User:Sean D Colloms

Contact Info

Sean D Colloms

• Sean D Colloms
• University of Glasgow
• Bower Building
• University Ave
• Glasgow, G12 8QQ, Scotland, UK.
• Email me through OpenWetWare

Education

• 1991, PhD, University of Glasgow
• 1987, BA, University of Cambridge

Research interests

1. My lab at the University of Glasgow works on DNA transposition and site-specific recombination. These are DNA rearrangements that are catalysed by specific enzymes (transposases and site-specific recombinases) that recognise short DNA sequences, cleave the DNA backbone at these sequences, and then rejoin them in new configurations.

• We are interested in the mechanism of site-specific recombination and transposition, and also their applications for Synthetic biology.

• Together with William Brown (University of Nottingham), Oliver Ebenhoeh (University of Aberdeen / Heinrich Heine University Düsseldorf), Susan Rosser (University of Edinburgh), Maggie Smith (University of Nottingham), Marshall Stark (University of Glasgow), I have a BBSRC strategic longer and larger grant to develop large serine recombinases for Synthetic Biology and Biotechnology http://www.bbsrc.ac.uk/pa/grants/AwardDetails.aspx?FundingReference=BB/K003356/1.

We refer to this technology as SIDR for Serine Integrase Directional Recombination. The specific use of SIDR for gene assembly is referred to as Serine Integrase Recombinational Assembly SIRA

Publications

<biblio>

1. Paper pmid=24225316

// leave a comment about a paper here

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