Sarah Carratt 4.14.11

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(New page: ==Overview== *dx/dt = production rate - degradation rate **degradation rate: amount a fraction of material beaks down in each unit time period **production rate: ***model factors: liner, M...)
Current revision (12:52, 14 April 2011) (view source)
(Matrix Games)
 
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==Matrix Games==
==Matrix Games==
*Recall our adjacency matrix A ('''transpose''' of YEASTRACT)
*Recall our adjacency matrix A ('''transpose''' of YEASTRACT)
-
**1 if gene j affects gene i (effectors on side, affectees on top)
+
**1 if gene j affects gene i
**0 if not  
**0 if not  
*there are scaling factors of weights and thresholds
*there are scaling factors of weights and thresholds

Current revision

Overview

  • dx/dt = production rate - degradation rate
    • degradation rate: amount a fraction of material beaks down in each unit time period
    • production rate:
      • model factors: liner, MM, sigmoid (smoothing out of on-off switch)
      • S'(x) = 1/ (1+e-x)
        • S(w(x-t))where w=scaling,t=threshold at on-off junction

Matrix Games

  • Recall our adjacency matrix A (transpose of YEASTRACT)
    • 1 if gene j affects gene i
    • 0 if not
  • there are scaling factors of weights and thresholds
    • affectee receives switching sights from affectors

Difference between "1" and "1"

  • if more turns on and less "turns off"...activation
  • more turns off and less "turns on"...activation
  • switch between by flipping sign on scalar
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