looking forward, existing tools and platforms allow to extend the
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Looking forward, existing tools and platforms allow to extend the data sharing practice to presenting public data interactively (Shotton et ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
data sharing practice to presenting public data interactively (Shotton et
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... Looking forward, existing tools and platforms allow to extend the data sharing practice to presenting public data interactively (Shotton et ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
), and to embed the results of these activities into
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... to collaborative problem-solving (Nielsen, 2009 ), and to embed the results of these activities into a hyperlinked contextual framework ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
a hyperlinked contextual framework of structured knowledge that can be
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... and to embed the results of these activities into a hyperlinked contextual framework of structured knowledge that can be continuously ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
continuously updated and expanded, as examplified by the fledgling scholarly
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... that can be continuously updated and expanded, as examplified by the fledgling scholarly wikis Scholarpedia16 and Citizendium17, ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
As an experiment to test the potential of such collaborative
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... As an experiment to test the potential of such collaborative environments, we have drafted parts of this manuscript directly in the “Brain ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
environments, we have drafted parts of this manuscript directly in
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... As an experiment to test the potential of such collaborative environments, we have drafted parts of this manuscript directly in the “Brain ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
entries at Citizendium
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011... we have drafted parts of this manuscript directly in the “Brain morphometry” and “Gyrification” entries at Citizendium. ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
If you take a look at these and related wiki
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... If you take a look at these and related wiki entries and start to improve them, this would be a new experience of knowledge sharing for all ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
entries and start to improve them, this would be a
Frontiers | Computational morphometry for detecting changes in ... Mar 4, 2011 ... If you take a look at these and related wiki entries and start to improve them, this would be a new experience of knowledge sharing for all ... http://www.frontiersin.org/neuroinformatics/10.338... > Cached
new experience of knowledge sharing for all of us, and
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009... start to improve them, this would be a new experience of knowledge sharing for all of us, and we are very much looking forward to it. ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
MR-based brain morphometry is currently in a phase of fast development and diversification
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... MR-based brain morphometry is currently in a phase of fast development and diversification. Specifically, brain morphometric approaches ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
Specifically, brain morphometric approaches based on structural MR images allow
Computational Morphometry for Detecting Changes in Brain Structure ... Aug 11, 2009 ... Specifically, brain morphometric approaches based on structural MR images allow to quantify changes in cortical gray matter across both ... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC272966... > Cached
to quantify changes in cortical gray matter across both broad
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models can be expected to lead to considerable progress in
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Thomas Weiss for providing the data underlying Figure 4
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This work was supported in part by BMBF grants 01EV0709 and 01GW0740
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