From OpenWetWare

Jump to: navigation, search

Home        Contact        Internal        Protocols        Lab Members        Publications        Research       

Kevin G. Hoff

Department of Chemistry and Chemical Engineering
1200 E. California Blvd. MC 210-41
California Institute of Technology
Pasadena, CA 91125

khoff at caltech dot edu

I am a member of the Smolke Lab at Caltech. My research is directed toward developing in vivo biosensors with the ability to detect fluctuations in metabolite and protein concentrations as well as post-translational modifications.


Research Interests

My background is in the study of protein structure-function relationships. Through this work I have become interested in the changes in protein modifications and metabolite flux that occur during the cell cycle. I am particularly interested in the way post-translational modifications and small molecules influence epigenetic control of transcription.


  • 2005-present Postdoctoral Scholar, Laboratory of Dr. Christina D. Smolke, Caltech
  • 2002-2005 HHMI Post-Doctoral Fellow, Laboratory of Dr. Cynthia Wolberger, The Johns Hopkins School of Medicine.
  • 2002 Ph.D. Biophysics, Laboratory of Dr. Larry E. Vickery, University of California, Irvine.
  • 1996 B. A. Biology/Chemistry Minor, California State University, Fullerton


  1. Hoff KG, Goodlitt R, Li R, Smolke CD, and Silberg JJ. . pmid:19184988. PubMed HubMed [hoff15]
  2. Bayer TS, Hoff KG, Beisel CL, Lee JJ, and Smolke CD. . pmid:19118500. PubMed HubMed [hoff14]
  3. Beisel CL, Bayer TS, Hoff KG, and Smolke CD. . pmid:18956013. PubMed HubMed [hoff13]
  4. Hawse WF, Hoff KG, Fatkins DG, Daines A, Zubkova OV, Schramm VL, Zheng W, and Wolberger C. . pmid:18786399. PubMed HubMed [hoff12]
  5. Hoff KG, Avalos JL, Sens K, and Wolberger C. . pmid:16905097. PubMed HubMed [hoff11]
All Medline abstracts: PubMed HubMed
  • Previewed in Smith BC and Denu JM. Sirtuins caught in the act. Structure. 2006 Aug;14(8):1207-8.
  1. Hoff KG and Wolberger C. . pmid:15999106. PubMed HubMed [hoff1]
  2. Silberg JJ, Tapley TL, Hoff KG, and Vickery LE. . pmid:15485839. PubMed HubMed [hoff2]
  3. Hoff KG, Cupp-Vickery JR, and Vickery LE. . pmid:12871959. PubMed HubMed [hoff3]
  4. Hoff KG, Ta DT, Tapley TL, Silberg JJ, and Vickery LE. . pmid:11994302. PubMed HubMed [hoff4]
  5. Urbina HD, Silberg JJ, Hoff KG, and Vickery LE. . pmid:11577100. PubMed HubMed [hoff5]
  6. Voisine C, Cheng YC, Ohlson M, Schilke B, Hoff K, Beinert H, Marszalek J, and Craig EA. . pmid:11171977. PubMed HubMed [hoff6]
  7. Silberg JJ, Hoff KG, Tapley TL, and Vickery LE. . pmid:11053447. PubMed HubMed [hoff7]
  8. Hoff KG, Silberg JJ, and Vickery LE. . pmid:10869428. PubMed HubMed [hoff8]
  9. Garland SA, Hoff K, Vickery LE, and Culotta VC. . pmid:10588895. PubMed HubMed [hoff9]
  10. Silberg JJ, Hoff KG, and Vickery LE. . pmid:9852006. PubMed HubMed [hoff10]
All Medline abstracts: PubMed HubMed

Protocols and Recipes


Recipes and other stuff

Personal tools