User:Liuzhec
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Project Overview
- Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
- The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
- As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
- We expect that molecular containers could have several interesting scientific and clinical applications, such as
- Drug and gene delivery
- Bio-marker scavenging (early detection of biomarkers)
- Directed evolution (compartmentalized selections)
- Using multiplexing for combinatorial chemical synthesis
- Capture and stabilization of multiprotein complexes
- Protein folding (chaperones)
- Cell sorting
==Working Team Members== edit
- Tiffany Chan (talk, edits)
- Katherine Fifer (talk, edits)
- Valerie Lau (talk, edits)
- Matthew Meisel (talk, edits)
- Lewis Hahn (talk, edits)
- TA: Shawn Douglas (talk, edits)
Recent Changes
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2 April 2026
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19:42 David Altman talk contribs uploaded File:Soto WUbites Spring 2026.pdf | ||||
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19:42 David Altman talk contribs uploaded File:Margerum WUbites Spring 2026.pdf | ||||
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19:42 David Altman talk contribs uploaded File:Bentley WUbites Spring 2026.pdf | ||||
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19:40 David Altman talk contribs uploaded File:Bashioum WUbites Spring 2026.pdf | ||||
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09:27 Xinyu Liu talk contribs uploaded File:Small2026.jpg | ||||
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09:28 | Gao lab:Publications 2 changes history +549 [Xinyu Liu (2×)] | |||
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1 April 2026
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11:32 | Hu 2 changes history +121 [Hugangqing (2×)] | |||
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11:32 (cur | prev) +2 Hugangqing talk contribs | ||||
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