User:Mbennie/Notebook/Papers and Books/Applications

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Error fetching PMID 16330045:
  1. Error fetching PMID 16330045: [Controlled-Invasion]
  • Used invasin to target tumor cells using factors such as hypoxia and bacteria's natural tendency to grow in regions of high cell density
  • Mammalian cells normally take up a cell with invasin
  • Used directed evolution to find strains that worked according to their parameters: invasion under certain condition and no invasion otherwise

Error fetching PMID 8598934:
  1. Error fetching PMID 8598934: [Organ-targeting]
  • Isolated phage that were targeted towards specific organs by repeated injection and recovery
  • Found phage that were 8 times more targeted towards the kidneys or brain

Error fetching PMID 11545269:
  1. Error fetching PMID 11545269: [Cols-Secretion]
  • Attempts to express MT in e coli and secreted into media in order to bind Cu
  • MT is a really cool protein (binds several types of heavy metals)
  • Hypothesized that metal binds to MT inside of cell, but in periplasm metal release when disulfide bridge is formed
  • Removed 34% of Cu using best plasmid
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