User:Marcela Preininger

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Contact Info

Marcela Preininger (an artistic interpretation)
Marcela Preininger (an artistic interpretation)

mpreininger@gmail.com

Affiliations:

  1. Georgia Institute of Technology
  2. Wallace H. Coulter Department of Biomedical Engineering
  3. Emory + Georgia Tech Center for Pediatric Nanomedicine (CPN)
  4. Children's Heart Research and Outcomes (HeRO)

Education

  • B.Sc. Biology, Georgia Institute of Technology

Research interests

  1. Modeling pediatric cardiac diseases using patient-specific hiPSC-derived cardiomyocytes. Primary models in development include: Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) and Duchenne Muscular Dystrophy (DMD).
  2. Investigating the use of the CRISPR/Cas9 gene-editing system to correct disease-causing mutations in human pluripotent stem cells.
  3. Exploring the functional consequences of microgravity on human cardiac development, with implications for future space-colonization.

Publications

  1. Microscale Generation of Cardiospheres Promotes Robust Enrichment of Cardiomyocytes Derived from Human Pluripotent Stem Cells [25254340]
    Generation of cardiospheres represents a simple and robust method for enrichment of cardiomyocytes in microtissues that have the potential use in regenerative medicine as well as other applications.

  2. Blood-Informative Transcripts Define Nine Common Axes of Peripheral Blood Gene Expression

    [23516379]

    We describe a novel approach to capturing the covariance structure of peripheral blood gene expression that relies on the identification of highly conserved Axes of variation.

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