Eva Martinez: Difference between revisions
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“Hypoxia alters the adhesive properties of lymphatic endothelial cells. A transcriptional and functional study”. Irigoyen, M., Ansó, E., Martínez, E., Garayoa, M., Martínez-Irujo, JJ. and Rouzaut, A. Biochim Biophys Acta. 2007 Jun;1773(6):880-90 | “Hypoxia alters the adhesive properties of lymphatic endothelial cells. A transcriptional and functional study”. Irigoyen, M., Ansó, E., Martínez, E., Garayoa, M., Martínez-Irujo, JJ. and Rouzaut, A. Biochim Biophys Acta. 2007 Jun;1773(6):880-90 | ||
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Revision as of 12:12, 20 March 2008
'Eva Martinez, PhD'
Posdoctoral Fellow
“Epigenetic Deregulation by The Multiple Myeloma SET Domain Protein”
I obtained my PhD in Cell and Molecular Biology in Biochemistry Department of University of Navarra and in the Tumoral Microenvironmet Laboratory (CIMA). I studied the effects of nicotine in the differentiation of primary human bronchial epithelial cells towards a neuronal-like phenotype. Recently, I moved to Chicago to begin a postdoctoral fellowship in Dr. Licht’s laboratory. Here, I am studying the epigenetic deregulation by MMSET protein. Multiple Myeloma (MM), a neoplasm of plasma cells accounts for up to 10% of hematological malignancies. MMSET was identified at the breakpoint of translocation (4;14) present in 15% of MM. Due to this rearrangement, MMSET level is markedly elevated in t(4;14) myeloma and these patients have a worse prognosis than others.
Publications:
“Recurrent exposure to nicotine differentiates human bronchial epithelial cells via epidermal growth factor receptor activation”. Martínez-García, E. Irigoyen, M., Ansó, E., Martínez-Irujo, JJ. and Rouzaut, A. Toxicology and Applied Pharmacology. 2007 Dec..
“Hypoxia alters the adhesive properties of lymphatic endothelial cells. A transcriptional and functional study”. Irigoyen, M., Ansó, E., Martínez, E., Garayoa, M., Martínez-Irujo, JJ. and Rouzaut, A. Biochim Biophys Acta. 2007 Jun;1773(6):880-90
Back to Jonathan Licht's Lab
