Harvard:Biophysics 242r/2011: Difference between revisions
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==Course overview== | ==Course overview== | ||
*Graduate level seminar focusing on in-silico design pipelines for nucleic acid- and protein-based molecular machinery and programmable molecular systems. Students are mentored to produce substantial midterm and final group design projects. | |||
*No formal prerequisites. Projects are tailored to each student's strengths and interests. | |||
<br> | |||
==Example topics for final design project== | |||
*'''Artificial chemotactic swimmers''' | |||
*'''Nonequilibrium networks of nano-machines mimicking dynamic instability in the cytoskeleton''' | |||
*'''Nucleic acid logic automata responsive to microRNAs in serum''' | |||
*'''Self-assembled solar energy harvester based on bio-inorganic nano-antennae for uv-vis''' | |||
*'''Systematic debugging of DNA labeling chemistries by atomic-resolution TEM imaging of DNA origami''' | |||
*'''Light-controlled transcriptional activation and repression through rational molecular design''' | |||
*'''Directed evolution of tissue engineering scaffold nano-materials''' | |||
*'''Programmable multistep chemical synthesis by templating on nanostructures''' | |||
*'''Ultra-sensitive molecular signal processing for synthetic biology''' | |||
*'''Synthetic nanostructure - virus conjugates''' | |||
*'''Nano-breadboards for probing electron transport in proteins''' | |||
*'''Replication of information in synthetic crystals''' | |||
*'''Etc.''' | |||
<br> | |||
==Logistics== | ==Logistics== | ||
*Meeting time: 2011 Spring Term, Mondays and Wednesdays, | *Meeting time: 2011 Spring Term, Mondays and Wednesdays, 100 pm — 230 pm, with optional sessions for working on projects from 230 pm to 330 pm, starting on Monday, February 7 | ||
*Form teams for midterm projects on Monday, February 7 | |||
*Form teams for final projects on Monday, March 21 | |||
* [http://www.college.harvard.edu/calendar.html First class] on Monday, January 24 | * [http://www.college.harvard.edu/calendar.html First class] on Monday, January 24 | ||
*Location: CLSB521 | *Location: CLSB521 | ||
*No exams | *No exams | ||
*Prerequisites: | *Prerequisites: none | ||
*Grading | *Grading | ||
** | **33% Participation | ||
** | **33% Midterm project | ||
** | **33% Final project | ||
*[http://isites.harvard.edu/icb/icb.do?keyword=k74783&pageid=icb.page.inlinecontent.icb.page375264.icb.page375264 Harvard course site] | |||
*[[Harvard:Biophysics_242r/2011/Course Development Log]]<br> | |||
<br> | <br> | ||
==Background Info and previous class projects== | ==Background Info and previous class projects== | ||
*http://openwetware.org/wiki/Biophysics_242r/2009 | *http://openwetware.org/wiki/Biophysics_242r/2009 | ||
<br> | |||
==Recent changes== | ==Recent changes== |
Latest revision as of 01:28, 13 December 2010
Course overview
- Graduate level seminar focusing on in-silico design pipelines for nucleic acid- and protein-based molecular machinery and programmable molecular systems. Students are mentored to produce substantial midterm and final group design projects.
- No formal prerequisites. Projects are tailored to each student's strengths and interests.
Example topics for final design project
- Artificial chemotactic swimmers
- Nonequilibrium networks of nano-machines mimicking dynamic instability in the cytoskeleton
- Nucleic acid logic automata responsive to microRNAs in serum
- Self-assembled solar energy harvester based on bio-inorganic nano-antennae for uv-vis
- Systematic debugging of DNA labeling chemistries by atomic-resolution TEM imaging of DNA origami
- Light-controlled transcriptional activation and repression through rational molecular design
- Directed evolution of tissue engineering scaffold nano-materials
- Programmable multistep chemical synthesis by templating on nanostructures
- Ultra-sensitive molecular signal processing for synthetic biology
- Synthetic nanostructure - virus conjugates
- Nano-breadboards for probing electron transport in proteins
- Replication of information in synthetic crystals
- Etc.
Logistics
- Meeting time: 2011 Spring Term, Mondays and Wednesdays, 100 pm — 230 pm, with optional sessions for working on projects from 230 pm to 330 pm, starting on Monday, February 7
- Form teams for midterm projects on Monday, February 7
- Form teams for final projects on Monday, March 21
- First class on Monday, January 24
- Location: CLSB521
- No exams
- Prerequisites: none
- Grading
- 33% Participation
- 33% Midterm project
- 33% Final project
- Harvard course site
- Harvard:Biophysics_242r/2011/Course Development Log
Background Info and previous class projects
Recent changes
List of abbreviations:
- N
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