- Georgia Institute of Technology
- Wallace H. Coulter Department of Biomedical Engineering
- Emory + Georgia Tech Center for Pediatric Nanomedicine (CPN)
- Children's Heart Research and Outcomes (HeRO)
- B.Sc. Biology, Georgia Institute of Technology
- Modeling pediatric cardiac diseases using patient-specific hiPSC-derived cardiomyocytes. Primary models in development include: Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) and Duchenne Muscular Dystrophy (DMD).
- Investigating the use of the CRISPR/Cas9 gene-editing system to correct disease-causing mutations in human pluripotent stem cells.
- Exploring the functional consequences of microgravity on human cardiac development, with implications for future space-colonization.
- Microscale Generation of Cardiospheres Promotes Robust Enrichment of Cardiomyocytes Derived from Human Pluripotent Stem Cells
Generation of cardiospheres represents a simple and robust method for enrichment of cardiomyocytes in microtissues that have the potential use in regenerative medicine as well as other applications.
- Blood-Informative Transcripts Define Nine Common Axes of Peripheral Blood Gene Expression
We describe a novel approach to capturing the covariance structure of peripheral blood gene expression that relies on the identification of highly conserved Axes of variation.