Kevin G. Hoff
Department of Chemistry and Chemical Engineering
1200 E. California Blvd. MC 210-41
California Institute of Technology
Pasadena, CA 91125
khoff at caltech dot edu
I am a member of the Smolke Lab at Caltech. My research is directed toward developing in vivo biosensors with the ability to detect fluctuations in metabolite and protein concentrations as well as post-translational modifications.
My background is in the study of protein structure-function relationships. Through this work I have become interested in the changes in protein modifications and metabolite flux that occur during the cell cycle. I am particularly interested in the way post-translational modifications and small molecules influence epigenetic control of transcription.
- 2005-present Postdoctoral Scholar, Laboratory of Dr. Christina D. Smolke, Caltech
- 2002-2005 HHMI Post-Doctoral Fellow, Laboratory of Dr. Cynthia Wolberger, The Johns Hopkins School of Medicine.
- 2002 Ph.D. Biophysics, Laboratory of Dr. Larry E. Vickery, University of California, Irvine.
- 1996 B. A. Biology/Chemistry Minor, California State University, Fullerton
- Hoff KG, Goodlitt R, Li R, Smolke CD, and Silberg JJ. . pmid:19184988.
- Bayer TS, Hoff KG, Beisel CL, Lee JJ, and Smolke CD. . pmid:19118500.
- Beisel CL, Bayer TS, Hoff KG, and Smolke CD. . pmid:18956013.
- Hawse WF, Hoff KG, Fatkins DG, Daines A, Zubkova OV, Schramm VL, Zheng W, and Wolberger C. . pmid:18786399.
- Hoff KG, Avalos JL, Sens K, and Wolberger C. . pmid:16905097.
- Previewed in Smith BC and Denu JM. Sirtuins caught in the act. Structure. 2006 Aug;14(8):1207-8.
- Hoff KG and Wolberger C. . pmid:15999106.
- Silberg JJ, Tapley TL, Hoff KG, and Vickery LE. . pmid:15485839.
- Hoff KG, Cupp-Vickery JR, and Vickery LE. . pmid:12871959.
- Hoff KG, Ta DT, Tapley TL, Silberg JJ, and Vickery LE. . pmid:11994302.
- Urbina HD, Silberg JJ, Hoff KG, and Vickery LE. . pmid:11577100.
- Voisine C, Cheng YC, Ohlson M, Schilke B, Hoff K, Beinert H, Marszalek J, and Craig EA. . pmid:11171977.
- Silberg JJ, Hoff KG, Tapley TL, and Vickery LE. . pmid:11053447.
- Hoff KG, Silberg JJ, and Vickery LE. . pmid:10869428.
- Garland SA, Hoff K, Vickery LE, and Culotta VC. . pmid:10588895.
- Silberg JJ, Hoff KG, and Vickery LE. . pmid:9852006.
Protocols and Recipes
Recipes and other stuff