HughesLab:Research

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Discovery of circadian harmonics

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Figure 1: Hughes et al. (2009)
Transcriptional profiling of the mouse liver identified rhythmic transcripts with period lengths of ~8, ~12, and ~24 hours.

System-driven circadian oscillations

Figure 2: Hughes et al. (2012b)
~100 genes oscillate in the mouse liver, despite ablation of the local, peripheral clock.

Rhythms of snoRNA host genes

Figure 3: Hughes et al. (2012a)
Non-coding, snoRNA host genes oscillate in the fly brain

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Hughes Lab
Department of Biology
University of Missouri, St. Louis
(Starting in August, 2013)