User:Tkadm30/Notebook/Research: Difference between revisions

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=== Cannabimimetic effects of DHA on neurotransmission ===
=== Cannabimimetic effects of DHA on neurotransmission ===
P2X7 receptor mediate DHA signaling and intracellular signal transduction pathways
P2X7 receptor mediate synaptogenic DHA signaling and intracellular signal transduction pathways
relevant to PPAR-induced neural differentiation.
relevant to PPAR-induced neural differentiation.
* [[User:Etienne_Robillard/Notebook/DHA|DHA Notebook]]
* [[User:Etienne_Robillard/Notebook/DHA|DHA Notebook]]

Revision as of 06:51, 13 November 2015

Research Interests

  • Neuroinflammation of the hippocampus/CNS
  • Glutamatergic system/neurotransmission
  • Glutamate neurotoxicity
  • Astrocytes/microglia
  • DHA
  • P2X7 receptor
  • Adult hippocampal neurogenesis
  • Endocannabinoid-mediated neuroprotection agaisnt synthetic neurotoxicants of the CNS.
  • Aerosol delivery of polymeric nanoparticles
  • Water-soluble synthetic polymers as exotic drug delivery carriers

Endocannabinoids as a novel therapeutic platform

The neuropsychological aspects of endocannabinoid based neuroprotection has emerged as a mature research area. My current research aim to investigate methods for exploiting the endocannabinoids platform for neurocognitive therapy.

Intracellular delivery of synaptamide to neurons by endocannabinoids

This notebook propose a experimental method for delivery of DHA to hippocampal stem/progenitor cells using endocannabinoid-mediated retrograde signaling.

Cannabimimetic effects of DHA on neurotransmission

P2X7 receptor mediate synaptogenic DHA signaling and intracellular signal transduction pathways relevant to PPAR-induced neural differentiation.

Programming of hippocampal progenitor cells by anandamide trafficking