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<div id="mainpage">
<hr class=divider>
<div id="about">
{| align="right"
| Welcome to Harvard's 2006 '''iGEM''' team wiki! Please click on the project of interest for up to date information and current progress.
| [[Image:Igem2006logo.gif|40px]]
|}
</div><br><br>
<hr class=divider>
{| cellspacing="5"
|width="280px" bgcolor="#DDDDFF" |
<!-- COMMUNITY HEADER with edit link-->
<h3><html>
<img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources">
</html>Planning</h3>
<hr/>
<!-- END COMMUNITY HEADER-->
===News and Announcements===
*[http://fontana.med.harvard.edu/stroustr/igem/ Jamboree Photos]
*[[/Final Presentation|Final Presentation]]
===Team===
*[[/Background Reading/]]
*[[/Meetings/]]
*[[/Lab Intro/|Lab schedule]]
*[[/Personnel Schedule/|Personnel schedule]]
===Projects===
*[[/Cyanobacteria/]]
**[[/Cyanobacteria/Notebook|Notebook]]
*[[/Cell surface targeting|Cell Surface Targeting]]
**[[/Adaptamers/|Adaptamers]]
**[[/Fusion proteins/|Streptavidin Cell Surface Fusion Protein]]
*[[/DNA nanostructures/]]
**[[/DNA_nanostructures/Notebook|Notebook]]
===Project Planning===
*[[/Brainstorming/]]
*[[Past project presentation sign ups|Sign up]]
*[[Past project notes]]
===For visitors===
*[http://www.technologyreview.com/BioTech/17790/ Weaving Barrels from DNA] <small>(11/15/06)</small>
*[http://parts.mit.edu/wiki/index.php/Harvard_2006 Official 2006 Harvard iGEM team page]
*[[Synthetic Biology]]
*[http://parts2.mit.edu/wiki/index.php/Main_Page Official iGEM page]
*[http://parts2.mit.edu/wiki/index.php/Schools_Participating_in_iGEM_2006 Participating Institutions]
*[http://karma.med.harvard.edu/wiki/IGEM_2005 2005 Harvard iGEM wiki]
*[http://www.nature.com/nature/comics/syntheticbiologycomic/ SynBio Comic]
*[http://karma.med.harvard.edu/w/images/7/7c/Igem05-nyt-article.pdf NYT article] <small>(11/24/05)</small>
|width="230px" bgcolor="#EEEEEE" |
<!-- NEWS HEADER with edit link-->
<h3><html>
<img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="News" border="0">
</html>In the Lab</h3>
<hr/>
<!-- END NEWS HEADER with edit link-->
===Protocols===
*[[Protocols | Open Wetware Protocols]]
**[[DNA_Ligation | Ligation Protocol]]
*[[IGEM:Harvard/2006/Protocols | Our Own Protocols]]
===Lab Notebooks===
*[[IGEM:Harvard/2006/Laboratory_Notebooks | Laboratory Notebooks]]
===Useful links===
iGEM and OWW
*[[Etiquette|OpenWetWare Etiquette]]
*[[IGEM|Other iGEM teams on OWW]]
*[http://parts.mit.edu/registry BioBricks registry]
*[http://parts.mit.edu/wiki/index.php/Harvard_2006 Harvard page on iGEM wiki]
Literature
*[http://nrs.harvard.edu/urn-3:hul.eresource:pubmedpi Pubmed for Harvard PIN holders]
*[http://portal.isiknowledge.com.ezp1.harvard.edu ISI Web of Science]
Python
*[http://diveintopython.org/toc/index.html Dive Into Python]
*[http://docs.python.org/tut/tut.html Python Tutorial]
*[http://wiki.python.org/moin/PerlPhrasebook Perl to Python]
*[http://www.python.org/doc/2.4.1/lib/lib.html Python Lib Ref]
*[http://www.amk.ca/python/howto/regex/ Py Reg Ex]
Miscellaneous
*[http://people.fas.harvard.edu/~sdouglas/table.cgi Excel &rarr; Wiki Table converter]
*[[IGEM:Harvard/2006/Presentation Advice | Presentation Advice]]
*[[Kafatos:DNA_1kbplus_ladder | 1 kb+ ladder]]
*[http://www.epibio.com/techapp.asp Buffer and gel tables]
*[http://www.promega.com/biomath/default.htm BioMath calculators (Promega)]
|width="200px" bgcolor="#DDDDFF" |
<!-- PEOPLE HEADER with edit link-->
<h3><html>
<img src="http://openwetware.org/images/3/39/Icon_groups.png" alt="People">
</html>People</h3>
<hr/>
<!-- END PEOPLE HEADER with edit link-->
===[[/Super Heroes|Super Heroes]]===
=====DNA Nanostructures=====
*[[User:TChan|Tiffany Chan]] ([[User_talk:TChan|talk]])
*[[User:Kfifer|Katherine Fifer]] ([[User_talk:Kfifer|talk]])
*[[User:Vlau|Valerie Lau]] ([[User_talk:Vlau|talk]])
*[[User:Matthewmeisel|Matthew Meisel]] ([[User_talk:Matthewmeisel|talk]])
=====Cyanobacteria=====
*[[User:Hetmann|Hetmann Hsieh]] ([[User_talk:Hetmann|talk]])
*[[User:JeffreyLau|Jeffrey Lau]] ([[User_talk:JeffreyLau|talk]])
*[[User:Zhipeng Sun|Zhipeng Sun]] ([[User_talk:Zhipeng_Sun|talk]])
*[[User:DavidRamos|David Ramos]] ([[User_talk:DavidRamos|talk]])
=====Cell surface targeting=====
*[[User:Perry|Perry Tsai]] ([[User_talk:Perry|talk]])
*[[User:Lhahn|Lewis Hahn]] ([[User_talk:Lhahn|talk]])
===Teaching Fellows===
*[[User:doucette|Chris Doucette]] ([[User_talk:Doucette|talk]])
*[[User:ShawnDouglas|Shawn Douglas]] ([[User_talk:ShawnDouglas|talk]])
*[[User:Stroustr|Nicholas Stroustrup]] ([[User_talk:Stroustr|talk]])
===Advisors===
*[[User:PamSilver|Pamela Silver]] ([[User_talk:PamSilver|talk]])
*[[User:Geochurch|George Church]] ([http://arep.med.harvard.edu/gmc/email.html talk])
*[http://www.eecs.harvard.edu/~rad/ Radhika Nagpal]
*[[User:jvshah|Jagesh V. Shah]]
*[[User:wmshih|William Shih]] ([[User_talk:wmshih|talk]])
*Alain Viel
|}
[[Image:Harvard06_iGem.JPG|left|thumb|300px|Harvard 2006 iGem team. <br><br>
'''Back row''' (L-R): [[User:Lhahn|Lewis]], [[User:Kfifer|Katie]], [[User:TChan|Tiffany]], [[User:Vlau|Valerie]], [[User:Zhipeng Sun|Zhipeng]], [[User:Matthewmeisel|Matt]]. <br>
'''Front row''' (L-R): [[User:Hetmann|Hetmann]], [[User:JeffreyLau|Jeffrey]], [[User:DavidRamos|David]], [[User:Perry|Perry]]. <br><br>
And yes, that is the back end of a [http://www.news.harvard.edu/gazette/2003/09.18/28-rhino.html bronze rhinoceros].]]
.
</div>
A thanks goes to [[iGEM:MIT/2006|MIT's team page]] for our page formatting.
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Revision as of 19:15, 25 April 2007


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<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="News" border="100"> </html>NEWS


<html> <img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources"> </html> PLANNING


<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="News" border="0"> </html>WORKSHOP

<html> <img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources"> </html> PROJECT



<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png"> </html> USEFUL LINKS

<html> <img src="http://openwetware.org/images/3/39/Icon_groups.png" alt="People"> </html>PEOPLE

Students


Advisors






Project Overview

  • Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
  • The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
  • As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
  • We expect that molecular containers could have several interesting scientific and clinical applications, such as
    • Drug and gene delivery
    • Bio-marker scavenging (early detection of biomarkers)
    • Directed evolution (compartmentalized selections)
    • Using multiplexing for combinatorial chemical synthesis
    • Capture and stabilization of multiprotein complexes
    • Protein folding (chaperones)
    • Cell sorting

==Working Team Members== edit

Recent Changes

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Welcome to Harvard's 2006 iGEM team wiki! Please click on the project of interest for up to date information and current progress.



<html> <img src="http://openwetware.org/images/b/b9/Icon_board.png" alt="Resources"> </html>Planning


News and Announcements

Team

Projects

Project Planning

For visitors


<html> <img src="http://openwetware.org/images/e/e2/Icon_info.png" alt="News" border="0"> </html>In the Lab


Protocols

Lab Notebooks

Useful links

iGEM and OWW

Literature

Python

Miscellaneous

<html> <img src="http://openwetware.org/images/3/39/Icon_groups.png" alt="People"> </html>People


Super Heroes

DNA Nanostructures
Cyanobacteria
Cell surface targeting

Teaching Fellows

Advisors

Harvard 2006 iGem team.

Back row (L-R): Lewis, Katie, Tiffany, Valerie, Zhipeng, Matt.
Front row (L-R): Hetmann, Jeffrey, David, Perry.

And yes, that is the back end of a bronze rhinoceros.

.

A thanks goes to MIT's team page for our page formatting.