User:Etienne Robillard/Notebook/chim trills notebook

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23 September 2016

       06:08 User:Etienne Robillard/Notebook/chim trills notebook (diff; hist) . .  (+10) . . Etienne Robillard (Talk | contribs) (Hypothesis: )

19 September 2016

+      10:10 User:Etienne Robillard/Notebook/chim trills notebook‎ (2 changes) . . (+147) . . (Page history) [Etienne Robillard‎ (2×)]

18 September 2016

+      07:08 User:Etienne Robillard/Notebook/chim trills notebook/Research‎ (2 changes) . . (+32) . . (Page history) [Etienne Robillard‎ (2×)]

Contents


Hypothesis

1. The biological impacts of aerosolized nanoparticles (ANP) are poorly understood.

2. The cytotoxicity of nanoparticle-based stratospheric aerosol injection on human health require further investigations.

3. The differential effects of highly dispersed aerosols (HDA) on the neuroimmune system, lung function, chronic inflammation, and Alzheimer pathogenesis requires additional research. [1]

4. Microglial activation is implicated in the aluminium-induced neurotoxicity of aerosolized nanoparticles.

Clinical effects of clandestine geoengineering activity

Cardiovascular system

  • Effects of particulate matter (PM2.5) air pollution on cardiovascular disease [2]
    • Increase in blood pressure [3]

Respiratory system

  • AECOPD [4]
  • Lung cancer [5]

Brain/CNS

  • Alzheimer [6]
  • PM2.5 exposure may cause neuroinflammation and oxidative stress. [4][7][8][9]
    • PM2.5 exposure induce selective neurotoxicity through glutamatergic signaling and increase NMDA-induced excitotoxicity. [7][10]
  • Dopaminergic/serotonergic signaling upregulation?

Lymphatic system

  • Lipid peroxidation and oxidative DNA damage. [11]

Cognitive infiltration evidences

Notes

Resources

Keywords

aerosol, bioaerosol, nanoparticles, aluminium oxide, particulate matter, PM2.5, aerosolized jet fuel, gulf war syndrome, chronic neuroinflammation, vapor phase oxidation, hydrocarbons, barium hexaaluminate

Support this project

This project is entirely financed by personal donations. To support this project, use the following link to donate money via Paypal: https://paypal.me/EtienneRobillard

References

  1. Gilmour MI, O'Connor S, Dick CA, Miller CA, and Linak WP. . pmid:15061611. PubMed HubMed [Gilmour-2004]
    Differential pulmonary inflammation and in vitro cytotoxicity of size-fractionated fly ash particles from pulverized coal combustion.

  2. Brook RD, Rajagopalan S, Pope CA 3rd, Brook JR, Bhatnagar A, Diez-Roux AV, Holguin F, Hong Y, Luepker RV, Mittleman MA, Peters A, Siscovick D, Smith SC Jr, Whitsel L, Kaufman JD, and American Heart Association Council on Epidemiology and Prevention, Council on the Kidney in Cardiovascular Disease, and Council on Nutrition, Physical Activity and Metabolism. . pmid:20458016. PubMed HubMed [Brook-2010]
    Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association.

  3. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402685/

    [Balasubramanian-2013]

    Differential effects of inhalation exposure to PM2.5 on hypothalamic monoamines and corticotrophin releasing hormone in lean and obese rats.

  4. http://journal.frontiersin.org/article/10.3389/fphys.2015.00294/full

    [Lei-2015]

    Fine particulate matter in acute exacerbation of COPD.

  5. Hamra GB, Guha N, Cohen A, Laden F, Raaschou-Nielsen O, Samet JM, Vineis P, Forastiere F, Saldiva P, Yorifuji T, and Loomis D. . pmid:24911630. PubMed HubMed [Hamra-2014]
    Outdoor particulate matter exposure and lung cancer: a systematic review and meta-analysis.

  6. Jung CR, Lin YT, and Hwang BF. . pmid:25310992. PubMed HubMed [Jung-2015]
    Ozone, particulate matter, and newly diagnosed Alzheimer's disease: a population-based cohort study in Taiwan.

  7. Liu F, Huang Y, Zhang F, Chen Q, Wu B, Rui W, Zheng JC, and Ding W. . pmid:25913161. PubMed HubMed [Liu-2015]
    Macrophages treated with particulate matter PM2.5 induce selective neurotoxicity through glutaminase-mediated glutamate generation.

  8. Riva DR, Magalhães CB, Lopes AA, Lanças T, Mauad T, Malm O, Valença SS, Saldiva PH, Faffe DS, and Zin WA. . pmid:21506876. PubMed HubMed [Riva-2011]
    Low dose of fine particulate matter (PM2.5) can induce acute oxidative stress, inflammation and pulmonary impairment in healthy mice.

  9. Levesque S, Taetzsch T, Lull ME, Kodavanti U, Stadler K, Wagner A, Johnson JA, Duke L, Kodavanti P, Surace MJ, and Block ML. . pmid:21561831. PubMed HubMed [Levesque-2011]
    Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity.

  10. Morgan TE, Davis DA, Iwata N, Tanner JA, Snyder D, Ning Z, Kam W, Hsu YT, Winkler JW, Chen JC, Petasis NA, Baudry M, Sioutas C, and Finch CE. . pmid:21724521. PubMed HubMed [Morgan-2011]
    Glutamatergic neurons in rodent models respond to nanoscale particulate urban air pollutants in vivo and in vitro.

  11. Ambroz A, Vlkova V, Rossner P Jr, Rossnerova A, Svecova V, Milcova A, Pulkrabova J, Hajslova J, Veleminsky M Jr, Solansky I, and Sram RJ. . pmid:27321041. PubMed HubMed [Ambroz-2016]
    Impact of air pollution on oxidative DNA damage and lipid peroxidation in mothers and their newborns.

  12. http://www.mdpi.com/1660-4601/12/8/9375/htm

    [Herndon-2015]

    Evidence of Coal-Fly-Ash Toxic Chemical Geoengineering in the Troposphere: Consequences for Public Health

  13. http://nuclearplanet.com/frontiers1.pdf

    [Herndon-2016]

    Human and Environmental Dangers Posed by Ongoing Global Tropospheric Aerosolized Particulates for Weather Modification.

  14. http://www.tandfonline.com/doi/abs/10.1080/027868201753306714

    [Cheng-2010]

    Chemical Composition of Aerosols from Kerosene Heaters Burning Jet Fuels.

All Medline abstracts: PubMed HubMed

License

Copyright (C) 2012-2016 Etienne Robillard

Permission is granted to copy, distribute and/or modify this document Under the terms of the GNU Free Documentation License, Version 1.3 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled "GNU Free Documentation License".



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